Explore $100K+ Jobs in Michigan

Discover professional opportunities across Michigan with Ladders, where job seekers can explore vetted roles offering salaries of $100,000 or more. From established employers in Detroit to growing companies in Grand Rapids, Ann Arbor, Lansing, and other communities, Michigan offers career paths across a diverse range of industries and leadership levels.

Find Opportunities Across Michigan

Search jobs throughout the state, including major employment hubs such as Detroit, Grand Rapids, Ann Arbor, Lansing, and Kalamazoo. Depending on the role and employer, opportunities may offer on-site, hybrid, or remote work arrangements. Review each listing for location, compensation, responsibilities, and workplace expectations.

Explore Michigan Industries

Michigan is known for its automotive and advanced manufacturing industries, while also supporting opportunities in technology, healthcare, finance, engineering, supply chain, energy, and professional services. Employers seek experienced professionals for specialized individual-contributor roles as well as management and executive positions.

Build Your Next Career Move

Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Compare opportunities, identify roles that fit your experience, and tailor your résumé to highlight measurable results, leadership, and relevant expertise. Job availability and compensation vary by employer, location, and qualifications.

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$138K - $180K *

Shape the future of medical device development by driving project execution, collaboration, and innovation within a dynamic Research & Development team focused on enhancing healthcare outcomes and pat...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Join a team that's redefining scientific data management in drug discovery. Lead the scientific data team, bridging scientists and engineers to ensure data integrity, quality, and innovative solutions...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape the future of product development by leading cross-functional teams to deliver innovative solutions from concept to launch, ensuring alignment with business goals and quality standards...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$184K - $253K *

Drive global pharmacovigilance efforts by managing safety data, leading clinical development strategies, and collaborating across teams to enhance product safety and efficacy throughout their lifecycl...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $201K *

Lead the charge in shaping and evolving a global web ecosystem, overseeing strategy, operations, and governance to deliver high-performing digital experiences that drive engagement and business growth...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$170K - $220K *

Drive product strategy and development to enhance clinician experience, optimizing patient care through innovative solutions and stakeholder collaboration across a nationwide healthcare network...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$149K - $205K *

Elevate innovation at the forefront of foodtech, agritech, and infrastructure. Lead strategic initiatives, build ecosystems, and drive new ventures to shape the future landscape of Mitsubishi Electric...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$100K - $150K *

Lead the charge in managing complex, technically sophisticated projects, focusing on data centers. Collaborate with diverse stakeholders to ensure project alignment with client goals, budgets, and sch...

RemoteRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$120K - $193K *

Transform enterprise security by leading product strategy and delivery, focusing on data protection and compliance. Drive innovation through AI integration, ensuring scalable solutions that meet evolv...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Drive innovative product development from concept to launch, managing schedules, budgets, and resources. Engage cross-functionally to ensure alignment and execution across diverse projects in a dynami...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$119K - $222K *

Unlock your potential as you drive innovation in legal research, collaborating with cross-functional teams to develop AI-enabled solutions that enhance user experiences and ensure compliance with indu...

1 week ago

  •   5 - 7 years exp.  •   Media

$119K - $222K *

Join a team that's shaping the future of product management by driving strategic vision and execution for complex, AI-enabled products. Collaborate cross-functionally to enhance customer experiences a...

2 weeks ago

  •   5 - 7 years exp.  •   Media

$113K - $197K *

Lead the charge in defining product strategy and roadmap, translating business objectives into actionable plans. Collaborate with cross-functional teams to ensure successful implementation and operati...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$65K - $116K *

Drive exceptional client experiences by leading delivery operations, managing relationships, and leveraging analytics to identify service gaps. Collaborate cross-functionally to ensure seamless execut...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $124K *

Drive impactful SAP projects as a Project Manager/Scrum Master, leading teams to deliver innovative solutions. Collaborate with stakeholders, manage product backlogs, and ensure agile practices to mee...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $210K *

Lead the charge in solving complex carrier connectivity challenges in commercial insurance. Collaborate with cross-functional teams to streamline workflows and enhance product delivery, ensuring seaml...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $150K *

Join a dynamic team to optimize supply chain operations, ensuring efficient medication delivery from pharmacy partners to patients. Oversee systems, processes, and a team to scale operations amidst ra...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$221K - $270K *

Lead the global Application Engineering team for Electrical Architecture & Electronics, driving technical engagement with OEMs and Tier suppliers, translating market insights into scalable solutions...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Business Services

$88K - $105K *

Lead the charge in strategic submarine pursuits by managing proposal activities, fostering customer relationships, and driving business development initiatives across functional teams to achieve organ...

3 weeks ago

  •   8 - 10 years exp.  •   Food & Beverages

$80K - $95K *

Drive project execution by leading cross-functional teams, ensuring customer satisfaction, and achieving targets for timing, cost, and quality in engineering support throughout product development and...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$134K - $219K *

Lead clinical laboratory operations for precision medicine projects, ensuring timely deliverables and risk management across therapeutic areas. Collaborate with cross-functional teams to support clini...

RemoteRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$123K - $218K *

Take ownership of complex project delivery across multiple teams, ensuring timely execution of high-stakes initiatives. Collaborate with engineers and researchers to optimize project management practi...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Innovate and lead the MyGeotab workflows, ensuring usability and reliability while driving evolution and collaboration across product domains to enhance customer experience and operational efficiency...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Transportation

$80K - $95K *

Contribute to high-quality module delivery by managing quality systems, driving continuous improvement, and ensuring customer satisfaction through effective leadership and data-driven decision-making...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Reimagine client partnerships by managing complex relationships, driving performance, and leading recovery strategies. Collaborate with executives to ensure client success and identify growth opportun...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs can I find in Michigan?question toggle

    Listings may include senior and executive roles in fields such as engineering, technology, healthcare, finance, manufacturing, supply chain, and professional services. Available positions vary over time.

  • Which Michigan cities have professional job opportunities?question toggle

    Opportunities can be found in Detroit, Grand Rapids, Ann Arbor, Lansing, Kalamazoo, and other Michigan communities. Search by location to find roles that match your preferences.

  • Are Michigan jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional job opportunities with salaries of $100,000 or more. Check individual listings for details about the employer, role, location, and compensation.

  • Do Michigan jobs offer remote or hybrid work?question toggle

    Some employers may offer remote or hybrid arrangements, while others require on-site work. Review each job listing for its specific work-location expectations.