Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$175K - $210K *

Transform the landscape of emerging therapies by leading strategic clinical innovation, guiding development, and ensuring regulatory readiness for novel therapeutic solutions across early- and mid-sta...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$250K - $500K+*

Elevate risk management by leading enterprise risk, actuarial, and reinsurance strategies. Collaborate with senior leadership to ensure sound decision-making and governance, while protecting the balan...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Finance & Insurance

$110K - $130K *

Shape the market presence of Chorus by owning positioning, messaging, and launch governance. Collaborate with cross-functional teams to craft strategies that enhance product perception and drive insig...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Champion continuous improvement initiatives by optimizing processes and products across the organization. Lead cross-functional teams to enhance operational efficiency, quality, and customer experienc...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$73K - $130K *

Lead the charge in overseeing claims compliance activities, enhancing operational quality, and ensuring audit readiness. Collaborate cross-functionally to identify gaps, monitor KPIs, and drive improv...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$96K - $145K *

Transform service delivery for complex accounts by ensuring SLAs and KPIs are met. Lead governance, performance management, and continuous improvement initiatives while building trusted relationships...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$256K - $347K *

Lead the charge in ensuring optimal safety standards for Rare Disease products. Establish pharmacovigilance strategies, oversee safety profiles, and engage cross-functional teams to deliver critical t...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Advance your career by overseeing educational operations for Medical Imaging programs, ensuring compliance and high-quality delivery through blended and online modalities while leading a dedicated tea...

Reno, NVRemote

4 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$112K - $169K *

Help us enhance healthcare integration by designing and implementing HL7 interfaces for Perinatal Systems. Collaborate with clients and vendors to streamline hospital IT systems, ensuring efficient da...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Shape the future of health and wellness by providing clinical leadership, ensuring regulatory compliance, and driving quality improvement across communities to enhance resident-centered care and outco...

Wilmington, DERemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$107K - $199K *

Lead the charge in claims analysis by managing teams, analyzing data, and implementing solutions that enhance claims operations performance. Drive efficiency and quality improvements while fostering a...

Florida, USRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$195K - $245K *

Champion AI strategy and implementation in healthcare, leading a team to deliver measurable value. Drive business development, client engagement, and practice growth while shaping innovative solutions...

Chicago, ILRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$149K - $298K *

Lead strategic and operational initiatives for field clinical teams, ensuring compliance and effective trial support for TMVR programs while driving positive patient outcomes and team performance...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Lead the charge in managing workplace design and construction projects, ensuring operational readiness and accountability across multiple sites while optimizing budgets and vendor performance for succ...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$69K - $125K *

Join a dynamic team as a functional liaison, driving Medicare initiatives and enhancing project delivery. Collaborate across departments to analyze impacts, manage changes, and ensure successful imple...

Chicago, ILRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$129K - $177K *

Optimize strategic decisions by leading a team of actuaries to analyze complex financial data. Collaborate with stakeholders to enhance provider relationships and reporting, driving impactful solution...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $258K *

Unlock your potential as a Senior Engagement Manager, leading complex consulting projects for pharmaceutical clients. Drive strategic medical initiatives, foster client relationships, and mentor teams...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$71K - $102K *

Engage in quality assurance leadership for Prior Authorization reviews, ensuring compliance, accuracy, and efficiency. Oversee a team of auditors, drive improvement initiatives, and enhance provider a...

Florida, USRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$72K - $130K *

Unlock potential by leading initiatives that enhance behavioral health quality and reduce costs. Collaborate with diverse teams to implement innovative solutions, optimize provider performance, and im...

Phoenix, AZRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Pioneer in radiology innovation by enhancing clinical value and technology. Join a forward-thinking team that prioritizes high-quality patient care while driving improvements in service and operationa...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$238K - $311K *

Transform data governance by leading enterprise strategies, ensuring data quality, and driving AI readiness. Collaborate across teams to establish policies, enhance metadata platforms, and foster a cu...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$115K - $120K *

Transform client lives by delivering virtual counseling services, managing treatment plans, and maintaining a consistent caseload. Enjoy a stable schedule while making a meaningful impact in a support...

Farmington, NMRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $120K *

Join a team that's leveraging technology to enhance mental health access through telehealth. Provide comprehensive assessments and tailored treatment plans while collaborating with professionals to su...

Oakland, CARemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $240K *

Lead strategic relationships with influential optometrists and ophthalmologists, shaping the Presbyopia ecosystem through education and engagement. Drive insights and collaboration across medical, mar...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $100K *

Support the CEO Office as an Executive Assistant, facilitating smooth operations, managing schedules, and coordinating high-level events. Drive strategic initiatives and foster collaboration among pee...

California, USRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.