Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Sales Manager - Australia/New Zealand Market
$100K - $120K *
Accelerate sales growth by leading strategies and initiatives across the ANZ market. Collaborate with a multidisciplinary team to drive customer engagement, develop market strategies, and achieve reve...
Reposted 5 days ago
Customer Success Manager (AI Success Architect)
$116K - $148K *
Transform enterprise operations by guiding customers in AI adoption and maximizing Asana's capabilities. Own post-sales relationships, ensuring measurable outcomes and strategic success across a portf...
Today
Technical Product Owner – Data Products
$110K - $130K *
Join a dynamic team to bridge product strategy and engineering delivery, transforming data into actionable insights for innovative financial solutions. Collaborate with cross-functional teams to drive...
Reposted 1 week ago
$95K - $115K *
Lead the charge in advanced financial analysis and strategic sourcing initiatives, collaborating with cross-functional teams to drive insights and influence decision-making across multiple divisions a...
1 week ago
Director of Provider Analytics
$138K - $201K *
Transform provider analytics by leading data-driven insights for contracting, performance, and network strategy. Collaborate with cross-functional teams to enhance network adequacy and drive strategic...
4 weeks ago
Director Continuous Improvement
$120K - $150K *
Champion continuous improvement initiatives by optimizing processes and products across the organization. Lead cross-functional teams to enhance operational efficiency, quality, and customer experienc...
3 weeks ago
$131K - $209K *
Engage with teams to deliver comprehensive AI enablement programs, designing tailored learning paths and fostering a culture of proficiency across all departments. Collaborate closely with HR to integ...
Reposted today
Senior/Staff Attack Engineer, Rapid Response
$230K - $275K *
Lead the charge in vulnerability research and exploitation techniques, transforming real-world threats into automated solutions. Collaborate with teams to enhance security measures and validate defens...
3 weeks ago
Full-Stack Engineer - AI-Native Solutions
$98K - $163K *
Shape the future of enterprise software by building secure, scalable applications. Collaborate with cross-functional teams to integrate AI capabilities and deliver innovative solutions that meet busin...
Today
$85K - $125K *
Contribute to acquiring and managing data partnerships, collaborating with product teams to prioritize and improve dataset quality, while leveraging AI to enhance data processes and achieve business o...
Reposted 3 weeks ago
Lead Infrastructure Engineer - Hybrid Cloud & Automation Solutions
$130K - $155K *
Optimize and implement scalable, secure infrastructure solutions across Windows, Citrix, AWS, and Azure. Drive automation and collaborate with teams to design zero-trust architectures, enhancing infra...
4 weeks ago
Engineering Manager - Servicing & Fulfillment
$166K - $193K *
Lead and mentor a team of engineers while overseeing technical excellence and driving AI innovation in operational systems. Collaborate cross-functionally to deliver impactful features for post-purcha...
Reposted today
Sales Engineer - Laser Welding Systems
$80K - $95K *
Transform your career by delivering innovative laser solutions to clients. Engage with customers, drive sales growth, and enhance manufacturing processes in a dynamic environment focused on cutting-ed...
5 days ago
$110K - $130K *
Transform your career by building and scaling innovative growth strategies that empower Sales teams to engage effectively with customers, leveraging data, AI, and automation for measurable impact...
4 days ago
$110K - $130K *
Elevate your career by implementing and supporting AWS cloud solutions in a dynamic environment. Collaborate with experts to optimize performance and ensure secure, scalable infrastructure for federal...
1 week ago
$90K - $110K *
Transform customer experiences by driving technical excellence in post-sale support. Collaborate with teams to ensure seamless handoffs, empower account managers, and resolve escalations, all while en...
4 weeks ago
Director, Technical Products and Operations
$200K - $235K *
Drive product excellence by owning the lifecycle and security of high-performance client SaaS platforms hosted on AWS. Lead a dedicated team to optimize operations, ensure compliance, and deliver seam...
Reposted 2 weeks ago
Sr Paid Search Strategist (Enterprise)
$75K - $90K *
Transform your career by leading strategic SEM campaigns that enhance online visibility and drive conversions. Collaborate with innovative clients, analyze data, and optimize performance to exceed goa...
3 weeks ago
Senior Copywriter, Performance Marketing
$127K - $223K *
Transform the way we communicate life insurance through compelling copy that captures attention and drives action. Collaborate with teams to create impactful Direct Mail and social media content that...
Reposted today
$119K - $149K *
Lead full-cycle recruiting for technical and analytical roles, partnering with teams to define success and build diverse talent pipelines. Utilize creative sourcing and data-driven insights to enhance...
6 days ago
$80K - $95K *
Elevate your career by owning complex sales cycles in automation solutions. Drive business growth through executive relationships, multi-stakeholder pursuits, and strategic decision-making across dive...
Reposted today
Solutions Engineer | East Coast | Remote
$182K - $226K *
Innovate with a dynamic team to solve customer challenges and drive growth. Leverage your technical expertise in pre-sales to enhance customer engagement and deliver impactful solutions in a fast-pace...
4 days ago
$110K - $130K *
Join a team that empowers customers to achieve their business goals through strategic guidance and hands-on support, enhancing their experience with our DevSecOps platform and driving long-term succes...
2 weeks ago
Principal Software Engineer, Workload Orchestration (Distributed Compute))
$165K - $215K *
Architect innovative solutions to complex technical challenges, driving platform direction and enabling deep specialists. You'll tackle high-leverage problems that define our future capabilities and e...
1 week ago
$134K - $157K *
Empower a creative team to bring innovative design concepts to life while mentoring junior talent and collaborating with clients. Lead presentations and manage multiple projects, ensuring strategic in...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.