Director of Operational Excellence Jobs

Discover Director of Operational Excellence opportunities on Ladders, where professionals can explore vetted jobs paying $100,000 or more. These senior leaders help organizations improve performance, streamline processes, and build a culture of continuous improvement. Roles span industries and may focus on enterprise transformation, quality, supply chain, manufacturing, healthcare, technology, or business operations.

What Does a Director of Operational Excellence Do?

A Director of Operational Excellence develops and leads initiatives that make an organization more effective, resilient, and customer-focused. Responsibilities often include identifying process gaps, setting improvement priorities, establishing performance measures, and partnering with executives and operational teams to deliver sustainable results. Depending on the employer, the role may oversee Lean, Six Sigma, change management, process design, or operational transformation programs.

Skills and Qualifications Employers Seek

Employers commonly look for strategic leadership, analytical problem-solving, change management, and the ability to influence across departments. Experience with continuous improvement methods such as Lean or Six Sigma, along with data analysis, project portfolio management, and KPI development, can be valuable. Many positions require a bachelor’s degree and substantial relevant experience; some prefer an advanced degree or professional certification.

Industries and Career Opportunities

Director of Operational Excellence roles are available in sectors where reliable, efficient processes are critical, including manufacturing, healthcare, financial services, logistics, retail, and technology. The scope varies: some directors lead improvement teams at a single site, while others shape operating models and transformation efforts across multiple business units or global organizations. Career paths may lead to vice president of operations, chief operating officer, or enterprise transformation leadership.

Find Director of Operational Excellence Jobs on Ladders

Use Ladders to explore vetted senior-level opportunities with salaries of $100,000 or more. Compare roles by industry, location, and scope, and look for positions that match your experience in operational strategy, process improvement, and executive leadership.

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$176K - $205K *

Lead the charge in executing complex capital projects and liquid processing strategies. Drive innovation and efficiency across manufacturing networks while mentoring engineering teams and ensuring pro...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Food & Beverages

$500K+*

Lead the transformation of media ingestion and distribution systems, driving automated, AI-powered workflows that enhance efficiency and accelerate content delivery to a global audience. Collaborate a...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$200K - $235K *

Transform global enterprise customer relationships by driving EHS/ESG success through consultative account management, strategic growth initiatives, and collaboration with cross-functional teams to de...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$190K - $275K *

Lead the strategy and execution of AI and workflow capabilities, driving innovative solutions that enhance user experience and business outcomes across a scalable product suite. Mentor a team of Produ...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$132K - $232K *

Redefine career mobility strategies by integrating talent marketplace capabilities, enabling associates to explore growth opportunities through data-informed solutions and collaborative practices acro...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Business Services

$120K - $145K *

Join a team that's shaping the future of CRM solutions, driving technical leadership and product strategy within the Salesforce ecosystem. Collaborate with cross-functional teams to enhance client por...

Philadelphia, PARemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Transform business growth by generating leads and fostering client relationships across Chemicals, O&G, Power, Metals, and Advanced Facilities sectors, driving profitability and strategic sales initia...

Baton Rouge, LARemote

2 days ago

  •   8 - 10 years exp.  •   Technical Services

$107K - $145K *

Drive growth by identifying and securing new business opportunities in risk management and medical education. Collaborate with teams to develop proposals, manage sales pipelines, and ensure alignment...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $140K *

Elevate client success by leading MSP program implementations from discovery to launch. Collaborate with cross-functional teams to ensure alignment with client objectives, manage risks, and drive proj...

Pennsylvania, USRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$157K - $207K *

Shape the future of biology by leading creative initiatives that elevate our brand. Collaborate closely with leadership to craft compelling narratives and visuals, while managing a growing team and bu...

Emeryville, CARemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$114K - $151K *

Unlock potential by leading the HV overhead switchgear portfolio, driving product strategy, market development, and cross-functional collaboration to achieve profitable growth and enhance utility solu...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$170K - $200K *

Lead cross-functional integration of data, analytics, evaluation, and governance to enhance healthcare AI products. Drive roadmap ownership, optimize workflows, ensure data quality, and foster collabo...

Palo Alto, CARemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$88K - $134K *

Shape the future of customer success by leading the deployment of IoT solutions for enterprise clients. Your role will bridge sales and strategy, ensuring clients maximize the value of their technolog...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$270K - $365K *

Lead a dynamic engineering organization to transform offensive capabilities into proactive defense. Shape strategy, scale teams, and deliver innovative solutions across multiple pillars, ensuring robu...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$256K - $288K *

Lead the charge in clinical trial oversight and data interpretation, ensuring safety and efficacy of pipeline products through expert collaboration and strategic planning, aligning clinical activities...

Waltham, MARemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$156K - $234K *

Transform global MSP marketing by leading strategy, driving partner engagement, and executing campaigns. Collaborate with regional teams to enhance pipeline and revenue while ensuring effective partne...

Connecticut, USRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Elevate engineering success by partnering with leadership to drive strategic execution, fostering alignment across teams, and leveraging data-driven insights for impactful decision-making in a dynamic...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $185K *

Lead client engagements in Real-World Data solutions, ensuring operational excellence and strong outcomes. Collaborate cross-functionally to translate client objectives into actionable plans, driving...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Drive mobile engineering excellence across diverse product teams, ensuring strategic direction, fostering collaboration, and enhancing delivery. Lead managers, shape architecture, and cultivate a prod...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$90K - $120K *

Champion operational excellence by transforming data into actionable insights, leading cross-functional projects, and driving process improvements to enhance performance and scalability in a dynamic e...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$135K - $150K *

Join a team that's shaping the future of healthcare by leading M&A integration efforts. Drive strategic initiatives, manage high-stakes projects, and collaborate with senior leadership to enhance grow...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$80K - $120K *

Transform our proposal development process by crafting compelling narratives and presentations. Collaborate with cross-functional teams to enhance storytelling and optimize resources, ensuring our cap...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $135K *

Support the growth of health plan accounts by fostering client relationships, analyzing data, and driving retention in a fast-paced, independent role. Leverage strong communication and analytical skil...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$104K - $141K *

Lead cross-functional initiatives to optimize operational efficiency, budget planning, and resource allocation, fostering collaboration across business units to drive organizational goals and financia...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $140K *

Drive innovative media strategies for healthcare clients, leveraging audience insights and performance data. Collaborate with cross-functional teams to enhance planning processes and deliver impactful...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Operational Excellence do?question toggle

    A Director of Operational Excellence leads initiatives to improve organizational performance, processes, quality, and efficiency. The role often includes setting improvement strategy, tracking KPIs, guiding transformation projects, and helping teams adopt sustainable ways of working.

  • What qualifications are commonly required for Director of Operational Excellence jobs?question toggle

    Employers often seek a bachelor’s degree, extensive experience in operations or continuous improvement, and a record of leading cross-functional change. Lean or Six Sigma expertise, data analysis skills, and an advanced degree or relevant certification may be preferred.

  • How much do Director of Operational Excellence jobs pay?question toggle

    Compensation varies by industry, location, company size, and role scope. Ladders focuses on vetted professional jobs paying $100,000 or more, including senior operational excellence opportunities.

  • Which industries hire Directors of Operational Excellence?question toggle

    Manufacturing, healthcare, logistics, financial services, retail, technology, and other industries hire these leaders to improve processes, manage transformation, and strengthen operational performance.

  • What career paths can follow this role?question toggle

    Experienced Directors of Operational Excellence may advance to vice president of operations, chief operating officer, enterprise transformation executive, or other senior leadership positions.