Are you looking for high-paying Director of Information Systems jobs? You've come to the right place. We host a wide range of jobs in this category that pay $100K or more.
Directors of Information Systems oversee an organization's IT strategy and ensure that systems, infrastructures, and networks operate smoothly.
Typical qualifications include a bachelor's or master's degree in IT or related fields and several years of experience.
Executive Director, Payment Transformation (Work from home)
$161K - $299K *
Advance transformative payment strategies and VBC model design while overseeing robust analytics and administration operations impacting over $2B in provider payments annually. Champion cross-departme...
Yesterday
$150K - $200K *
Lead the charge in building a world-class corporate communications function that amplifies narratives and enhances brand presence through storytelling, media relations, and strategic engagement initia...
Reposted 4 weeks ago
Virtual Client Information Officer (vCIO)
$90K - $120K *
Unlock potential by serving as a strategic advisor for clients, aligning technology with business objectives and ensuring excellence in IT delivery through secure, scalable solutions and strong relati...
Yesterday
Director, Medicare Regulatory Change Management
$118K - $219K *
Engage stakeholders by leading compliance initiatives and regulatory updates, ensuring successful implementation of standards across products. Drive collaboration among departments to navigate changes...
6 days ago
Clinical Director, Behavioral Health
$150K - $190K *
Champion a state-based mental health practice, leading operations and a diverse clinical team. Drive patient access and quality care for thousands of children, while maintaining a strong connection to...
Reposted 2 days ago
Director Implementation Success Leader, Coding Expert Remote
$150K - $175K *
Unlock potential by leading healthcare implementations as a trusted advisor. Drive client success through effective coding solutions, workflow integration, and change management, ensuring operational...
1 week ago
Director of Software Portfolio Strategy
$180K - $210K *
Lead the charge in shaping our software portfolio strategy, driving innovation across product management, engineering, and market insights to deliver scalable solutions that enhance customer value and...
3 weeks ago
Director, Billing & Collections (Financial Services/TPA Exp.)
$120K - $150K *
Drive operational excellence in billing and collections, ensuring accurate invoicing and compliance. Collaborate with cross-functional teams to enhance processes and minimize revenue leakage while lea...
2 weeks ago
$120K - $150K *
Accelerate progress at the intersection of systems administration and automation, as you collaborate with scrum teams to deploy scalable infrastructure, optimize cloud services, and enhance production...
Today
Senior Director of Growth – Salesforce Practice
$200K - $250K *
Accelerate federal growth by leading business development for Salesforce solutions, shaping opportunities and building industry relationships to enhance our public sector footprint through strategic p...
Today
$120K - $150K *
Innovate enterprise cybersecurity architectures ensuring compliance with federal standards, enhancing continuous monitoring, and facilitating collaboration across teams, while supporting mission-criti...
2 weeks ago
Director - Energy Regulatory Policy
$120K *
Elevate clean energy initiatives by driving strategic regulatory engagement and policy development across key Midwestern states. Collaborate with diverse stakeholders and mentor a talented team to ach...
2 weeks ago
Executive Director, RAPID Manufacturing Institute
$200K - $300K *
Transform the future of manufacturing by leading a visionary team to enhance process intensification and foster strategic partnerships, ensuring industry relevance, funding growth, and impactful initi...
Today
$90K - $120K *
Shape the future of IT capacity management by ensuring resources meet business demand in a regulated environment. Collaborate with teams to optimize performance, manage risks, and align strategies for...
4 weeks ago
$100K - $130K *
Champion growth with strategic marketing leadership, driving initiatives that enhance customer engagement, retention, and brand visibility across the full lifecycle. Lead a dynamic team to optimize re...
1 week ago
$96K - $110K *
Innovate with us to enhance applications using AI-native workflows. Join our collaborative team to implement and maintain high-quality solutions while continuously learning and growing in your softwar...
3 weeks ago
Account Principal, Work Transformation
$120K - $150K *
Pioneer transformational programs as a delivery leader, driving client value and managing strategic initiatives while ensuring delivery excellence across complex contracts. Utilize extensive experienc...
Yesterday
Senior Manager, IT PMO & Corporate Engineering
$162K - $205K *
Lead a high-performing team in Corporate Engineering, driving automation, optimizing SaaS platforms, and ensuring seamless identity and access management to enhance efficiency and security across a gr...
2 weeks ago
Director, Insights & Engagement
$90K - $120K *
Join a team that's dedicated to leveraging data and insights to enhance stakeholder engagement and drive impact across the organization. Lead the development of analytics strategies that inform crucia...
1 week ago
Senior Director of Program Management, Global Operations
$150K - $180K *
Lead impactful client engagements by managing complex drug substance and product development programs. Drive success through cross-functional teamwork, strategic oversight, and proactive client relati...
Reposted 5 days ago
$111K - $149K *
Join a team that's enhancing HR operations and optimizing HRIS solutions in a complex healthcare environment, driving data integrity, efficiency, and compliance to support overhauls in payroll, benefi...
3 weeks ago
Manager, Business Analysis - Strategic Business Solutions PMO
$95K - $125K *
Lead strategic analysis initiatives and process improvements, optimizing efficiency while collaborating with stakeholders. Drive decision-making through comprehensive documentation and support project...
1 week ago
$90K - $120K *
Accelerate technical excellence by designing and maintaining secure endpoint configurations in Windows and macOS environments, ensuring robust support for a federal agency's infrastructure and cyberse...
2 weeks ago
Lead Director, Software Development Engineering
$156K - $288K *
Drive software development solutions by leading cross-functional teams in creating and enhancing digital applications. Optimize user needs analysis to deliver high-quality software, ensuring performan...
3 days ago
Technical Enablement, Senior Manager
$115K - $145K *
Elevate technical expertise across teams by creating effective training programs. Collaborate cross-functionally to develop AI-driven content that enhances platform knowledge and drives measurable out...
1 week ago
What is the role of a Director, Information Systems?
A Director of Information Systems is responsible for overseeing the IT strategy of an organization, ensuring systems, infrastructures, and networks operate smoothly.
What qualifications do I need to be a Director, Information Systems?
Typical qualifications include a bachelor's or master's degree in IT or related fields and several years of experience.
What jobs are available on Ladders for Directors, Information Systems?
Ladders hosts a wide range of high-paying jobs for Directors of Information Systems. All jobs listed pay $100K or more per year.