Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Director, Program Management Jobs in North Carolina

Sort By: Relevance

$115K - $135K *

Join a team that's transforming Medicaid agencies through expert OCM strategies. Leverage your project management and change management skills to enhance health outcomes and build stronger communities...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$170K - $250K *

Unlock potential by owning a product area end-to-end, collaborating with engineering and customers to drive innovation and deliver impactful solutions in a dynamic market...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Staffing

$90K - $110K *

Unlock potential by managing pharmaceutical programs, ensuring smooth operations, client relationships, and strategic execution while overseeing performance metrics and enhancing team collaboration...

North Carolina, USRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$134K - $207K *

Drive cross-functional program management initiatives, ensuring successful execution from capture to delivery. Collaborate with stakeholders to align objectives, manage risks, and leverage GM's capabi...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$182K - $215K *

Transform executive engagement by building strategic advisor relationships, designing impactful experiences, and leveraging industry insights to elevate pay governance as a strategic priority for clie...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Unlock your potential by independently managing local or regional clinical trials, ensuring adherence to budget, quality, and performance. Collaborate across teams to drive project success, enhance ef...

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's driving innovation in R&D by leading product development and mentoring engineers. This role emphasizes organizational growth, technical excellence, and collaboration to elevate engi...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$201K - $251K *

Lead strategic forecasting initiatives to drive decision-making in oncology. Collaborate with cross-functional teams to develop long-term models and communicate insights that shape product and portfol...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$93K - $166K *

Transform the future by leading complex projects that drive innovation and efficiency. Collaborate with cross-functional teams to deliver business value while managing scope, schedule, and resources i...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Collaborate with cross-functional teams to enhance Salesforce solutions, driving process improvements and operational excellence. Contribute hands-on to configuration, data management, and user adopti...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$70K - $105K *

Collaborate with cross-functional teams to drive project execution and operational excellence in medical communications. Leverage your project management skills to ensure timely delivery and high-qual...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the charge in managing complex manufacturing projects, ensuring client satisfaction and project delivery from concept to execution. Collaborate with design teams to translate production intent in...

Reposted yesterday

  •   8 - 10 years exp.  •   Real Estate & Construction

$150K - $180K *

Transform strategic initiatives into actionable plans by coordinating across Business Management, GTM, and Operations. Drive measurable outcomes through effective governance and execution, ensuring al...

3 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$119K - $199K *

Transform the KeysightAccess Program by collaborating with global sales teams to enhance commercial strategies, streamline transactions, and drive program adoption, ensuring effective execution and su...

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Champion specialized military medical training services, overseeing program coordination, instructor supervision, and quality control to ensure effective training execution for Marine Forces Special O...

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$114K - $190K *

Join a team that's driving the successful execution of complex Power Conversion projects, overseeing all phases from planning to closure. Ensure financial performance, quality, and customer satisfacti...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$120K - $145K *

Engage with cross-functional teams to drive AI security product marketing initiatives, focusing on buyer insights, competitive analysis, and effective sales enablement. Collaborate on launches and con...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$188K - $230K *

Transform strategic visions into reality by owning product lifecycle from ideation to impact. Collaborate across teams to deliver innovative solutions, drive customer satisfaction, and ensure business...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Join a team that's dedicated to delivering innovative architectural solutions. As a Project Manager, you'll lead complex projects, collaborate with clients and team members, and drive design excellenc...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $120K *

Drive impactful business application initiatives by leading cross-functional projects that enhance efficiency and performance. Collaborate with stakeholders to ensure successful delivery of Microsoft...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $120K *

Elevate talent management by executing core programs, enhancing employee experience, and driving performance initiatives. Lead cross-functional projects, ensuring accountability and operational contin...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $120K *

Unlock the potential of Talent Management by leading performance cycles, enhancing employee relations, and driving strategic initiatives. This hands-on role requires expertise in HR operations, projec...

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$125K - $169K *

Lead the charge in enhancing customer success initiatives by driving engagement, optimizing processes, and fostering strong relationships. Collaborate with cross-functional teams to ensure exceptional...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Lead the charge in developing our ELERA channel strategy. Collaborate with partners to drive revenue, build enablement programs, and expand our market reach while ensuring success through effective ex...

1 month ago

  •   11 - 15 years exp.  •   Information Technology

$76K - $115K *

Join a team that's shaping the future of customer education through innovative instructional design. Leverage your expertise to create engaging learning experiences that empower users and drive succes...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.