Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
More
1
caret down

$100K - $120K *

Join a team that's driving business development across a diverse portfolio, managing accounts, generating leads, and closing sales. You'll engage with clients to deliver customized solutions while ach...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$174K - $374K *

Lead the charge in transforming healthcare by overseeing medical policy implementation and enhancing clinical programs. Collaborate with teams to ensure quality assurance and effective utilization rev...

Illinois, USRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$143K - $243K *

Champion innovative clinical strategies in specialty pharmacy, overseeing services and solutions to enhance client value and outcomes. Collaborate with cross-functional teams to drive program performa...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $258K *

Elevate your career by leading strategic initiatives in Medical and Scientific Affairs. Drive portfolio governance, enhance operational excellence, and foster cross-functional collaboration to deliver...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a team that's redefining clinical workflows by serving as a trusted clinical voice, collaborating across departments to enhance product development and ensure successful implementation of cardiov...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$193K - $308K *

Join a team that's redefining statistical leadership in clinical research. Drive innovative study designs, enhance drug development effectiveness, and influence critical decisions through data-driven...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Advance global service delivery by managing offshore partnerships, ensuring performance excellence, and driving operational improvements across teams to enhance productivity and quality outcomes...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Support clinical research initiatives by providing expert medical and scientific guidance on medical products, trials, and regulatory compliance, ensuring effective collaboration with DoD and FDA stak...

Bethesda, MDRemote

2 days ago

  •   Less than 5 years exp.  •   Business Services

$104K - $143K *

Unlock your potential by supporting complex, cross-functional initiatives. Engage in strategic problem-solving and data analysis to drive impactful business recommendations while collaborating with di...

New York, USRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$113K - $197K *

Lead regulatory and compliance oversight for Operations, ensuring accuracy and efficiency. Collaborate with enterprise partners to enhance operational processes, implement automation, and drive contin...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in credentialing excellence by managing a remote team that ensures timely hospital privileges for healthcare providers, enhancing patient access to critical specialty care across the n...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$206K - $413K *

Join our team to lead in Physical Medicine and Rehabilitation, providing oversight, improving utilization, and guiding medical policy. Collaborate with staff and external partners to enhance healthcar...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$190K - $220K *

Champion operational excellence by overseeing centralized care delivery support services. Drive performance improvements, optimize workflows, and enhance patient access while collaborating with clinic...

Atlanta, GARemote

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$160K - $200K *

Join a dynamic team to lead the strategy and delivery of innovative reporting and analytics solutions that enhance client value and patient services. Drive insights, foster collaboration, and elevate...

Mason, OHRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$108K - $130K *

Drive program delivery across multiple products, ensuring timely outcomes by managing risks, dependencies, and stakeholder priorities. Collaborate cross-functionally to maintain accurate project data...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $150K *

Unlock operational excellence by leading multi-site Ambulatory Surgery Centers. Drive growth strategies, optimize performance, and foster strong partnerships with physician leaders while managing sign...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$134K - $219K *

Lead clinical laboratory operations for precision medicine projects, ensuring timely deliverables and risk management across therapeutic areas. Collaborate with cross-functional teams to support clini...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock potential by fostering client relationships and expanding service offerings, enhancing market presence in the Consumer, Retail, and Logistics domain through innovative solutions and collaborati...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$150K - $180K *

Champion patient-centered outcomes by leading scientific research and strategic initiatives. Direct clinical outcome assessment projects, cultivate client relationships, and drive revenue growth while...

Boston, MARemote

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $104K *

Transform your career by providing essential behavioral health support, developing care plans, and collaborating with care teams to address member needs in a hybrid role that balances virtual and comm...

Massachusetts, USRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$250K - $250K+*

Empower your career by providing strategic financial leadership for global growth, building a world-class finance function while driving value for stakeholders and investors. Collaborate remotely with...

New York, NYRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$136K - $171K *

Pioneer clinical trial excellence by leading operational planning and execution. Collaborate cross-functionally to ensure compliance, quality, and timely delivery of clinical studies while mentoring j...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$173K *

Drive strategic financial leadership in a growing nonprofit, enhancing operational effectiveness and fostering partnerships to advance health justice initiatives across communities...

Chicago, ILRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Empower organizational growth by leading development initiatives that enhance team effectiveness, drive change, and align workforce capabilities with business objectives. Collaborate across functions...

Laval, QCRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $135K *

Transform compliance oversight in the DME order-to-payment lifecycle. Lead audits, analyze data, and coordinate payer audits while developing practical controls and reporting to enhance revenue integr...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.