Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Director, Program Management Jobs in North Carolina

Sort By: Relevance

$157K - $292K *

Elevate legal technology solutions by leading architecture design and integration with partners. Collaborate across teams to ensure scalable, secure offerings that meet customer needs while guiding a...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Media

$110K - $130K *

Optimize the Innovation portfolio by leading high-impact projects, collaborating with senior leaders, and driving strategic initiatives. Your role will ensure seamless operations and foster growth in...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $201K *

Inspire operational excellence as you lead a high-performing team in GMP manufacturing, driving continuous improvement and ensuring compliance with FDA standards while mentoring talent and solving com...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Empower a healthcare association by leading strategic initiatives, fostering partnerships, and driving revenue growth. Collaborate with stakeholders to enhance program excellence and ensure effective...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$110K - $130K *

Inspire and elevate design excellence as you lead a talented team, setting and maintaining visual standards, driving innovative campaigns, and partnering cross-functionally to advance Dandy's brand an...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Join a dynamic team to lead the development of innovative front-end and API applications, driving architectural design and technical strategy across complex projects while ensuring alignment with stra...

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$81K - $112K *

Lead the development of innovative solutions in wealth management, ensuring compliance and enhancing advisor/client experiences. Collaborate across teams to drive projects, analyze trends, and protect...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Execute project management strategies to drive successful construction outcomes. Collaborate with teams to ensure quality, safety, and client satisfaction across diverse sectors, while managing resour...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$180K - $210K *

Transform technology operations by leading strategic initiatives, enhancing cybersecurity, and fostering cross-functional collaboration to support mission-driven projects and a remote-first workforce...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Elevate project success by leading glass and panel initiatives, ensuring timely delivery and budget adherence while fostering strong client and team relationships across multiple projects in a dynamic...

Reposted yesterday

  •   Less than 5 years exp.  •   Real Estate & Construction

$80K - $95K *

Lead project execution in glass and panel management, ensuring timely delivery and budget adherence while fostering collaboration among teams and clients. Drive risk management and strategic planning...

Reposted yesterday

  •   Less than 5 years exp.  •   Real Estate & Construction

$150K - $180K *

Join a forward-thinking team to define and execute design strategy for AI-driven risk management tools, guiding designers and partners to deliver exceptional user experiences that prioritize risk unde...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$160K - $200K *

Unlock potential by leading enterprise change management for S/4HANA transformation. Collaborate with cross-functional teams to ensure business readiness, user proficiency, and sustained adoption acro...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$170K - $200K *

Empower success by leading strategic planning and scheduling for large-scale capital programs. Drive best practices, mentor teams, and influence executive stakeholders to ensure seamless project deliv...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$275K - $325K *

Drive the venture and private equity business by owning strategy, partnerships, and P&L. Collaborate with teams to establish Flex as the primary financial institution in the sector, leveraging your ex...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$225K - $265K *

Lead and mentor a diverse team of backend engineers in EDR remediation, transforming insights into actionable product capabilities while managing scope and fostering collaboration across engineering t...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Elevate product strategy and execution by leading cross-functional teams to drive innovation and market growth. Oversee the product lifecycle, mentor talent, and identify new business opportunities to...

2 weeks ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$139K - $235K *

Transform customer infrastructure management by owning the product vision and roadmap for a key control plane. Collaborate with engineering to enhance user experience and operational efficiency, drivi...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$186K - $233K *

Empower the future of real-world analytics by leading programming activities for observational studies, ensuring high-quality deliverables through collaboration with cross-functional teams and innovat...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$122K - $163K *

Lead the charge in clinical data management, ensuring high-quality data deliverables and effective study execution. Oversee risk management, vendor performance, and process improvements while collabor...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Optimize quality operations for large-scale data pipelines, ensuring high standards and consistency across diverse datasets. Lead a team to enhance efficiency and reliability in audio data processing...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $200K *

Drive the vision and strategy for next-gen platform products, focusing on TaxEx, Treasury, and BPaaS solutions. Collaborate with partners and stakeholders to create innovative offerings that expand be...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$190K - $240K *

Accelerate progress at strategic partnerships in the NAMER region by identifying, onboarding, and managing key partners. Drive revenue growth through collaboration, enablement, and relationship manage...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$122K - $173K *

Lead a dynamic team in managing cutting-edge hardware operations, ensuring optimal performance and safety in data center environments. Drive strategic initiatives while fostering collaboration and inn...

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$82K - $95K *

Lead the charge in planning and executing high-profile corporate events, managing teams and client relationships to deliver exceptional experiences for diverse audiences, while overseeing logistics, b...

2 days ago

  •   8 - 10 years exp.  •   Media

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.