Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$80K - $100K *

Develop your career with flexible opportunities as a licensed clinical psychologist. Provide dedicated support to older adults through evidence-based therapy in a collaborative, remote setting. Contro...

Arkansas, USRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $94K *

Lead the development and execution of training programs while optimizing workflows to enhance provider experiences. Collaborate with stakeholders to ensure effective training delivery and continuous i...

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3 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Join a team that's redefining change management in healthcare. Support the adoption of innovative informatics solutions, ensuring seamless transitions and user readiness across the Veterans Health Adm...

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3 weeks ago

  •   5 - 7 years exp.  •   Business Services

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1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$220K - $250K *

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Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

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Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$170K - $190K *

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3 days ago

  •   5 - 7 years exp.  •   Healthcare

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3 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

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3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $220K *

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1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$124K - $211K *

Innovate clinical product strategies by analyzing market data and collaborating across departments. Drive product development and regulatory compliance while enhancing clinical initiatives to ensure c...

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5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

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Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$189K - $246K *

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San Diego, CARemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

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Harrisburg, PARemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$252K - $315K *

Drive innovation in interventional psychiatry by developing evidence-based programs and protocols. Collaborate with clinical teams to enhance patient outcomes and ensure compliance with regulatory sta...

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2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$225K - $250K *

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3 days ago

  •   8 - 10 years exp.  •   Healthcare

$107K - $166K *

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Springfield, OHRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$247K - $309K *

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6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

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Waltham, MARemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$76K - $199K *

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4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

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1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

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1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

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2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$101K - $152K *

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3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

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Chicago, ILRemote

1 month ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.