Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.
A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.
Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.
CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.
Clinical Specialist, Advanced Therapeutics- Cardiometabolic and MWL (Ambulatory), 40hr, Day
$101K - $181K *
Drive patient-centered clinical pharmacy services, optimizing outcomes through comprehensive medication reviews and targeted management programs. Engage in interdisciplinary collaboration and lead ini...
1 week ago
Associate Director, Programming
$164K - $213K *
Champion innovative programming solutions to enhance clinical studies, ensuring quality and compliance. Collaborate with cross-functional teams and lead programming strategies for assigned compounds...
6 days ago
Senior Director, Client Success
$180K - $225K *
Lead client experience strategy and team performance, driving financial success and long-term retention across a diverse account portfolio while collaborating with executive stakeholders to implement...
Reposted 3 days ago
Clinical Manager - Virtual Behavioural Medicine (VBM) and Inpatient Behavioural Neurology Unit (4W)
$122K - $153K *
Transform patient care by leading innovative programs in Virtual Behavioural Medicine and Inpatient Behavioural Neurology. Drive operational excellence and quality improvement while supporting a dedic...
3 days ago
Senior Quality Operations Specialist, Audit
$74K - $98K *
Champion regulatory audit excellence by leading PACE audits, ensuring compliance, and driving cross-functional collaboration to enhance operational readiness and continuous improvement across the orga...
2 weeks ago
Senior Director, Risk & Compliance Business Partners R&D
$195K - $325K *
Elevate the Risk & Compliance strategy for R&D, leading a team to foster a risk-aware culture, manage budgets, and engage with stakeholders to ensure effective cyber risk management across GSK's resea...
Reposted yesterday
Principal Enterprise Cloud Architect
$159K - $265K *
Join a team that's leading the design and optimization of multi-cloud infrastructure. Drive cloud adoption and innovation while ensuring scalability, security, and cost-effectiveness across Azure, AWS...
1 week ago
$110K - $130K *
Manage and lead field-based medical teams, ensuring client delivery and team performance while fostering scientific engagement and program growth. Collaborate with cross-functional teams to achieve st...
3 weeks ago
$122K - $203K *
Empower teams by leading data governance initiatives, enhancing data quality, and fostering collaboration across business domains. Drive operational excellence and ensure compliance while developing a...
1 week ago
Revenue Cycle Management Transformation Manager
$78K - $113K *
Join us in transforming Revenue Cycle Management by leveraging analytical skills to enhance operational excellence across various RCM functions, driving process improvements and supporting financial p...
1 week ago
Sr. Trial Manager, Early Development, Oncology
$92K - $148K *
Unlock potential by leading clinical trials in oncology, ensuring compliance and quality data management. Collaborate with cross-functional teams to drive project success from start-up to closeout, wh...
6 days ago
Sr. Director of Machine Learning
$175K - $210K *
Champion the development and strategy of cutting-edge AI services, overseeing a dynamic team of ML engineers and scientists to deliver impactful, reliable, and clinically sound solutions that enhance...
3 weeks ago
Director, Diagnosis-Related Group Validation (DRGV)
$125K - $150K *
Unlock your potential by leading the development of innovative DRGV services, enhancing billing and coding optimization. Collaborate across teams to create scalable solutions that drive operational ex...
1 week ago
(Senior) Patient Safety Physician, Medical Safety Physician - Inflammation (Remote)
$265K - $397K *
Play a key role in global pharmacovigilance risk management activities, overseeing safety strategies for marketed and investigational compounds while leading cross-functional teams and ensuring compli...
3 weeks ago
Sr. Manager, Content and Thought Leadership
$130K - $160K *
Drive the evolution of a comprehensive content strategy, ensuring alignment across channels to enhance brand authority and trust. Lead editorial governance, manage content operations, and foster cross...
Reposted 4 days ago
General Counsel & Chief Commercial Officer
$240K - $280K *
Join a dynamic team to lead enterprise contract negotiations, pricing strategies, and partnerships for an innovative AI platform. Drive commercial success while overseeing legal operations globally, e...
1 week ago
Transformation Program Manager (Hybrid WI)
$88K - $105K *
Lead transformative initiatives by guiding strategy deployment and process improvements. Collaborate with leadership to empower teams, enhance care delivery, and drive organizational excellence throug...
3 weeks ago
Lead, Customer Experience Research
$119K - $186K *
Help us elevate customer experiences by leading complex research initiatives that inform strategic decisions. You'll drive insights using qualitative and quantitative methods while mentoring a team in...
Reposted 1 week ago
Medical Director, Occupational Health & Workers' Compensation Managed Care
$300K *
Elevate healthcare delivery by leading a dedicated team in clinical evaluations, ensuring best practices while providing client-facing support and expertise in medical claims, regulations, and emergin...
Reposted 1 week ago
$100K - $120K *
Lead the charge in enhancing rehabilitation operations across multiple facilities. Drive clinical excellence, manage staff, and ensure compliance while fostering a supportive environment for both pati...
2 weeks ago
Licensed Clinical Social Worker (LCSW) - Behavioral Health - Hybrid
$90K - $93K *
Join a dynamic team providing essential behavioral health support, addressing member needs through personalized interventions, referrals, and collaborative care to enhance overall mental health and we...
4 weeks ago
Transaction Management Director - Healthcare
$175K - $220K *
Shape the future of healthcare real estate by leading a dynamic transaction management team. Oversee negotiations, staff development, and strategic planning to drive client success and enhance operati...
2 days ago
Director Of Sales, Community Health Centers, East
$145K - $155K *
Pioneer strategic growth in healthcare by engaging C-suite executives, driving partnerships, and expanding market share within Community Health Centers across the Eastern U.S. This consultative role d...
2 weeks ago
Case Manager RN Supervisor - Remote Metro Chicago
$80K - $95K *
Drive the operations of case management with a focus on quality service and leadership. Leverage your clinical experience and supervisory skills to enhance team performance, ensuring efficient managem...
Reposted 1 week ago
Senior Medical Science Liaison - West
$130K - $155K *
Engage with key opinion leaders and stakeholders to advance scientific exchange and support the NGN-401 program in Rett syndrome. Collaborate across teams to provide medical insights and drive strateg...
1 week ago
What is a Chief Clinical Officer?
A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.
What does a Chief Clinical Officer do?
A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.
What qualifications are usually required for CCO jobs?
Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.
Where do Chief Clinical Officers work?
Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.
How can I find Chief Clinical Officer jobs paying $100,000 or more?
Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.