Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

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$145K - $165K *

Lead the charge in enhancing marketing technology platforms to optimize customer engagement and journey orchestration. Collaborate with cross-functional teams to deliver reliable solutions and improve...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Join a team that's dedicated to advancing clinical data programming in oncology. Leverage your expertise to develop SAS programs, ensure data integrity, and collaborate with cross-functional teams to...

New Jersey, USRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$190K - $225K *

Shape the future of healthcare by driving strategic KOL engagement and insight generation in rare neurology. Collaborate with thought leaders to influence brand strategy and enhance patient outcomes t...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Innovate clinical quality systems for scalable care delivery, ensuring standards meet payer expectations and driving measurable performance improvements across independent health providers...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

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Topeka, KSRemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $125K *

Manage a team of medical writers to develop impactful scientific content, ensuring accuracy and compliance. Collaborate with clients and cross-functional teams to drive medical strategies and delivera...

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Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $90K *

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New York, NYRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

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Raleigh, NCRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

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Mckinney, TXRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Unlock your potential by driving enterprise growth in healthcare. Join a dynamic team focused on building relationships with health systems and provider organizations, leveraging a robust support engi...

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6 days ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $245K *

Drive strategic engagement with Key Opinion Leaders in rare neurological diseases, leading a national team. Manage relationships, synthesize insights, and guide thought leader strategies to influence...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$145K - $190K *

Join a team dedicated to advancing oncology clinical trials. In this role, you’ll manage global studies, oversee vendors, collaborate with multi-disciplinary teams, and ensure compliance with regulato...

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Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$92K - $167K *

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Chicago, ILRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $160K *

Shape the future of AI governance by leading a dedicated team to drive responsible adoption and implementation of AI solutions, guiding stakeholders towards high-value opportunities while ensuring com...

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3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$125K - $150K *

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Reposted 5 days ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $90K *

Advance quality assurance initiatives and optimize workflows in a remote healthcare contact center. Collaborate cross-functionally to enhance compliance, improve patient outcomes, and drive continuous...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$215K - $289K *

Lead the charge in driving legal strategy and contract negotiations across all business units, ensuring compliance and supporting revenue growth through effective collaboration with sales, finance, an...

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3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$134K - $230K *

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Minnetonka, MNRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

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3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Drive the advancement of enterprise Identity, Credential, and Access Management (ICAM) capabilities in contested environments, leading technical studies and architectural development to enhance operat...

Washington, DCRemote

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$102K - $184K *

Optimize patient care by collaborating with healthcare teams to enhance medication utilization and quality outcomes. Drive strategic initiatives in value-based care while mentoring future pharmacists...

Houston, TXRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$170K - $180K *

Drive compliance and legal strategy in a pivotal role, advising leadership while managing risk, privacy, and governance across global operations. Leverage AI tools for efficiency and effectiveness in...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$170K - $200K *

Lead cross-functional integration of data, analytics, evaluation, and governance to enhance healthcare AI products. Drive roadmap ownership, optimize workflows, ensure data quality, and foster collabo...

Palo Alto, CARemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Unlock your potential as a key player in optimizing EPIC applications, leading complex projects, and enhancing user experience in healthcare IT. Collaborate with stakeholders to deliver innovative sol...

Chicago, ILRemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Drive operational excellence by leading global partnerships and enhancing efficiency. Collaborate with teams to achieve strategic goals, support change management, and ensure accountability in meeting...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.