Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$195K - $235K *

Drive innovation in autonomous systems by building robust platforms for AI agents, ensuring seamless execution and user-friendly interfaces while tackling complex distributed systems challenges across...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$159K - $230K *

Empower community growth by engaging stakeholders and driving strategic initiatives. Collaborate with cross-functional teams to enhance social impact and develop actionable insights for data center ma...

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Lead the charge in driving sales growth and customer engagement by managing key accounts and project strategies. Collaborate with cross-functional teams to enhance product positioning and deliver exce...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Unlock potential by managing client relationships and Meta campaigns, ensuring performance and retention. Lead strategy discussions, optimize advertising efforts, and translate data into actionable in...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $160K *

Lead the charge in managing and optimizing WEKA deployments for AI hyperscaler customers, ensuring seamless data layer operations and infrastructure tuning to meet diverse workloads while maintaining...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Collaborate to enhance enterprise observability capabilities across cloud, infrastructure, and AI-driven platforms. Lead technical initiatives, improve operational excellence, and define observability...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$84K - $126K *

Join a team that's driving growth in the cardiovascular ASC market by developing strategic partnerships and executing innovative market strategies across the U.S. Collaborate with diverse stakeholders...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Business Services

$105K - $129K *

Elevate client engagement through data-driven insights! As a Senior Analyst, you'll analyze performance metrics, enhance marketing strategies, and drive client retention, ensuring impactful decisions...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$100K - $120K *

Collaborate with cross-functional teams to ensure optimal data center operations, managing infrastructure setup, troubleshooting, and documentation while maintaining high standards for deployment and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Lead the charge in customer success by ensuring seamless integration and support for connected hardware, driving account growth through exceptional service and technical expertise...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$130K - $155K *

Transform our platform by enhancing performance and reliability as a Senior Site Reliability Engineer. Collaborate with teams to optimize Ruby on Rails applications, leverage AI for operational effici...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $120K *

Grow your career with a dynamic sales role, driving supply chain transparency for leading brands. Own the full sales cycle, engage senior stakeholders, and develop solutions that enhance customer valu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $100K *

Champion your expertise to drive and optimize innovative commerce media strategies, ensuring client satisfaction and measurable success across diverse marketing channels in a fully remote environment...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$80K - $100K *

Optimize marketing campaigns within the commerce media ecosystem, developing tailored omnichannel strategies to drive client success and satisfaction while leveraging data-driven insights for continuo...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$126K - $173K *

Drive integration strategies to enhance silicon photonic fabrication, collaborating with foundries to evolve processes from development to production while ensuring robust performance and reproducibil...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$110K - $140K *

Pioneer GxP compliance in digital quality management, ensuring software and AI products meet regulatory standards. Collaborate with stakeholders to enhance quality processes and support audits, drivin...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $115K *

Explore a strategic leadership role focused on developing omnichannel engagement strategies that connect media, analytics, and customer experiences, driving measurable outcomes for healthcare brands a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $187K *

Accelerate progress at client engagement by managing relationships, driving sales strategies, and ensuring delivery excellence. Collaborate with teams to create account plans and optimize performance...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $200K *

Partner with us to elevate customer success by delivering technical expertise and support. Your role will bridge customer interactions and product enhancements, driving satisfaction and ensuring optim...

RemoteRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Join a team that's dedicated to enhancing coding accuracy through comprehensive audits and educational support. Leverage your expertise in ICD-10, CPT, and HCPCS coding to drive compliance and improve...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$185K - $312K *

Transform the Agentic Platform as a Principal PM, leading AI agent development across teams. Shape technical direction, enhance developer experience, and ensure seamless integration for impactful cust...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$90K - $110K *

Join a team that's dedicated to enhancing software quality through innovative test automation. Collaborate with cross-functional teams to design, develop, and execute automated testing solutions that...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $110K *

Analyze and optimize workforce management strategies across multiple business lines, translating complex forecasts into actionable capacity plans and financial models while collaborating with executiv...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$185K - $344K *

Champion the evolution of field intelligence capabilities, driving strategic governance and analytics integration to enhance decision-making and execution support across the organization, ensuring ali...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Grow your career with a dynamic role that combines technical expertise and sales acumen. Engage with clients, scope security assessments, and collaborate with teams to deliver tailored solutions while...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.