Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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500

Director, Program Management Jobs in North Carolina

Sort By: Relevance

$100K - $120K *

Lead the charge in managing workplace design and construction projects, ensuring operational readiness and accountability across multiple sites while optimizing budgets and vendor performance for succ...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Champion digital transformation by leading delivery teams in Salesforce projects, ensuring excellence in project management, client relationships, and issue resolution while mentoring consultants and...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Champion a data-driven Customer Success program that enhances retention, proactively identifies risks, and efficiently engages a diverse customer base through innovative workflows and analytics. Lead...

RemoteRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Information Technology

$168K - $281K *

Lead the charge in Proactive Defense Operations, transforming threat data into automated defenses. Drive strategy, team performance, and operational excellence while collaborating across functions to...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Drive complex, multimillion-dollar IT programs with global impact, collaborating with C-suite leaders. Lead cross-functional teams to achieve strategic objectives, ensuring accountability and measurab...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Business Services

$120K - $145K *

Drive execution of complex technical initiatives, translating business vision into actionable programs. Collaborate with cross-functional teams to ensure alignment with company objectives and measurab...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$83K - $118K *

Unlock your potential by leading complex IT/SaaS projects, driving execution, and enhancing business processes. Collaborate with diverse teams to ensure project success while utilizing Agile methodolo...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$132K - $182K *

Drive program execution across high-priority workstreams in Customer Outcomes, managing threat intelligence partnerships and AI model initiatives. Collaborate with cross-functional teams to ensure tim...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Lead the charge in delivering Murex project implementations, managing stakeholder relationships, and ensuring governance across multiple regions while driving financial metrics and performance indicat...

2 days ago

  •   11 - 15 years exp.  •   Technical Services

$130K - $241K *

Shape the future of digital products by leading cross-functional teams to innovate and launch AI-driven solutions that enhance customer experiences and drive measurable business impact...

Yesterday

  •   5 - 7 years exp.  •   Business Services

$155K - $180K *

Drive successful delivery of complex, multi-year programs in a dynamic environment. Collaborate with cross-functional teams to manage scope, budget, and timelines while ensuring client satisfaction an...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Champion operational excellence across a large district, driving revenue growth and client satisfaction while leading diverse teams to achieve financial targets and maintain high standards of service...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$125K - $135K *

Lead the charge in developing and managing enterprise proposals and plans, ensuring compliance and quality across submissions. Collaborate with cross-functional teams to enhance win strategies and dri...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$173K - $255K *

Empower global expansion by leading customer operations strategy, managing complex programs, and driving continuous improvement across international markets. Collaborate with cross-functional teams to...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$95K - $115K *

Transform operational efficiency by leading strategic projects in reverse logistics and refurbishment. Collaborate with cross-functional teams to enhance processes, optimize workflows, and drive conti...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $125K *

Champion the development of healthcare marketing tools by guiding cross-functional teams through the product lifecycle, driving innovative features and optimizing user experiences to enhance HCP engag...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead the migration of critical shopfloor applications, ensuring timely delivery, managing risks, and fostering collaboration across technical teams and stakeholders to drive digital transformation in...

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Drive client satisfaction as a Senior Project Manager, overseeing eDiscovery projects, managing budgets, and consulting on best practices. Lead teams, enhance workflows, and ensure timely delivery whi...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$123K - $207K *

Champion the design and ownership of a robust People Data Access & Governance framework, ensuring responsible data access while partnering with cross-functional teams to navigate compliance and ethica...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$160K - $190K *

Architect enterprise-grade AI solutions, guiding design and integration of generative AI and ML across complex platforms. Leverage deep expertise to create scalable architectures that optimize perform...

1 week ago

  •   15+ years exp.  •   Information Technology

$161K - $210K *

Elevate workforce management by leading recruitment, onboarding, and performance strategies. Drive clinician readiness and productivity while ensuring quality care through data-driven decision-making...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$185K - $344K *

Join a dynamic team driving strategic planning and performance management across analytics capabilities. Lead portfolio governance and execution initiatives to align resources and priorities, ensuring...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Drive success as a Program Manager, leading a multidisciplinary team in delivering enterprise IT solutions, ensuring quality oversight, technical direction, and effective customer coordination across...

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$104K - $130K *

Join a team that's driving project success in mission-critical environments. As a Project Manager, you'll oversee design and construction phases, manage stakeholder relations, and ensure project profi...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$130K - $155K *

Transform technical architecture by leading and developing a team of Solution Architects. Ensure effective resource allocation, remove roadblocks, and foster collaboration while navigating evolving so...

5 days ago

  •   5 - 7 years exp.  •   Staffing

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.