Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Director, Program Management Jobs in North Carolina

Sort By: Relevance

$95K - $115K *

Champion product marketing by driving launches, pricing strategies, and sales enablement for key therapy lines. Collaborate cross-functionally to ensure compliance and optimize performance metrics, pa...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's shaping the future of linear technology by driving product strategy, optimizing market share, and enhancing customer solutions. Leverage your expertise to lead product development a...

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Drive go-to-market strategy for AI-powered healthcare solutions, collaborating cross-functionally to enhance product positioning, messaging, and performance. Own marketing execution and leverage insig...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$229K - $258K *

Lead the charge in shaping product security strategy, driving cross-functional initiatives, and embedding security by design into engineering workflows. Collaborate with teams to enhance vulnerability...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$175K - $400K *

Join a team that's shaping the future of digital supply chain management. You'll architect and optimize ERP, PLM, and inventory systems, ensuring data integrity and operational scalability across glob...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$165K - $180K *

Transform healthcare solutions by leading the design and development of scalable, high-performance systems. Collaborate with cross-functional teams and mentor junior engineers to drive innovation and...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in enhancing internal communications to connect a growing, remote workforce. Collaborate with leadership to create clear, engaging messages that align employees with company priorities...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $190K *

Empower our sales team by driving strategic growth in key accounts. Leverage your expertise in Enterprise SaaS to navigate complex sales in the Life Sciences sector, fostering partnerships and deliver...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$169K - $305K *

Shape the future of risk management by leading IT/IS governance initiatives, identifying strategic risks, and enhancing enterprise frameworks. Collaborate with senior leaders to ensure comprehensive o...

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$180K - $212K *

Drive growth through innovative demand generation strategies, leveraging data and analytics to enhance pipeline performance. Collaborate with cross-functional teams to optimize marketing efforts and l...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Media

$141K - $278K *

Engineer transformative HR solutions by leading ServiceNow HRSD implementations. Collaborate with cross-functional teams to design, develop, and deliver innovative HR services that enhance employee ex...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$121K - $164K *

Champion a team of analysts to enhance enterprise infrastructure services, ensuring reliable support and operational excellence. Collaborate with cross-functional teams to align priorities and drive c...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$198K - $298K *

Lead the charge in shaping the AMER Revenue Operations strategy, driving operational excellence and predictable outcomes. Collaborate with executive leadership to optimize sales processes and build a...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$236K - $354K *

Innovate and drive strategic initiatives as a Principal Technical Program Manager, aligning engineering, product, and business stakeholders to enhance organizational effectiveness and execution across...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$150K - $180K *

Advance your career by leading multi-million-dollar EPC projects, ensuring timely and budget-compliant execution while fostering a culture of safety and collaboration across a diverse global team...

Yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead FedRAMP compliance initiatives, coordinating cross-functional teams to ensure project success. Manage execution of strategies, schedules, budgets, and stakeholder engagements while driving accoun...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$141K - $278K *

Transform your career by leading ServiceNow HRSD solutions, collaborating with teams to design and implement innovative HR strategies, and managing project workstreams to enhance employee experiences...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$135K - $160K *

Transform observability in AI with strategic vision, driving technical progress across systems and agent telemetry, while enhancing developer experiences and guiding product direction at the intersect...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$137K - $231K *

Lead the charge in crafting impactful user experiences across multiple sectors. Drive design strategies, engage with customers, and collaborate closely with product and engineering teams to shape end...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $115K *

Optimize supply chain efficiency by leading end-to-end projects, collaborating with cross-functional teams, and implementing best practices to drive operational excellence and continuous improvement i...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Drive project success by collaborating with cross-functional teams to manage complex aerospace repair and overhaul projects. Ensure timely delivery, risk mitigation, and effective communication with s...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$160K - $200K *

Drive product innovation and strategy for a transformative portfolio, enhancing database management through AI integration and leading a high-performing team that shapes customer experience and busine...

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$229K - $267K *

Innovate the consumer digital experience by leading a cross-functional team to enhance our website, mobile app, and web portal. Define a multi-year vision, prioritize initiatives, and drive engagement...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Grow your career with a dynamic role leading R&D projects for innovative low-voltage power distribution solutions, managing cross-functional teams, and driving product development from concept to laun...

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Drive successful enterprise SaaS implementations by managing complex projects, coordinating resources, and ensuring stakeholder satisfaction while adhering to budget, timeline, and quality standards...

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.