Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Director, Program Management Jobs in North Carolina

Sort By: Relevance

$110K - $130K *

Champion enterprise ERP transformations by leading complex implementations and upgrades. Collaborate with cross-functional teams to drive digital initiatives, ensuring projects meet scope, budget, and...

5 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Join a team that's redefining cyber risk management by leading independent oversight across critical domains. Drive strategic initiatives, influence stakeholders, and enhance cybersecurity posture whi...

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$210K - $273K *

Shape the future of security by defining product vision and strategy for AI-powered capabilities, enhancing risk visibility, and driving adoption across engineering teams to ensure secure development...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Elevate your career by partnering with the CEO to drive strategic initiatives, optimize operations, and enhance organizational effectiveness. You'll tackle complex challenges, support executive decisi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$160K - $200K *

Optimize operational excellence and client service as a senior leader overseeing a complex Connected Solutions hub, ensuring high standards in production, technical operations, and team performance fo...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Media

$170K - $230K *

Elevate the sales strategy and operations by partnering with leadership to enhance productivity, implement AI solutions, and drive data-driven decision-making. Lead a team to optimize processes and en...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$101K - $152K *

Champion innovative solutions by leveraging Epic expertise to enhance operational efficiency and drive strategic initiatives across healthcare environments, ensuring high-performance standards and cli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Lead strategic product initiatives in advanced surgical technologies, driving development and commercialization efforts. Collaborate with cross-functional teams to enhance orthopedic outcomes and proc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $190K *

Advance product strategy and innovation by leading cross-functional teams to drive the vision, roadmap, and delivery of shared commercial platforms, ensuring alignment with business priorities and tec...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$128K - $178K *

Lead the evolution of our CMS and AI web strategy, driving product vision and execution for public sector clients. Collaborate with cross-functional teams to deliver innovative, customer-focused solut...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$180K - $215K *

Lead the charge in transforming supply chain technology strategies, driving innovation and operational excellence across S2P and O2C value streams. Collaborate with cross-functional teams to enhance d...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$74K - $128K *

Lead project execution initiatives, ensuring timely delivery while maintaining safety, quality, and customer satisfaction. Collaborate across teams to optimize resource management and stakeholder enga...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$160K - $238K *

Build and scale the Partner Operations function, turning complexity into leverage by designing systems and processes that enhance partnerships and align with revenue goals for measurable impact and st...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$136K - $160K *

Advance the software delivery process by managing launches and releases, ensuring accuracy and efficiency through automation and collaboration with cross-functional teams. Design workflows and tools t...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$79K - $94K *

Optimize training and workflow processes by leading program development, mentoring trainers, and collaborating with stakeholders to enhance provider experiences and operational efficiency across Care...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$180K - $200K *

Elevate healthcare technology by owning mobile and web apps that enhance clinician workflows. Drive product direction, prioritize initiatives, and ensure patient safety while leveraging AI to improve...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $275K *

Elevate data strategy and reporting for the System Performance Organization, transforming complex robotics data into compelling narratives for executive stakeholders while fostering team growth and al...

RemoteRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Transportation

$130K - $140K *

Unlock your potential as a leader in program performance management, guiding teams in cost and schedule development for high-value engineering programs. Collaborate across functions to drive success i...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$125K - $150K *

Lead and develop engineering teams focused on clinical data integration and insights. Drive the direction of data pipelines and ensure impactful, equitable health outcomes through effective collaborat...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Lead core banking system conversions for credit unions, ensuring seamless project delivery through effective stakeholder communication, data migration, and interface integration, while managing risks...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $145K *

Shape the future of product innovation by leading strategic portfolio management initiatives that align with business goals, drive profitability, and enhance market competitiveness through effective l...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Drive your career with a leadership role overseeing brand advertising strategy, budget, and execution across multiple channels. Lead a team and collaborate with agencies to enhance brand visibility an...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$110K - $115K *

Join a team that's redefining healthcare project management. Lead integrated initiatives, mentor talent, and drive excellence across diverse campaigns while fostering collaboration and innovation in a...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform product operations by enhancing collaboration across teams and streamlining the launch processes. Utilize data-driven insights and AI to identify bottlenecks and drive efficiency, ensuring s...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Legal & Accounting

$200K - $300K *

Lead technical and strategic efforts to modernize power grids across North America, enhancing customer solutions through innovative hardware and software. Engage with stakeholders to drive transformat...

Reposted 1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.