Chief Clinical Officer (CCO) Jobs

Explore Chief Clinical Officer jobs on Ladders, where professionals can find vetted opportunities paying $100,000 or more. Chief Clinical Officers guide clinical strategy and help healthcare organizations deliver safe, effective, high-quality care. They partner with executive teams and clinical leaders to align patient outcomes, operational priorities, and organizational goals.

What Does a Chief Clinical Officer Do?

A CCO provides senior-level oversight of clinical services and helps shape care delivery across a hospital, health system, medical group, or other healthcare organization. Responsibilities may include setting clinical standards, advancing quality and patient safety, supporting regulatory compliance, and using performance data to identify opportunities for improvement. CCOs often collaborate with physicians, nurses, administrators, and finance and operations teams.

Common CCO Responsibilities

  • Develop and implement clinical strategy aligned with organizational priorities.
  • Monitor quality, safety, patient experience, and clinical performance.
  • Lead initiatives that improve care coordination and clinical outcomes.
  • Support accreditation, regulatory readiness, and evidence-based practice.
  • Build alignment among medical staff, care teams, and executive leadership.
  • Guide clinical operations, resource planning, and service-line development.

Qualifications for Chief Clinical Officer Roles

Requirements vary by employer and setting. Many CCO positions call for a clinical degree and an active or previously held professional license, along with substantial experience in healthcare leadership. Employers may seek a physician executive or another experienced clinical leader with a record of improving quality, leading multidisciplinary teams, and managing complex organizational change. Business, health administration, or leadership training can also be valuable.

Find Chief Clinical Officer Jobs

CCO opportunities may be available at hospitals, health systems, specialty-care organizations, and other healthcare providers. Browse vetted Chief Clinical Officer openings on Ladders and explore senior healthcare leadership roles with compensation of $100,000 or more. Compare responsibilities and qualifications to identify positions that fit your experience and career goals.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
More
1
caret down

$100K - $130K *

Lead the charge in enhancing member care as you coach and develop clinical teams, oversee daily operations, and ensure compliance with regulatory standards while driving quality improvements and opera...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $200K *

Join a team that's shaping the future of healthcare marketing by leading strategy and execution across a diverse portfolio. Drive demand generation, brand management, and market insights to position o...

Burlington, MARemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$100K - $231K *

Advance your career by leading healthcare analytics initiatives that transform data into impactful insights, drive performance, and enhance decision-making across departments while fostering innovatio...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$70K - $126K *

Manage complex HEDIS audit workstreams and ensure compliance with regulations. Provide expert guidance on audit readiness, interpret regulatory requirements, and develop controls to support accurate s...

Missouri, USRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$174K - $374K *

Lead the Medicare Appeals team, overseeing daily operations and ensuring compliance. Collaborate with healthcare professionals to enhance efficiency and provide expert guidance on Medicare policies wh...

Connecticut, USRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Lead the charge in optimizing operations for a virtual clinic, enhancing service delivery and patient experience. Drive strategic initiatives and implement data-driven improvements to support families...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$117K - $161K *

Join a team that's redefining member engagement through advanced analytics and strategic leadership. Drive analytics strategy, mentor engineers, and enhance conversational experiences across innovativ...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Transform customer success and support by leading a dynamic team to enhance retention and expansion strategies. Collaborate with executives to build infrastructure and drive growth for 2,100+ accounts...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Legal & Accounting

$181K - $200K *

Champion transformative call center operations by leading strategic outreach, workforce management, and capacity planning. Drive efficiency and quality through innovative automation and AI solutions w...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $165K *

Drive the development of a centralized data warehouse for biomedical research, enhancing data integration and functionality. Collaborate with teams to optimize data pipelines and support national rese...

Connecticut, USRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$160K - $200K *

Shape the future of market access strategy by integrating payer, provider, and patient perspectives. Lead cross-functional teams to develop impactful strategies that enhance therapy positioning and su...

Philadelphia, PARemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$91K - $101K *

Elevate your career by leading a dedicated team to ensure high-quality resident care in a collaborative environment. Drive operational excellence while blending healthcare and hospitality for optimal...

Spring Park, MNRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$160K - $190K *

Empower your career by partnering with the Science Leadership Team to drive strategic initiatives, enhance operational effectiveness, and translate scientific vision into impactful outcomes across div...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$207K - $392K *

Oversee provider network strategy and contracting activities, driving growth and operational excellence. Lead negotiations, evaluate costs, and support market expansion initiatives while ensuring alig...

Florida, USRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Lead cloud architecture and platform engineering, balancing strategic vision with hands-on technical execution. Drive team growth, ensure compliance, and enhance infrastructure for secure healthcare s...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$261K - $346K *

Lead the charge in clinical pharmacology strategies for rare disease and oncology programs, driving innovative solutions, study designs, and regulatory interactions to expedite drug development and im...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$89K - $148K *

Drive your career with impactful consulting in healthcare, enhancing operational efficiency and financial performance for provider organizations through data analysis and project management...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Business Services

$177K - $338K *

Help us advance women's health through innovative clinical trial strategies, where you will conduct, support, and report on global studies for cutting-edge compounds, ensuring adherence to regulatory...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$72K - $122K *

Join a dynamic team to support clinical systems and enhance user workflows. You'll analyze needs, design/testing systems, and train personnel while coordinating with clinical staff and ensuring effect...

New Bedford, MARemote

4 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Deliver comprehensive oversight and guidance for clinical trial monitoring, ensuring compliance and quality. Collaborate with cross-functional teams to address site issues, enhance recruitment, and ma...

Boston, MARemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive operational excellence in referral management by leading a dynamic team, optimizing processes, and enhancing patient access across multiple service lines. Collaborate cross-functionally to ensur...

North Carolina, USRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Join a team that's driving business development across a diverse portfolio, managing accounts, generating leads, and closing sales. You'll engage with clients to deliver customized solutions while ach...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$174K - $374K *

Lead the charge in transforming healthcare by overseeing medical policy implementation and enhancing clinical programs. Collaborate with teams to ensure quality assurance and effective utilization rev...

Illinois, USRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$143K - $243K *

Champion innovative clinical strategies in specialty pharmacy, overseeing services and solutions to enhance client value and outcomes. Collaborate with cross-functional teams to drive program performa...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $258K *

Elevate your career by leading strategic initiatives in Medical and Scientific Affairs. Drive portfolio governance, enhance operational excellence, and foster cross-functional collaboration to deliver...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What is a Chief Clinical Officer?question toggle

    A Chief Clinical Officer is an executive who oversees clinical strategy and helps ensure that an organization delivers safe, effective, high-quality care. The role often connects clinical teams with executive leadership.

  • What does a Chief Clinical Officer do?question toggle

    A CCO commonly leads clinical quality and safety initiatives, sets care standards, supports regulatory compliance, reviews performance data, and works with clinical and operational leaders to improve care delivery.

  • What qualifications are usually required for CCO jobs?question toggle

    Requirements depend on the organization. Employers often look for a clinical degree, relevant licensure or clinical background, and extensive leadership experience in healthcare. Some roles favor physician executives or candidates with experience in health administration.

  • Where do Chief Clinical Officers work?question toggle

    Chief Clinical Officers may work for hospitals, health systems, medical groups, specialty-care providers, and other healthcare organizations with complex clinical operations.

  • How can I find Chief Clinical Officer jobs paying $100,000 or more?question toggle

    Browse Ladders for vetted senior healthcare leadership opportunities, review each listing’s requirements and compensation details, and focus your search on roles that match your clinical and executive experience.