Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
More
1
caret down

$65K - $130K *

Contribute to clinical trial success by leading risk management and central monitoring activities. Collaborate with cross-functional teams to ensure compliance with ICH GCP guidelines and enhance qual...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Engage a diverse medical affairs team to ensure effective Local Coverage Determinations and pricing, oversee comprehensive project management, and drive operational excellence while enhancing stakehol...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$146K - $196K *

Transform genomic insights into clinical applications by designing automated solutions and integrating AI/ML approaches. Collaborate with cross-functional teams to enhance variant curation and ensure...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Join a dynamic team to shape the future of AI governance, enhancing workflows and coordinating cross-functional reviews. Drive improvements in oversight processes while collaborating with senior leade...

Chattanooga, TNRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Elevate healthcare reimbursement processes by leading legal strategies on billing disputes and regulatory compliance. Collaborate with teams to create innovative solutions and build legal frameworks t...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$144K - $288K *

Transform your career by leading enterprise-scale AI/ML initiatives that enhance data engineering capabilities and operational excellence. Drive innovation, security, and compliance for impactful AI s...

Connecticut, USRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$245K - $265K *

Optimize partnerships with Medical Experts to enhance neurology care. Drive strategic insights and educational initiatives while collaborating across teams to influence business decisions and improve...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Lead the charge in integrating complex hospital data systems into Astra OS. Own end-to-end data pipelines, collaborate with customers, and design scalable solutions that enhance healthcare operations...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$163K - $245K *

Shape security architecture by designing robust frameworks across various tech domains. Collaborate with cross-functional teams to ensure comprehensive cybersecurity solutions aligned with business go...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$203K - $253K *

Strategize and lead patient advocacy and medical education initiatives, fostering collaboration with stakeholders to enhance patient engagement and inform Medical Affairs strategies. Drive impactful i...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Lead the management of privacy risks and regulatory compliance while providing expert guidance on AI-related legal issues to cross-functional teams in a dynamic healthcare environment. Drive privacy i...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Lead customer success programs from onboarding to adoption, ensuring smooth collaboration among engineering, product, and client teams. Drive accountability, maintain clarity, and deliver measurable v...

Pleasanton, CARemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Elevate lives by delivering evidence-based psychotherapy to older adults in a supportive, flexible remote environment. Collaborate with a dedicated team while managing your own schedule and focusing o...

Washington DC, USRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join us to lead the development and execution of clinical study designs, ensuring effective project management and collaboration across teams. Your expertise will drive the success of clinical trials...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Staffing

$100K - $120K *

Transform healthcare delivery by leading program initiatives that drive partner success in value-based care. Utilize data-driven strategies to manage launch processes, ensuring alignment across teams...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Shape the future of healthcare revenue integrity by ensuring compliance and optimizing revenue capture through strategic oversight and collaboration across departments, fostering a culture of accounta...

Los Angeles, CARemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Shape the future of healthcare by leading complex architectural and facility projects, ensuring optimal client service and regulatory compliance throughout all project phases while guiding multidiscip...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Technical Services

$140K - $186K *

Elevate your career by promoting clinical excellence in a dynamic Trauma Surgical ICU. Collaborate with nursing leadership to develop educational programs that enhance patient safety and staff compete...

Seattle, WARemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$106K - $147K *

Lead the charge in developing innovative software solutions by collaborating with cross-functional teams, shaping product roadmaps, and delivering high-quality user interfaces and APIs that enhance us...

Kentucky, USRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $153K *

Lead the charge in optimizing clinical and business information systems. Drive project management, enhance workflows, and mentor team members while ensuring effective technical solutions and support a...

Worcester, MARemote

4 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$130K - $150K *

Join a team that's dedicated to enhancing customer experiences by leading onboarding initiatives, managing cross-functional collaboration, and driving process improvements to ensure timely program lau...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$169K - $231K *

Champion strategic account growth by fostering relationships and driving behavior change in corporate accounts. Leverage market insights to meet revenue goals and enhance product utilization through c...

Texas, USRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$135K - $165K *

Pioneer operational excellence in Design leadership, managing workflows, prioritizing projects, and developing talent. Collaborate cross-functionally to enhance Design integration in AI-driven product...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $100K *

Join a team that's dedicated to delivering high-quality psychotherapy to older adults. Enjoy flexible scheduling, comprehensive support, and the opportunity to make a meaningful impact in a collaborat...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$108K - $196K *

Shape the future of healthcare by managing client relationships and optimizing clinical programs. Collaborate with teams to drive client success and ensure alignment with company goals, leveraging dat...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.