Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$120K - $150K *
Unlock potential by driving AI deployment strategies with clients, translating business needs into actionable use cases, and ensuring successful model adoption. Collaborate closely with engineers and...
1 week ago
$95K - $115K *
Unlock potential by leading a team of Business Analysts to drive strategic initiatives, enhance stakeholder engagement, and operationalize an embedded BA model, fostering growth and transformation wit...
1 week ago
$80K - $95K *
Unlock potential by driving outbound sales strategies, managing a robust pipeline, and converting prospects into clients. Collaborate with healthcare companies to identify opportunities and achieve qu...
2 weeks ago
$80K - $95K *
Join a team that's shaping the future of AI solutions by deploying and integrating cutting-edge technologies. Collaborate with customers and engineers to enhance system performance and drive innovatio...
2 weeks ago
Director of Applied AI Engineering
$207K - $290K *
Elevate your career by leading a dynamic Applied AI team, transforming innovative AI solutions into production-ready systems within a regulated financial environment, while collaborating across depart...
2 weeks ago
$120K - $175K *
Pioneer insights at the intersection of Sales, Marketing, and CS by owning and enhancing analytical infrastructure to generate decision-ready insights that drive growth in a dynamic, fast-paced enviro...
Reposted 1 week ago
$120K - $145K *
Transform the engineering landscape by owning architecture, deployment, and incident management. Collaborate with teams to prioritize features, enhance payment systems, and integrate AI, all while ens...
Today
$125K - $150K *
Drive enterprise growth by strategically engaging high-value accounts, orchestrating complex sales processes, and leveraging AI capabilities to enhance compliance workflows. Build executive relationsh...
5 days ago
Senior Director, Commercial Analytics & Decision Science
$219K - $285K *
Shape and lead a centralized commercial analytics function, transforming complex data into actionable insights. Drive performance measurement, growth identification, and strategic decision-making acro...
1 week ago
$125K - $150K *
Empower growth by owning strategic partnerships, driving go-to-market plans, and ensuring compliance. Collaborate across teams to enhance revenue and strengthen relationships, while managing budgets a...
Yesterday
EverCommerce - Senior Business Systems Analyst - HRIS
$110K - $140K *
Lead system enhancements and process improvements for HRIS, focusing on optimizing functionalities and automating workflows to support HR initiatives. Collaborate with cross-functional teams to align...
Reposted 2 weeks ago
$95K - $115K *
Optimize customer engagement by architecting automated workflows and data-driven insights. Collaborate with teams to enhance communication strategies and drive measurable outcomes, ensuring a seamless...
4 days ago
$140K - $175K *
Develop innovative software solutions that enhance access to mental and physical health services. Collaborate with cross-functional teams to deliver reliable applications, ensuring quality and perform...
Today
SAP Business AI Lead Architect
$160K - $229K *
Lead the design and development of AI-driven solutions within SAP S/4HANA, integrating advanced AI technologies to drive business transformation and innovation across enterprise environments. Mentor t...
1 week ago
Radar Signal Processing Engineer
$95K - $115K *
Transform the future of radar technology by developing advanced signal processing algorithms within a collaborative R&D environment, enhancing radar systems through innovative research and multidiscip...
Reposted 3 weeks ago
Aviation Sustainability and Policy Specialist
$80K - $95K *
Unlock potential by leading ESG and sustainability strategies for business aviation. Collaborate with industry partners and Fortune 500 clients to navigate regulations, develop innovative solutions, a...
1 week ago
Senior Solutions Engineer, Acquisition | Central | Remote
$204K - $254K *
Lead technical engagements with customers, driving product success through demos, presentations, and collaboration with sales. Contribute to a high-growth team focused on innovative solutions and cust...
4 days ago
$137K - $231K *
Empower your career by shaping design systems that enhance user experience. Collaborate with teams to build high-quality, interactive UI across platforms, ensuring accessibility and performance while...
2 weeks ago
Staff Site Reliability Engineer
$156K - $275K *
Lead the charge in shaping the technical strategy for reliability and infrastructure. Drive initiatives across teams, design scalable systems, and enhance operational excellence while mentoring engine...
Reposted today
Lead Analyst - Independent Assessment
$98K - $115K *
Lead independent assessments to evaluate and enhance the Bank's risk management practices, ensuring compliance with evolving regulatory standards while guiding a team of analysts in a dynamic environm...
5 days ago
$130K - $200K *
Drive impactful design and development of front-end features, owning the code from concept to production. Collaborate with teams to establish design systems and set direction for user-centric products...
6 days ago
$120K - $140K *
Shape the future of federal financial operations by driving user adoption and change management for a new tool. Collaborate with stakeholders to enhance user experience, streamline processes, and ensu...
2 weeks ago
Staff Software Engineer, Audiences
$150K - $180K *
Lead the charge in developing scalable audience solutions by integrating predictive models and data workflows. Collaborate with cross-functional teams to enhance audience activation and ensure reliabl...
1 week ago
Solution Architect- Digital & AI Products
$73K - $218K *
Lead the charge in designing innovative digital solutions that enhance operational performance and customer experience. Collaborate across teams to translate complex business challenges into scalable...
4 days ago
National Accounts Lead Director, Clinical Program Consultant (CPC)
$100K - $231K *
Transform healthcare outcomes by leading a team of Clinical Program Consultants to analyze data, optimize clinical programs, and drive strategic initiatives that enhance customer health and reduce cos...
Reposted 3 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.