Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Analytics Engineer Jobs in Missouri

Sort By: Relevance

$89K - $107K *

Join a team that's transforming healthcare through data-driven insights. As a Senior Medical Economics Analyst, you'll lead analytics initiatives, mentor a team, and collaborate with leaders to enhanc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$121K - $191K *

Join the team to design and develop scalable software solutions for healthcare supply chain transactions. Collaborate with cross-functional partners to enhance the rules engine and deliver high-qualit...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$106K - $195K *

Empower product and engineering teams by delivering actionable insights that shape strategic decisions. As a Senior Decision Scientist, you'll leverage data to influence roadmaps and resource allocati...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$201K - $239K *

Grow strategic relationships with global enterprise clients, driving EHS and ESG success. Leverage consultative selling to expand accounts, collaborate cross-functionally, and ensure exceptional custo...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Engineer automated systems to enhance production efficiency and quality. Lead projects from design to implementation, optimizing processes through data analysis and collaboration with cross-functional...

2 weeks ago

  •   Less than 5 years exp.  •   Food & Beverages

$110K - $130K *

Drive innovation by developing scalable data pipelines and analytics solutions. Collaborate with teams to translate complex business problems into actionable insights across diverse domains, ensuring...

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$160K - $208K *

Transform our technology infrastructure by enhancing automation, troubleshooting issues, and fostering collaboration. Bring your expertise to support a scalable infrastructure platform that manages di...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$94K - $266K *

Transform partnerships into strategic growth by developing joint solutions, driving co-marketing efforts, and enhancing executive relationships to create lasting value in a dynamic ecosystem...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Business Services

$195K - $325K *

Join a team that's shaping the future of AI in healthcare by leading multi-year strategies, resolving complex technical challenges, and influencing executive decisions across the organization to ensur...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $125K *

Join our dynamic finance team as you drive margin and profitability through detailed analysis and strategic insights. Collaborate with senior leadership to transform data into actionable initiatives t...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$89K - $134K *

Grow your career with a dynamic role focused on private debt and equity operations. Leverage your expertise in asset lifecycle servicing while guiding junior team members and driving process improveme...

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$125K - $150K *

Take ownership of a fully distributed engineering team, driving delivery, quality, and growth while fostering a culture of communication and continuous improvement. Collaborate with cross-functional p...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $150K *

Lead a distributed engineering team to deliver high-quality software solutions. Foster a culture of ownership and continuous improvement while collaborating with cross-functional partners to drive bus...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$137K - $182K *

Architect and drive AI-powered applications for drug development, focusing on protocol generation and clinical trials. Lead technical direction, mentor engineers, and ensure compliance while fostering...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$101K - $135K *

Join a team that's shaping the future of healthcare technology by designing and enhancing our build and delivery infrastructure. Collaborate with architects and developers to implement best practices...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Innovate and implement robust disaster recovery solutions for enterprise DevOps, ensuring critical infrastructure recoverability. Oversee Jenkins, Bitbucket, and JFrog Artifactory environments while e...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Accelerate growth by building a new region from scratch, driving sales, and establishing customer success stories for a groundbreaking FinOps solution. Own the full sales cycle, focusing on net-new lo...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$77K - $202K *

Lead the charge in implementing CGI OpenGrid solutions, analyzing client needs, and guiding junior team members while enhancing operational efficiency through innovative business software solutions...

4 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$110K - $130K *

Optimize complex mechanical and electrical systems for data centers, ensuring high availability and reliability. Lead design, engineering, and project management activities while collaborating with mu...

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Drive budget management and project support for public health initiatives, ensuring accurate tracking, analysis, and reporting. Collaborate with leadership to enhance operational efficiency in a dynam...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$135K - $160K *

Join a team of expert engineers to innovate a Kubernetes resource management platform, enhancing DevOps productivity and addressing complex engineering problems in a dynamic environment...

United StatesRemote

Reposted 1 month ago

  •   Less than 5 years exp.  •   Information Technology

$240K - $330K *

Transform autonomous driving evaluation by leading initiatives that bridge model performance and real-world outcomes. Collaborate with cross-functional teams to develop metrics and tools that enhance...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Transportation

$108K - $149K *

Drive revenue operations excellence by enhancing MSSP processes and systems. Collaborate with cross-functional teams to operationalize strategies, streamline workflows, and support partner lifecycle m...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$146K - $269K *

Shape the future of enterprise software by leading multiple engineering teams, driving application development, and implementing best practices. Collaborate cross-functionally to enhance quality and s...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$88K - $98K *

Join a team that's shaping the future of paid social strategy for top consumer brands. Drive growth through innovative, data-driven campaigns on platforms like Meta, TikTok, and YouTube, while mentori...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.