Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Manager, Tagging and Analytics
$113K - $130K *
Join a team that's dedicated to ensuring data quality and governance in retail analytics. You'll lead tagging initiatives, collaborate with internal and external partners, and empower teams with best...
2 weeks ago
Senior Product Marketing Manager, AI
$120K - $145K *
Engage with cross-functional teams to drive AI security product marketing initiatives, focusing on buyer insights, competitive analysis, and effective sales enablement. Collaborate on launches and con...
Reposted today
Human Solutions Senior Consultant
$90K - $125K *
Pioneer client solutions by leading project management, mentoring teams, and collaborating with stakeholders. Drive analysis and presentations while addressing client needs and ensuring deliverables m...
1 week ago
Human Solutions Senior Consultant
$90K - $125K *
Champion innovative solutions as you lead project management and client engagement, driving success through collaboration and mentorship while managing diverse health consulting projects and stakehold...
1 week ago
Solution Architect, Forward Deployed Architecture (AI Capability Center)
$145K - $170K *
Design innovative AI solutions on Microsoft Azure, bridging business needs and engineering execution. Own the architecture, ensure security, and lead the build process while adapting to evolving proje...
2 weeks ago
Software Engineer, Java/Python & AI
$150K - $180K *
Lead the development of enterprise-grade applications using Java, Python, and AI technologies. Collaborate with cross-functional teams to design and implement robust software solutions in a dynamic, A...
Today
$150K *
Drive enterprise sales in HR tech by building a pipeline and closing complex deals. Collaborate with teams to establish executive relationships and create account strategies that convert prospects int...
Today
Senior Analyst, Marketing Strategy & Operations
$111K - $167K *
Drive impactful marketing strategies by leveraging data analysis and AI tools. Collaborate cross-functionally to enhance funnel performance, ROI modeling, and operational efficiency, ensuring alignmen...
4 days ago
$105K - $141K *
Lead the charge in developing innovative pricing strategies that drive long-term monetization across cloud and AI products. Collaborate cross-functionally to create scalable frameworks and influence s...
3 weeks ago
21GRAMS- Senior Technology Lead
$119K - $140K *
Shape the future of technology in healthcare by leading development efforts, leveraging AI tools, and ensuring high-quality digital deliverables across multiple platforms. Collaborate with creative te...
Reposted 2 weeks ago
Business Analyst, Product Creation Technology
$80K - $90K *
Transform business needs into actionable requirements by bridging technical solutions and operational workflows. Collaborate across teams to enhance product creation technology systems, ensuring seaml...
Reposted 3 days ago
$93K - $150K *
Optimize infrastructure and CI/CD pipelines to empower engineering teams in delivering AI-powered products efficiently. Collaborate closely with product and data engineers, leading projects from incep...
1 week ago
$140K - $160K *
Drive high-volume technical recruitment efforts, focusing on specialized roles like Data Scientists and AI Engineers. Collaborate with hiring managers to build strong candidate pipelines and ensure an...
5 days ago
Principal Full-Stack Data Scientist - Foundational Models
$200K - $237K *
Join a dynamic team to design and deploy cutting-edge machine learning models that enhance personalization and recommendations, driving impactful solutions across diverse datasets and collaborating wi...
Today
Procurement Operations Analyst
$115K - $150K *
Elevate procurement operations by managing vendor coordination, documentation, and process consistency. This role focuses on execution and queue management, ensuring timely and organized procurement s...
1 week ago
Product Lead, Predictive Platform
$188K - $255K *
Join a team that's empowering predictive modeling excellence. Lead and scale a product management pod while owning the core predictive foundation and driving transformative modeling initiatives in a h...
Reposted today
Senior Expert Engineer (Industrial Services)
$149K - $205K *
Transform utility systems across a factory network by providing technical leadership, ensuring safety, reliability, and sustainability while supporting capital projects and improving asset performance...
3 weeks ago
Software Engineer (Technical Leadership) - Central Growth
$175K - $210K *
Innovate and lead the technical vision for large-scale product systems, driving cross-functional initiatives and engineering excellence while mentoring teams to enhance growth and impact across multip...
2 weeks ago
Advanced Information Technologist – Mid Level Cloud Engineer
$119K - $161K *
Shape your career as a Cloud Engineer by optimizing deployment processes, managing vendor integrations, and ensuring efficient cloud operations across various environments. Drive success through innov...
Reposted 3 days ago
$120K - $145K *
Transform the interaction of mobile robots with their environments by developing cutting-edge learning-based manipulation systems that enhance reliability and safety in dynamic settings, impacting rea...
Reposted today
Engineering Manager, Integrations
$187K - $234K *
Empower the Integrations team to scale impact by leading third-party integrations, creating reusable capabilities, and fostering a collaborative culture that drives effective delivery and continuous i...
6 days ago
$135K - $160K *
Lead the charge in designing cutting-edge infrastructure for large-scale AI deployments. Collaborate with multidisciplinary teams to ensure seamless execution from concept to construction, maintaining...
2 weeks ago
Configuration Management (CfM) Analyst
$96K - $148K *
Unlock potential by managing configuration data integrity and processes. Collaborate with teams to design workflows in ServiceNow, ensuring accurate configuration management while driving continuous i...
1 week ago
Senior Director, Software Engineering
$145K - $190K *
Lead the charge in designing and optimizing scalable data pipelines using Azure, PySpark, and Airflow. Collaborate with teams to ensure data quality and performance while mentoring engineers and drivi...
2 weeks ago
$115K - $130K *
Analyze market trends and performance metrics to drive actionable insights across marketing, sales, and revenue operations. Collaborate with cross-functional teams to optimize strategies and enhance g...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.