Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$120K - $140K *
Innovate cloud solutions by designing and automating infrastructure in Cloud.gov and Azure. Collaborate with teams to enhance performance and security, driving impactful results for clients while shap...
Reposted 6 days ago
$125K - $150K *
Innovate AI-driven business applications by designing Python services and APIs that enhance data processing capabilities in both cloud and on-premises settings, ensuring robust performance and seamles...
Reposted 3 days ago
$86K - $107K *
Lead advanced analytics projects that drive strategic decisions, optimize sales productivity, and enhance operational efficiency. Collaborate with executives to deliver data-driven insights and implem...
3 days ago
Senior ITCR / Requirements Analyst
$79K - $122K *
Shape the future of IT capabilities by leading requirements analysis and advisory support for a Department of War agency. Collaborate with stakeholders to deliver data-driven insights and enhance ente...
1 week ago
Senior Staff Applied Scientist, Science Platform
$232K - $325K *
Join a dynamic team to lead the development of advanced analytics tools, leveraging your expertise in statistics and machine learning to drive impactful decision-making across the organization...
Yesterday
$125K - $150K *
Transform business workflows by developing and maintaining applications that enhance productivity and information sharing across teams. Collaborate with IT and business units to deliver innovative sol...
Reposted yesterday
Integrations Engineer, AI Services
$110K - $130K *
Unlock potential by designing and delivering scalable AI-powered integrations for nonprofits. Collaborate closely with clients to understand their needs, build solutions, and productize offerings that...
Yesterday
Senior Business Insights Analyst
$110K - $131K *
Transform complex data into actionable insights, partnering with leaders to enhance strategic decision-making and drive organizational performance through advanced analytics and reporting frameworks...
6 days ago
Lead AI and Data Solution Engineer
$200K - $215K *
Drive innovation in data engineering and AI solutions, leading the design and deployment of scalable systems. Collaborate with cross-functional teams to enhance business value through advanced technol...
3 weeks ago
$120K - $145K *
Champion data excellence by designing and optimizing scalable data platforms. Collaborate with cross-functional teams to enhance performance and drive innovation in data processing, ensuring alignment...
Today
Senior Digital Paid Ad Manager
$149K - $185K *
Lead the strategy and execution of paid digital advertising programs, optimizing campaigns across multiple channels to drive measurable pipeline and revenue impact. Collaborate with cross-functional t...
3 weeks ago
Associate Director, Analytics and Data Products
$125K - $145K *
Lead the charge in building and delivering data products that empower leadership and client engagements. This hands-on role requires strategic oversight and collaboration to ensure high-quality analyt...
1 week ago
Sr. Data Analyst, Customer Analytics (Insurance)
$84K - $120K *
Accelerate insights generation as a key member of the Customer Analytics team, transforming raw data into actionable recommendations that enhance client retention, drive growth, and refine operational...
Reposted 3 weeks ago
Senior Director, Marketing Intelligence
$245K - $288K *
Join a team that's redefining marketing intelligence by leveraging data to shape strategies, drive growth, and enhance audience understanding. Lead a high-performing team to transform insights into ac...
5 days ago
Senior Marketing Operations Analyst
$106K - $141K *
Join a team that's building an AI-ready data foundation for marketing and GTM. You'll design, govern, and analyze data models, ensuring reliable insights for strategic decision-making across the organ...
2 weeks ago
$85K - $95K *
Transform data into actionable insights by developing predictive models and automating workflows. Collaborate in a dynamic environment to enhance decision-making and operational efficiency using advan...
Reposted 1 week ago
$130K - $155K *
Unlock your potential by owning the technical design of a comprehensive data platform. Collaborate with cross-functional teams to deliver trustworthy data solutions that enhance product performance an...
6 days ago
$110K - $130K *
Elevate data engineering capabilities by designing robust ETL/ELT workflows, ensuring data quality, and implementing scalable solutions on AWS and Kubernetes. Collaborate with teams to optimize perfor...
3 weeks ago
$140K - $160K *
Design and enhance intelligent AI systems for K-12 assessment, collaborating across disciplines to create reliable, evaluative solutions that integrate seamlessly into educational frameworks and suppo...
Today
$140K - $160K *
Advance the design and implementation of a robust knowledge architecture for K-12 assessment systems, integrating AI and learning science to enhance educational outcomes through innovative, data-drive...
Today
$110K - $130K *
As an Account Executive at Forma.ai, you will drive revenue growth by identifying and closing enterprise-level deals while managing a robust pipeline of Fortune 1000 prospects. You will engage with se...
Reposted today
$110K - $120K *
Elevate pricing strategies by analyzing data, guiding deals, and enhancing profitability. Collaborate across teams to drive smarter pricing decisions and improve seller experiences, ensuring competiti...
1 week ago
Senior Director, Client Strategy
$175K - $225K *
Champion client success by leading a dynamic team to drive growth strategies, enhance client relationships, and integrate innovative solutions. Influence operational excellence while fostering a cultu...
Reposted today
Petrotechnical Data Solutions Engineer (Upstream)
$110K - $218K *
Unlock your potential by delivering data-driven solutions for upstream oil and gas operations. Collaborate with experts to enhance analytics and AI capabilities, driving informed decisions across expl...
1 week ago
Petrotechnical Data Solutions Engineer (Upstream)
$110K - $218K *
Help us advance upstream oil and gas operations by building data-driven AI solutions. Collaborate with experts to enhance decision-making through innovative data engineering and analytics, contributin...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.