Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
$108K - $130K *
Accelerate project execution by leading medium-sized initiatives, ensuring compliance with standards, and guiding cross-functional teams to deliver optimal results while prioritizing strategic alignme...
Reposted 1 week ago
Principal Engineer-Configuration Management Governance
$131K - $219K *
Grow your career with us as a Principal Engineer, leading Configuration Management processes and driving innovation across Gas Power products. Collaborate with cross-functional teams to enhance produc...
2 weeks ago
Director, CMC Product Development - Small Molecule
$199K - $258K *
Drive your career forward by leading the CMC development of small molecule drug products. Collaborate cross-functionally to ensure successful formulation, process development, and regulatory submissio...
3 weeks ago
Director, AI Solutions Strategy & Planning
$206K - $261K *
Accelerate the commercialization of AI-driven solutions by leading strategy and planning efforts. Collaborate cross-functionally to define go-to-market frameworks, enhance retailer experiences, and dr...
2 weeks ago
Director, Strategic Operations
$200K - $240K *
Engage in strategic initiatives that drive growth and operational excellence. Collaborate with senior leadership to shape enterprise strategy and lead cross-functional programs, ensuring impactful out...
Reposted 1 week ago
Moveworks Consulting Senior Manager
$171K - $338K *
Join a team that's transforming HR and IT service delivery through AI. As a Senior Manager, you'll lead engagements, shape strategies, and advise clients on innovative solutions, driving growth and en...
2 weeks ago
Moveworks Consulting Senior Manager
$171K - $338K *
Lead the charge in transforming HR and IT service delivery through AI. As a Senior Manager, you'll oversee multiple engagements, build client relationships, and drive practice growth while mentoring t...
2 weeks ago
$110K - $130K *
Innovate product management by leading the evolution of legacy and cloud solutions. Drive customer adoption, improve outcomes, and enhance user experience while collaborating with cross-functional tea...
4 weeks ago
$95K - $158K *
Champion safety excellence by leading enterprise-wide initiatives, enhancing training, and ensuring compliance. Collaborate across departments to drive impactful safety programs and data-driven soluti...
1 week ago
Technical Program Manager, Money-as-a-Service
$135K - $160K *
Champion the delivery of large-scale technical programs by leading cross-functional teams, enhancing communication and operational efficiency, and driving strategic decisions to empower users and tack...
Reposted 3 weeks ago
Deputy Program Manager/Project Manager
$110K - $130K *
Join a team that's dedicated to delivering high-quality construction projects. Oversee project management, lead teams, and strengthen client relationships while ensuring projects are completed on time...
6 days ago
Senior Manager, Solution Engineering - DocV
$135K - $160K *
Drive customer success and system reliability by leading a high-impact, agile engineering team focused on short-term initiatives that enhance product adoption and solve complex integration challenges...
Reposted 3 weeks ago
Vice President of Product Management
$235K - $265K *
Champion product innovation by leading a dynamic team to define strategy, drive decisions, and ensure successful launches that align with company growth and customer needs in the health technology sec...
2 weeks ago
Program Manager II - Product Development
$113K - $165K *
Empower cross-functional teams by leading complex product development projects, ensuring alignment with business goals while driving continuous improvement and optimizing productivity throughout the p...
Today
Senior Manager, International Reporting
$170K - $200K *
Shape the future of international financial reporting by leading statutory and sustainability reporting for global entities, ensuring compliance and accuracy while collaborating with cross-functional...
Today
$110K - $130K *
Lead the charge in managing complex public safety projects, ensuring timely delivery and high customer satisfaction. Oversee a diverse portfolio while collaborating with cross-functional teams to driv...
1 week ago
Sr. Project Manager, CSP - Remote
$160K - $246K *
Lead the charge in delivering innovative CSP offerings by managing cross-functional teams, ensuring project execution within budget and timelines, and driving solutions in a dynamic environment. Stron...
1 week ago
Sr. Project Manager, CSP - Remote
$160K - $246K *
Lead cross-functional teams to deliver innovative CSP offerings, focusing on compute, storage, and GPU products. Utilize senior project management skills to ensure timely and budget-compliant executio...
1 week ago
Director, Engineering (AI Patient Engagement Platform)
$180K - $230K *
Join a dynamic team as you lead engineering efforts to develop an AI Patient Engagement Agent, transforming clinical trials by automating patient interactions and enhancing operational efficiency for...
2 weeks ago
$135K - $160K *
Transform our growth marketing strategy by driving demand generation and managing a high-performing team. Collaborate with cross-functional leaders to optimize pipeline performance and leverage automa...
1 week ago
Sr Program Manager, Cybersecurity
$120K - $145K *
Shape the future of cybersecurity by leading strategic initiatives and managing complex programs across IT, OT, and IoT. Drive collaboration with diverse stakeholders to enhance security postures and...
Reposted 5 days ago
$124K - $156K *
Shape the future of AI Services by owning product strategy and execution. Collaborate with engineering teams to define agentic capabilities, drive tool strategies, and establish AI quality standards t...
2 weeks ago
Director of E-Commerce & Digital Product
$130K - $160K *
Elevate digital experiences by guiding site operations and enhancing user engagement. Collaborate with cross-functional teams to implement innovative features and optimize performance metrics, driving...
Reposted 1 week ago
Manager, Strategy & Operations
$120K - $180K *
Drive operational excellence by managing the leadership team's cadence, metrics, and contract operations. This hands-on role blends business judgment with execution, ensuring alignment and efficiency...
2 weeks ago
$135K - $160K *
Champion a team of product managers to drive innovative software solutions. Shape product direction, enhance customer understanding, and elevate product quality while fostering leadership and collabor...
1 week ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.