Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Remote Sensing / Signal Processing Software Engineer
$135K - $145K *
Lead the development of advanced geospatial systems by integrating software, algorithms, and data processing for remote sensing and signal processing applications, ensuring seamless interaction across...
2 weeks ago
$218K - $256K *
Lead the charge in shaping IT strategy and operations for a remote-first SaaS company. Drive service delivery, enhance employee technology experiences, and build a high-performing IT organization whil...
2 weeks ago
HVAC Engineering Consultant 2 - Nuclear
$118K - $180K *
Grow your career with a dynamic team focused on designing innovative HVAC systems. Engage in challenging projects, collaborate with experts, and contribute to the development of cutting-edge solutions...
1 week ago
Experienced Electrical Engineering Consultant
$100K - $152K *
Elevate your career by leading consulting engagements in utility-scale power generation, focusing on renewable energy and battery storage. Collaborate with clients and stakeholders to deliver innovati...
3 weeks ago
Platform Engineer (ServiceNow)
$110K - $130K *
Pioneer the administration and development of core business systems, focusing on ServiceNow. Collaborate with cross-functional teams to create scalable solutions that enhance operations, service, and...
Reposted 1 week ago
Snr Platform Engineer - Salesforce & Integrations
$100K - $115K *
Engineer innovative Salesforce solutions and integrations, enhancing business applications and operational efficiency. Collaborate with cross-functional teams to deliver secure, scalable technology th...
Today
$255K - $383K *
Transform enterprise relationships by leading strategic sales initiatives, managing complex cycles, and nurturing partnerships to drive significant revenue growth in a high-impact territory...
6 days ago
Senior/Staff Full Stack Software Engineer
$180K - $240K *
Unlock innovative solutions as you build full-stack applications for federal partners, focusing on user experience, security, and seamless integrations. Collaborate with engineers and product teams to...
4 days ago
Salesforce Technical Architect
$135K - $160K *
Champion innovative Salesforce Field Service solutions, leading implementations and integrations while mentoring teams and advising clients on optimization and transformation strategies for enhanced o...
6 days ago
$110K - $130K *
Join a team that's dedicated to driving client success and growth by managing a substantial book of business. Leverage your expertise in account management to foster relationships and influence produc...
2 weeks ago
Workforce Intelligence Consultant
$145K - $160K *
Empower healthcare leaders by delivering actionable insights through advanced analytics. Collaborate with executives to address strategic workforce challenges, utilizing AI-driven data solutions to en...
4 days ago
AI Clinical Solutions Engineer, Azurion Eye (Asheville, NC or Nashville, TN)
$140K - $223K *
Unlock potential by bridging clinical practice with AI innovation. Collaborate with clinicians and engineers to enhance workflows and patient care through AI-driven imaging solutions in a hospital set...
1 week ago
Senior Product Manager, AI Evaluation & Quality| Level 18| US: Remote
$150K - $159K *
Analyze and build evaluation frameworks for AI agents, ensuring quality and performance meet client and business standards. Collaborate with cross-functional teams to establish testing methodologies a...
6 days ago
$104K - $130K *
Contribute to ICT design and project management for mission-critical data centers and smart buildings. Collaborate with technical teams, manage project scopes, and utilize advanced tools to enhance ef...
Yesterday
$110K - $130K *
Shape the future of secure software development by integrating security practices into engineering workflows, building automation tools, and conducting penetration tests to identify vulnerabilities an...
2 weeks ago
$76K - $115K *
Optimize billing operations and enhance contract management by collaborating cross-functionally. Drive accuracy in invoicing, support month-end close, and streamline processes to improve efficiency an...
4 days ago
Lead Actuarial Predictive Modeler
$110K - $130K *
Optimize predictive modeling initiatives by designing and implementing advanced actuarial pricing models. Collaborate with cross-functional teams to ensure compliance and drive strategic pricing solut...
1 week ago
Director of Engineering, Webapp & AI Attack
$290K - $340K *
Lead and inspire engineering teams to develop cutting-edge web and AI security solutions. Drive strategy, execution, and organizational health while fostering a culture of innovation and accountabilit...
1 week ago
Lead Analyst – Independent Assessment
$98K - $115K *
Lead independent assessments to evaluate bank practices against regulatory standards, ensuring quality and compliance. Collaborate with stakeholders to enhance risk management frameworks and contribut...
4 days ago
$72K - $104K *
Lead the charge in enhancing customer care quality through effective monitoring, collaboration, and continuous improvement initiatives. Drive actionable insights and training to elevate service standa...
2 days ago
Senior Architect - Data Platforms & Architecture
$145K - $175K *
Lead the charge in architecting scalable Azure solutions across multi-team programs, aligning client goals with innovative designs. Mentor teams, drive modernization efforts, and ensure high-quality d...
3 days ago
Senior Software Engineer, AI Platform
$138K - $165K *
Transform AI capabilities by building robust SDKs and infrastructure. Collaborate with product teams to enhance agent workflows, ensuring reliability and performance while driving innovation in AI exp...
Today
Staff Engineer - QA Automation
$110K - $130K *
Shape the future of quality assurance by leading automated testing initiatives for cloud-based ERP systems, ensuring seamless integration and performance across various business processes and upgrades...
3 weeks ago
$115K *
Join a team that's dedicated to driving sales success through lead generation and client education. This role involves delivering impactful product demonstrations and collaborating with sales teams to...
Today
Director, Internal AI Operations
$269K - $370K *
Join a team that's transforming AI into a measurable business capability. Lead strategic initiatives, optimize operations, and collaborate across functions to enhance AI adoption and efficiency while...
4 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.