Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$100K - $130K *
Champion the delivery of data and AI initiatives by engaging stakeholders and technical teams. Drive strategy and execution while ensuring alignment between business objectives and scalable technology...
Reposted 1 week ago
Senior / Lead Site Reliability Engineer
$112K - $154K *
Advance your career as a Senior Site Reliability Engineer, focusing on automation, reliability, and performance. Collaborate with teams to enhance application performance and operational efficiency wh...
Today
$120K - $145K *
Join a dynamic team to drive technical success and adoption across enterprise accounts. Leverage your expertise in project management and technical execution to enhance deployment health and fuel acco...
Reposted today
Associate Director AI Product Engineer - Financial Institution Operations & Technology
$180K - $250K *
Drive the evaluation of AI products in banking, ensuring accuracy and reliability through automated testing and performance measurement. Collaborate with experts to enhance product quality from develo...
Yesterday
$82K - $131K *
Elevate customer engagement by driving successful project delivery, fostering collaboration across teams, and ensuring satisfaction through proactive communication and effective management of complex...
Reposted 3 weeks ago
$150K - $180K *
Lead the transformation of innovative technologies into market-ready products, collaborating with cross-functional teams to identify customer needs, prototype solutions, and drive commercialization fr...
2 weeks ago
$120K - $160K *
Analyze complex data and drive solutions as a Business Analyst in the public sector. Leverage your expertise in pension systems to identify issues and enhance processes, ensuring effective communicati...
Reposted 1 week ago
Principal Business Intelligence Lead, System Performance
$200K - $275K *
Elevate data strategy and reporting for the System Performance Organization, transforming complex robotics data into compelling narratives for executive stakeholders while fostering team growth and al...
Reposted 1 week ago
Senior Director, Dedicated Infrastructure & Platforms
$279K - $349K *
Drive the strategy and execution of dedicated infrastructure engineering, leading a high-performing team to enhance enterprise SaaS offerings, ensure compliance, and deliver exceptional customer exper...
1 week ago
Chief Technology Officer - Databricks Data & AI Platform
$210K - $250K *
Champion transformative data strategies and lead technical pursuits in AI and data migration. Drive client success and practice growth while enhancing market presence through strategic partnerships an...
2 weeks ago
Senior Associate, Compliance Model Governance
$148K - $175K *
Unlock potential by leading quantitative testing and monitoring for AI models in compliance, ensuring data quality and regulatory adherence while collaborating across teams to enhance financial crime...
Today
Enterprise Sales, Commercial Practice
$140K - $160K *
Drive new business development and revenue growth by leveraging professional networks and sales expertise to secure major client engagements and enhance executive relationships within Fortune 500 comp...
Reposted 2 weeks ago
$131K - $205K *
Shape the future of electric power projects by providing expert development support, technical evaluations, and engineering design reviews. Collaborate with clients to optimize project outcomes while...
2 weeks ago
$110K - $130K *
Lead a dynamic SOC team as a Senior Cybersecurity Analyst, enhancing threat detection and incident response through AI and machine learning. Drive security improvements and mentor team members while s...
2 weeks ago
Technical Recruiter - Controls and Robotics Engineering
$80K - $95K *
Join a team that's dedicated to sourcing top technical talent for innovative automation solutions. Leverage your recruiting expertise to engage candidates and support our mission of enhancing efficien...
Yesterday
Lifecycle Acquisition Analyst, Mid
$78K - $90K *
Unlock potential by providing expert lifecycle acquisition support for NGA programs, developing key documentation, and ensuring timely procurement actions through collaboration with technical and fina...
6 days ago
Senior Backend Engineer (Integrations & Platform)
$150K - $185K *
Unlock potential by designing and maintaining scalable backend systems for complex data integrations. Collaborate with partners to enhance operational efficiency and reliability, ensuring seamless dat...
1 week ago
Senior Workplace Engineering Lead
$87K - $230K *
Champion modern workplace transformations by leading technical investigations, collaborating with cross-functional teams, and enhancing employee technology experiences through scalable solutions...
1 week ago
$63K - $129K *
Join a dynamic team to support lifecycle management for Military Sealift Command ships, focusing on long-term maintenance and operational planning while ensuring compliance with engineering standards...
1 week ago
$83K - $124K *
Unlock potential by leading the design and implementation of CI/CD pipelines, enhancing software delivery and operational stability for enterprise applications while collaborating with cross-functiona...
1 week ago
$78K - $131K *
Inspire growth by partnering with leaders to design impactful learning experiences that enhance performance across teams. Drive initiatives that empower employees to achieve their goals and improve pr...
1 week ago
Staff Software Engineer - Performance Advisor
$220K - $240K *
Shape the future of loyalty by leading the technical execution and innovation of AI-powered features in a rapidly evolving product landscape, driving cross-functional initiatives with a focus on archi...
Reposted 3 weeks ago
Lead Service Integration Engineer
$120K - $145K *
Transform fragmented IT landscapes as you lead complex service integration projects, improving data flow and visibility across hybrid cloud and on-premise environments. Guide cross-functional teams an...
Reposted today
$91K - $161K *
Join a team that's shaping the future of cloud IT by designing secure, scalable systems. Collaborate across the organization to implement innovative solutions and drive operational excellence, leverag...
Reposted today
Enterprise Account Executive, Healthcare
$272K - $374K *
Develop strategic relationships with key healthcare accounts, driving innovation and sales growth. Leverage your expertise in big data and cloud technologies to exceed targets and deliver exceptional...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.