Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$115K - $120K *

Elevate clinical care by guiding a team of therapists in a virtual setting. Shape treatment quality and ensure ethical standards while delivering effective therapy services across Montana. Join us in...

Plentywood, MTRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $120K *

Advance mental health support by providing telehealth therapy to clients across Kansas. Engage in virtual sessions, assessments, and treatment planning to help adults navigate emotional challenges and...

Kansas City, KSRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $120K *

Help us deliver exceptional counseling services while managing your own caseload and contributing to team discussions. This role is ideal for an experienced LCPC who thrives in a collaborative, remote...

Maryland, USRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $120K *

Unlock your potential in a full-time telehealth role, providing essential therapy to adults. Manage a diverse caseload, ensuring quality care and documentation while working independently in a support...

Wichita, KSRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $130K *

Lead the charge in overseeing clinical trial management, ensuring compliance, data integrity, and patient safety. Collaborate with cross-functional teams to meet project milestones and manage risks ef...

New Jersey, USRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $130K *

Unlock potential by leading clinical trial initiatives, ensuring adherence to safety, compliance, and quality standards. Collaborate with cross-functional teams to manage all phases of clinical resear...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a team that's dedicated to ensuring the success of clinical trials through effective site management, compliance oversight, and risk mitigation strategies, all while fostering collaboration acros...

Wyoming, USRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive operational excellence by overseeing program management activities, supervising a dedicated team, and ensuring adherence to policies and procedures. Collaborate with stakeholders to enhance effi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $130K *

Join a team focused on excellence in clinical trial management, overseeing site interactions, ensuring data integrity, and driving compliance. You'll lead efforts in patient safety, recruitment, and d...

Massachusetts, USRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Champion a transformative product vision, leading cross-functional teams to drive strategic outcomes in a dynamic digital health environment. Shape the future of patient care and client experience whi...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$70K - $126K *

Empower strategic initiatives by managing complex projects, enhancing processes, and fostering cross-functional relationships. Lead teams to execute plans effectively while ensuring alignment with org...

Missouri, USRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$108K - $156K *

Empower your career by leading revenue analytics, overseeing financial analysis, and enhancing payer contract strategies. Collaborate with cross-functional teams to optimize reimbursement and drive or...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$126K - $174K *

Drive transformation by leading complex, cross-functional projects that solve strategic business challenges. Collaborate with senior leaders to deliver data-driven insights and compelling presentation...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$108K - $130K *

Transform security governance by leading operational excellence, managing risks, and ensuring compliance. Drive remediation efforts and foster strong relationships with stakeholders while delivering i...

Arkansas, USRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Elevate organizational impact by driving strategic initiatives and fostering cross-functional alignment. Collaborate with global teams to ensure seamless execution of key projects while enhancing comp...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Unlock potential by delivering expert medical information support to healthcare professionals, ensuring safe product use through timely, evidence-based responses and effective communication across mul...

Overland Park, KSRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$119K - $186K *

Advance your career by providing strategic legal counsel on data governance, privacy, and cybersecurity within a dynamic healthcare environment. Collaborate with cross-functional teams to drive compli...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$140K - $183K *

Empower clinical excellence by leading educational initiatives in Emergency Services, enhancing staff competency and patient care through evidence-based practices and collaboration with nursing leader...

Seattle, WARemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$223K - $313K *

Collaborate with a dedicated team of physicians to ensure high-quality inpatient care through clinical expertise, thorough reviews, and utilization management. Advance patient outcomes by utilizing st...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$98K - $164K *

Champion client success by leading post-sale implementations and ensuring ongoing account performance. Collaborate with cross-functional teams to translate client needs into actionable insights, drivi...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$112K - $222K *

Advance clinical site management with leadership to optimize study operations and deliverables. Establish strong sponsor relationships while overseeing project activities and motivating remote teams t...

Durham, NCRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Shape the future of cybersecurity by overseeing a zero trust security framework. Drive strategic initiatives across identity, data protection, and network security, collaborating with leadership to en...

Phoenix, AZRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Drive security excellence by managing identity access, external testing, and compliance processes. Collaborate with teams to enhance AWS security and develop scalable policies, ensuring robust protect...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$91K - $163K *

Join a team that's dedicated to improving healthcare outcomes through clinical review and collaboration. You'll engage in appeals and grievances processes, working closely with medical directors and p...

Minnetonka, MNRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$75K - $90K *

Transform your career with impactful auditing and training roles in risk adjustment. Collaborate with management to enhance coding compliance, drive performance improvement, and foster a culture of ex...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.