Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
$100K - $135K *
Unlock potential by leading project controls for complex projects. Oversee planning, cost management, and risk assessment while mentoring a team to ensure timely, budget-compliant project delivery in...
1 week ago
Program Director, Professional Services
$180K - $200K *
Accelerate progress at regional Professional Services by leading teams, driving growth and quality in consulting engagements while fostering strategic partnerships and developing innovative service of...
Reposted 2 weeks ago
$110K - $130K *
Elevate global post-market surveillance by leading a team focused on safety, compliance, and performance of medical devices. Drive field actions, analyze data, and collaborate cross-functionally to en...
1 week ago
Director, Business and Data Analytics
$164K - $314K *
Unlock your potential by leading strategic data initiatives that drive business success. Collaborate with cross-functional teams to enhance analytics capabilities and deliver actionable insights, shap...
1 week ago
Director, Quantitative Systems Pharmacology
$188K - $313K *
Lead the charge in advancing quantitative systems pharmacology through innovative modeling and simulation strategies, driving integration across drug discovery and development to enhance patient outco...
1 week ago
$171K - $245K *
Champion the strategic product lifecycle for healthcare solutions, driving innovation and collaboration across teams to enhance patient access and streamline workflows. Deliver measurable outcomes tha...
Yesterday
Procurement Manager, Process & Policy
$93K - $159K *
Advance your career by developing and standardizing Procurement processes that enhance compliance and efficiency. Collaborate with cross-functional teams to create clear documentation and governance p...
6 days ago
Implementation Manager - Data Solutions
$91K - $145K *
Shape the future of data solutions by leading complex pharmacy claims and physician-level data integrations. Collaborate with cross-functional teams to deliver high-quality, scalable solutions that me...
3 weeks ago
Senior Manager, Global Meeting Planning
$145K - $168K *
Drive impactful medical congress operations by leading planning, execution, and cross-functional collaboration. Own vendor relationships and budgets while ensuring compliance and delivering high-quali...
2 weeks ago
Senior Technical Product Manager
$153K - $213K *
Champion the development of a key platform, driving strategy, success metrics, and technical depth while collaborating across teams to deliver impactful solutions that meet customer needs and enhance...
3 weeks ago
Project Controls Managers & Directors - Project Farma
$99K - $199K *
Join a dynamic team to lead project controls in life sciences, enhancing project delivery through data-driven insights and collaboration. Drive excellence in cost, schedule, and performance management...
2 days ago
Project Controls Managers & Directors - Project Farma
$99K - $199K *
Join a team that's dedicated to enhancing patient lives by leading project controls for biomanufacturing. Collaborate with cross-functional teams to deliver high-quality life sciences projects while m...
2 days ago
Director Software Engineering - Central Security
$180K - $220K *
Drive the development of innovative security systems using AI/ML, managing risk across identity and access management. Collaborate with cross-functional teams to enhance security while maintaining ope...
1 week ago
$110K - $130K *
Join a dynamic team to lead proposal and security response efforts, driving innovation and quality. Manage a skilled group, streamline processes, and enhance collaboration across functions to achieve...
2 weeks ago
Principal Product Manager, Design Systems & Accessibility
$173K - $290K *
Lead product strategy for design systems and accessibility, driving innovation and adoption across teams. Shape integrated roadmaps, enhance product health, and ensure alignment with evolving AI-nativ...
2 weeks ago
$110K - $130K *
Champion strategic sourcing initiatives across diverse categories, leading a high-performing team to drive measurable value. Foster partnerships, negotiate with suppliers, and implement innovative sol...
Reposted 2 days ago
Director of Product Management, Early Childhood & Public Sector Solutions
$110K - $140K *
Drive product innovation by leading the development of AI-enabled solutions for public sector agencies, enhancing early childhood systems through strategic vision, technical architecture, and customer...
5 days ago
$110K - $130K *
Drive your career forward as a Senior Project Manager overseeing multi-million dollar projects. Collaborate with cross-functional teams to ensure project success, maintain quality standards, and foste...
Reposted 2 days ago
Senior Product Manager, Data Products
$130K - $155K *
Elevate data product experiences by defining metrics that drive value for Mural. Collaborate across teams to shape insights, enhance reporting, and ensure data integrity, empowering organizations to m...
1 week ago
$183K - $215K *
Shape the future of North American inland transportation by leading product strategy and development. Collaborate with cross-functional teams to deliver actionable insights and drive market success in...
5 days ago
Managing Director, Data, AI, & Cloud
$180K - $220K *
Shape the future of data-driven solutions by leading our Data, AI & Cloud practice. Drive strategic growth, manage P&L, and inspire cross-functional teams to deliver innovative consulting solutions gl...
1 month ago
Senior Director, Head of R&D Governance and Portfolio Management
$228K - $342K *
Advance the future of R&D governance and portfolio management by leading strategic decision-making processes, optimizing operational efficiency, and ensuring seamless progression of therapeutic assets...
Today
Senior Director, Product Finance
$227K - $280K *
Lead strategic finance initiatives to empower product decisions, driving financial evaluations and business cases for new product lines. Collaborate with C-suite and product teams to optimize resource...
2 weeks ago
Project Controls Manager (Cost)
$130K - $165K *
Lead the charge in managing cost controls for complex construction projects, ensuring accurate financial insights and risk identification. Collaborate with diverse teams to support informed decision-m...
2 weeks ago
Senior Director Government Programs
$154K - $196K *
Unlock potential by leading strategic government programs, managing P&L, and driving operational excellence. Oversee contract delivery, mentor staff, and foster client relationships to ensure growth a...
3 weeks ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.