Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$100K - $120K *

Drive network expansion by engaging providers and negotiating contracts to enhance Medicare services. Collaborate with a remote team to ensure network adequacy and build strong relationships with heal...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $172K *

Join a team that's dedicated to enhancing clinical practices in healthcare. As a strategic advisor, you'll collaborate with internal teams and customers, driving education and best practices while ens...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $104K *

Lead strategic client relationships by managing complex needs, delivering tailored solutions, and driving long-term growth. Collaborate across teams to ensure high-quality outcomes and client satisfac...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Join a team that's driving strategic growth and profitability in healthcare solutions. Lead cross-functional initiatives, own P&L, and ensure client success while shaping market strategy and solution...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Healthcare

$210K - $250K *

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United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

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1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$133K - $191K *

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United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $192K *

Elevate telehealth access by providing evidence-based behavioral health care through clinical assessments and personalized treatment plans with a supportive multidisciplinary team in a fully virtual r...

New York, NYRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$71K - $97K *

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RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Lead the charge in delivering innovative telehealth psychotherapy for older adults. Collaborate within a supportive team while maintaining your own practice schedule, ensuring meaningful connections w...

Connecticut, USRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in delivering exceptional pharmacy services, ensuring medication safety and quality. Guide a team while enhancing patient care through management and innovation in pharmaceutical pract...

Bridgeport, CTRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$86K - $123K *

Join a team that's dedicated to optimizing project management processes and systems. This role supports the PMO by ensuring accurate documentation, training stakeholders, and maintaining governance st...

Gilbert, AZRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$85K - $100K *

Help us optimize Epic applications by leading projects, troubleshooting issues, and ensuring seamless integration. Collaborate with teams to enhance workflows and provide expert support, all while mai...

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4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Join a dynamic strategy team to analyze oncology and specialty care initiatives, building models and providing insights that guide leadership decisions across various commercial segments...

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Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$190K - $238K *

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3 days ago

  •   8 - 10 years exp.  •   Healthcare

$200K - $250K *

Empower your career through a transformative fellowship, gaining leadership skills and management experience while collaborating with senior executives to impact healthcare delivery and specialty prac...

Sacramento, CARemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in organizational change management for complex life sciences transformations, focusing on global Veeva CRM implementations. Drive strategy, execution, and stakeholder engagement acros...

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3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$190K - $230K *

Join a team that's driving innovation in biopharma partnerships. Leverage your expertise to identify and advance strategic opportunities, influence cross-functional decisions, and manage alliances tha...

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2 days ago

  •   8 - 10 years exp.  •   Business Services

$162K - $188K *

Accelerate progress at a pivotal organization by leading revenue strategies, managing key relationships, and enhancing brand visibility. Drive fundraising efforts to meet ambitious goals while fosteri...

Oakland, CARemote

1 week ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$145K - $160K *

Accelerate growth by leading strategic sales initiatives in the Ambulatory Surgery Center market. Build executive partnerships, drive customer satisfaction, and expand market share through innovative...

Texas, USRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $200K *

Join a dynamic team to design and implement secure EHR integrations, enhancing healthcare interoperability. Lead the integration of SMART on FHIR applications into clinical workflows while establishin...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$177K - $283K *

Unlock potential by leading pharmacokinetic modeling for early-stage drug development. Collaborate with cross-functional teams to enhance drug absorption, distribution, metabolism, and excretion (ADME...

United StatesRemote

6 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Drive the medical strategy by shaping partnerships and guiding evidence generation. Lead initiatives that connect clinical needs with business objectives, enhancing patient access and supporting innov...

CanadaRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$105K - $115K *

Join a team that's focused on diversifying paid media channels and optimizing conversion strategies. You'll lead initiatives across affiliate, programmatic, and social platforms to enhance member acqu...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Champion the analysis and reporting of clinical pathology data for nonclinical safety studies, collaborating with Study Directors and Anatomic Pathologists to ensure high-quality scientific outcomes i...

New York, NYRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.