Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$100K - $110K *

Lead the charge in expanding and optimizing a statewide clinical placement system, fostering partnerships with healthcare providers and educational institutions to enhance California's healthcare work...

California, USRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$90K - $110K *

Elevate your career by providing expert support in molecular diagnostics, driving product implementation, and fostering strong relationships with clinical laboratories to ensure successful adoption an...

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1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $259K *

Lead the charge in optimizing global drug safety operations, ensuring compliance and excellence in pharmacovigilance. Drive strategic initiatives, manage vendor relationships, and enhance processes to...

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5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

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3 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

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1 week ago

  •   5 - 7 years exp.  •   Business Services

$97K - $113K *

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2 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

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Palm Beach, FLRemote

2 weeks ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$500K+*

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Tennessee, USRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$119K - $134K *

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1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Join a dynamic team to lead the development of innovative Microsoft-based platforms, driving modernization and AI integration while ensuring robust, scalable, and secure solutions in a highly regulate...

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1 week ago

  •   8 - 10 years exp.  •   Healthcare

$210K - $250K *

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1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Unlock your potential as you drive product strategy and execution within our Clinical Content portfolio, collaborating with cross-functional teams to enhance healthcare delivery and maximize user expe...

Georgia, USRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$122K - $177K *

Lead coding operations and education initiatives to ensure compliance, accuracy, and optimal reimbursement across the organization. Manage staff training and oversee coding standards while collaborati...

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1 week ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

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2 days ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

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Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$169K - $282K *

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Reposted 4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$225K - $324K *

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1 week ago

  •   11 - 15 years exp.  •   Information Technology

$112K - $222K *

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Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$175K - $283K *

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United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$135K - $150K *

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2 days ago

  •   5 - 7 years exp.  •   Information Technology

$128K - $254K *

Drive the successful delivery of Phase I-IV clinical trials by leading cross-functional teams, managing project timelines, budgets, and quality standards while fostering strong client relationships an...

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Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$163K - $220K *

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Reposted 1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$180K - $220K *

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2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

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6 days ago

  •   8 - 10 years exp.  •   Healthcare

$159K - $239K *

Transform the future of people strategies by leading innovative initiatives that amplify field experiences and drive organizational effectiveness while building strong partnerships across leadership t...

Florida, USRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.