Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$120K - $140K *
Empower your career by driving product marketing success through strategic commercialization, effective messaging, and cross-functional collaboration. Lead initiatives that translate complex data solu...
Yesterday
Senior Software Engineer - Front End (Library of Congress)
$100K - $135K *
Shape the future of digital services by developing user-centric applications and enhancing software engineering practices. Collaborate with cross-functional teams to deliver impactful solutions for fe...
2 days ago
Insurance Industry & Function AI Decision Science Consultant
$70K - $205K *
Drive innovative AI solutions in the Insurance sector by leveraging advanced analytics and machine learning. Collaborate with diverse teams to enhance decision-making processes and deliver impactful r...
1 week ago
$112K - $131K *
Elevate your career by leading complex financial analyses and strategic initiatives. As a senior contributor, you'll drive enhancements in reporting, support business decisions, and mentor team member...
3 weeks ago
$97K - $126K *
Transform marketing strategies by connecting buyer needs with sales execution. Lead integrated campaigns, enhance customer engagement, and drive growth through innovative go-to-market planning and col...
3 weeks ago
Commercial Real Estate Underwriting Analyst
$78K - $110K *
Contribute to high-quality pre and post-closing services in real estate underwriting. Collaborate with teams to analyze market data, assist in credit presentations, and ensure compliance with loan ter...
4 days ago
Senior Staff Machine Learning Engineer - US
$150K - $180K *
Champion innovative AI platform architecture and drive enterprise-level integration of machine learning, ensuring security, accuracy, and reliability across systems while mentoring teams to elevate te...
Reposted 1 week ago
Staff Software Engineer - Backend
$125K - $150K *
Champion the development of scalable, cloud-native applications, enhancing data pipelines and integrations. Collaborate with teams to transform raw data into actionable insights, driving improvements...
3 weeks ago
$100K - $120K *
Optimize integration processes by bridging technical gaps between systems. Collaborate with campus IT to ensure seamless data flows, troubleshoot issues, and enhance integration reliability for succes...
5 days ago
$125K - $150K *
Grow your career by owning enterprise sales processes, building relationships, and closing deals in home décor, beauty/wellness, and online retail. Drive significant revenue growth by leveraging consu...
Reposted 4 days ago
Digital and Automation Project Engineer
$82K - $114K *
Join a team that's driving innovation in digital and automation projects, ensuring compliance and standardization across capital initiatives in manufacturing environments. Collaborate with stakeholder...
1 week ago
$135K - $149K *
Analyze and enhance IT infrastructure through secure cloud solutions, ensuring 24x7 availability. Collaborate with teams to streamline workflows, improve system reliability, and tackle complex challen...
Yesterday
$92K - $166K *
Unlock potential by leading logistics analysis and execution for naval programs, ensuring effective support for maintenance, training, and compliance in a dynamic environment. Collaborate with diverse...
Today
Principal Consultant - Utility Prudence Expert
$200K - $240K *
Champion the future of energy by providing expert consulting on utility prudence, managing client engagements, and delivering impactful testimony on modernization and rate cases. Collaborate with team...
1 week ago
Director Software Engineering - Central Security
$180K - $220K *
Drive the development of innovative security systems using AI/ML, managing risk across identity and access management. Collaborate with cross-functional teams to enhance security while maintaining ope...
1 week ago
Security & Infrastructure Engineer
$100K - $120K *
Drive security excellence by managing identity access, external testing, and compliance processes. Collaborate with teams to enhance AWS security and develop scalable policies, ensuring robust protect...
3 weeks ago
$110K - $130K *
Unlock your potential as you collaborate with cross-functional teams to drive innovative thermal solutions for power products, utilizing advanced simulations and engineering expertise to meet customer...
2 weeks ago
Product Manager II, Financial Data - Screening & Search
$128K - $160K *
Manage the integration and presentation of financial data within a leading market intelligence platform. Collaborate with cross-functional teams to enhance search and agentic capabilities, ensuring da...
Reposted today
Senior Software Engineer, DevOps
$119K - $167K *
Lead the charge in evolving our cloud infrastructure and CI/CD systems. As a Senior DevOps Engineer, you'll enhance security, reliability, and operational efficiency while mentoring a team and ensurin...
Reposted 5 days ago
$80K - $95K *
Empower client success by leading integrated marketing campaigns, managing key accounts, and driving strategic growth. Collaborate with cross-functional teams to deliver impactful solutions while ment...
1 week ago
Associate - Financial Planning & Analysis (FP&A)
$80K - $95K *
Empower your career by driving financial insights and analytics. Collaborate across teams to transform data into strategic decisions, enhancing growth and efficiency in a dynamic environment. Join us...
1 week ago
Enterprise Account Executive, Acquisition | Central | Remote
$260K - $300K *
Advance your career by driving new business growth through consultative sales. Leverage your technical expertise to engage customers, manage sales processes, and foster strong relationships, ensuring...
Today
$110K - $115K *
Innovate testing strategies and enhance software quality through automated and manual verification. Collaborate across teams to ensure compliance and optimize processes while leveraging AWS and full-s...
4 weeks ago
$80K - $95K *
Drive enterprise IT infrastructure and security initiatives, optimizing cloud and networking environments while mentoring support staff and leading technology upgrades to enhance organizational perfor...
3 weeks ago
Sr. Product Manager, AI & Data
$130K - $155K *
Shape the future of data and AI solutions by driving product success, collaborating with cross-functional teams to align business goals with innovative platforms and ensuring continuous improvement th...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.