Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$125K - $150K *

Drive strategic growth and retention by managing high-value enterprise accounts, fostering executive relationships, and leading contract negotiations to align client objectives with innovative solutio...

Minneapolis, MNRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$177K - $242K *

Advance the future of gene therapy by leading CMC strategy and operations. Collaborate across teams to ensure successful development from early stages to commercialization, while managing regulatory s...

New Jersey, USRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $173K *

Join a team that's redefining AI-driven quality and performance operations. You'll build systems that enhance frontline team effectiveness and AI agent performance, ensuring impactful coaching and fee...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$105K - $130K *

Join a team that's dedicated to transforming the future of healthcare finance. Collaborate with cross-functional teams to enhance service delivery and drive innovative solutions that empower clients a...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $94K *

Optimize talent acquisition by partnering with clinical leadership to recruit licensed mental health therapists. Drive the full-cycle recruiting process, ensuring an exceptional candidate experience w...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Lead the charge in enhancing customer support by managing Tier 3 Support and Support Engineering teams. Drive technical resolutions, streamline escalations, and foster team development within a dynami...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by joining a dynamic Clinical Oncology Team, where you'll leverage your oncology and genomics expertise to enhance point-of-care products, drive clinical workflows, and support person...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$89K - $121K *

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Kentucky, USRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$182K - $250K *

Champion market development strategies to enhance our presence in CMS and HHS. Leverage your expertise to build relationships, identify opportunities, and drive impactful outcomes in federal health IT...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $200K *

Join a dynamic team to drive employer strategy and cultivate relationships with corporate benefits executives, enhancing the adoption of innovative Virtual Care solutions in a complex sales environmen...

Minneapolis, MNRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$79K - $105K *

Shape the future of patient care by coordinating high-quality, cost-effective services. Utilize your clinical expertise to advocate for members, ensuring appropriate care transitions and fostering col...

Hopewell, NJRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$165K - $185K *

Join a team that's shaping strategic direction and driving growth across multi-account projects in medical affairs. In this senior leadership role, you'll enhance client relationships, develop teams...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$68K - $103K *

Support the mental health team by conducting assessments, implementing crisis interventions, and ensuring high-quality care for patients in a dynamic telepsychiatry setting. Collaborate effectively wi...

Charlotte, NCRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Manage customer success, implementation, and support to drive retention and expansion. Own metrics, diagnose churn, and enhance onboarding. Lead a team to create a seamless customer journey and ensure...

New York, NYRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$179K - $280K *

Unlock potential by driving strategic revenue cycle performance and enhancing client partnerships. Lead initiatives across Self-Pay and Patient Financial Experience, leveraging data to influence decis...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $147K *

Shape your career by leading data integration initiatives that drive enterprise-wide consistency and governance. Collaborate with stakeholders to deliver trusted, scalable data products while ensuring...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$248K - $373K *

Play a key role in enhancing clinical quality for Veterans by overseeing community care services, collaborating with internal teams, and ensuring compliance with healthcare standards and regulations t...

Eden Prairie, MNRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $110K *

Drive client success by managing small to medium accounts, enhancing engagement, and leveraging data insights to improve health outcomes and revenue growth. Collaborate with teams to implement solutio...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Unlock your potential by leading a high-performing sales team in precision oncology. Drive strategic initiatives, foster cross-functional collaboration, and enhance patient care through innovative sal...

Philadelphia, PARemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $200K *

Drive the enterprise AI architecture for healthcare solutions, ensuring compliance and governance. Collaborate with cross-functional teams to establish standards and best practices for LLM application...

Illinois, USRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$76K - $199K *

Join a team that's driving innovation in Neuroscience by promoting breakthrough therapies. Engage with healthcare professionals to enhance sales and build lasting relationships while utilizing digital...

California, USRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $178K *

Optimize biosample operations in clinical trials, ensuring quality and compliance while collaborating with cross-functional teams to enhance sample management and drive innovation in biosampling strat...

Boston, MARemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $137K *

Drive impactful solutions by configuring and supporting Epic EHR applications, enhancing patient care and provider workflows. Collaborate with members to ensure quality outcomes and efficient integrat...

Oregon, USRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$76K - $105K *

Elevate patient care by joining a dynamic team of licensed therapists dedicated to clinical excellence and flexible work environments, ensuring a strong work/life balance and full administrative suppo...

Washington, USRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Lead the charge in delivering exceptional tele-neurology care through 7 monthly shifts, enhancing patient outcomes while collaborating with a dedicated team in a supportive, flexible remote environmen...

Nashville, TNRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.