Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$164K - $213K *

Champion innovative programming solutions to enhance clinical studies, ensuring quality and compliance. Collaborate with cross-functional teams and lead programming strategies for assigned compounds...

New Jersey, USRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $225K *

Lead client experience strategy and team performance, driving financial success and long-term retention across a diverse account portfolio while collaborating with executive stakeholders to implement...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Healthcare

$122K - $153K *

Transform patient care by leading innovative programs in Virtual Behavioural Medicine and Inpatient Behavioural Neurology. Drive operational excellence and quality improvement while supporting a dedic...

Toronto, ONRemote

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$74K - $98K *

Champion regulatory audit excellence by leading PACE audits, ensuring compliance, and driving cross-functional collaboration to enhance operational readiness and continuous improvement across the orga...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$195K - $325K *

Elevate the Risk & Compliance strategy for R&D, leading a team to foster a risk-aware culture, manage budgets, and engage with stakeholders to ensure effective cyber risk management across GSK's resea...

Philadelphia, PARemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$159K - $265K *

Join a team that's leading the design and optimization of multi-cloud infrastructure. Drive cloud adoption and innovation while ensuring scalability, security, and cost-effectiveness across Azure, AWS...

Arizona, USRemote

1 week ago

  •   11 - 15 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Manage and lead field-based medical teams, ensuring client delivery and team performance while fostering scientific engagement and program growth. Collaborate with cross-functional teams to achieve st...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$122K - $203K *

Empower teams by leading data governance initiatives, enhancing data quality, and fostering collaboration across business domains. Drive operational excellence and ensure compliance while developing a...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$78K - $113K *

Join us in transforming Revenue Cycle Management by leveraging analytical skills to enhance operational excellence across various RCM functions, driving process improvements and supporting financial p...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$92K - $148K *

Unlock potential by leading clinical trials in oncology, ensuring compliance and quality data management. Collaborate with cross-functional teams to drive project success from start-up to closeout, wh...

Titusville, NJRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Champion the development and strategy of cutting-edge AI services, overseeing a dynamic team of ML engineers and scientists to deliver impactful, reliable, and clinically sound solutions that enhance...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$125K - $150K *

Unlock your potential by leading the development of innovative DRGV services, enhancing billing and coding optimization. Collaborate across teams to create scalable solutions that drive operational ex...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$265K - $397K *

Play a key role in global pharmacovigilance risk management activities, overseeing safety strategies for marketed and investigational compounds while leading cross-functional teams and ensuring compli...

New York, NYRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Drive the evolution of a comprehensive content strategy, ensuring alignment across channels to enhance brand authority and trust. Lead editorial governance, manage content operations, and foster cross...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Healthcare

$240K - $280K *

Join a dynamic team to lead enterprise contract negotiations, pricing strategies, and partnerships for an innovative AI platform. Drive commercial success while overseeing legal operations globally, e...

Washington, USRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$88K - $105K *

Lead transformative initiatives by guiding strategy deployment and process improvements. Collaborate with leadership to empower teams, enhance care delivery, and drive organizational excellence throug...

Wisconsin, USRemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$119K - $186K *

Help us elevate customer experiences by leading complex research initiatives that inform strategic decisions. You'll drive insights using qualitative and quantitative methods while mentoring a team in...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$300K *

Elevate healthcare delivery by leading a dedicated team in clinical evaluations, ensuring best practices while providing client-facing support and expertise in medical claims, regulations, and emergin...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Lead the charge in enhancing rehabilitation operations across multiple facilities. Drive clinical excellence, manage staff, and ensure compliance while fostering a supportive environment for both pati...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $93K *

Join a dynamic team providing essential behavioral health support, addressing member needs through personalized interventions, referrals, and collaborative care to enhance overall mental health and we...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$175K - $220K *

Shape the future of healthcare real estate by leading a dynamic transaction management team. Oversee negotiations, staff development, and strategic planning to drive client success and enhance operati...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$145K - $155K *

Pioneer strategic growth in healthcare by engaging C-suite executives, driving partnerships, and expanding market share within Community Health Centers across the Eastern U.S. This consultative role d...

Maine, USRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive the operations of case management with a focus on quality service and leadership. Leverage your clinical experience and supervisory skills to enhance team performance, ensuring efficient managem...

Downers Grove, ILRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Staffing

$130K - $155K *

Engage with key opinion leaders and stakeholders to advance scientific exchange and support the NGN-401 program in Rett syndrome. Collaborate across teams to provide medical insights and drive strateg...

New York, NYRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$162K - $271K *

Transform patient access and support by managing the entire journey from enrollment to follow-up. Collaborate with patients, providers, and payers to ensure seamless reimbursement and care coordinatio...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.