Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$125K - $150K *

Drive growth at a large strategic account by delivering AI & Data solutions. Engage closely with executives, align teams, and ensure client satisfaction while leading impactful programs in Retail, CPG...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Engage in comprehensive program management for data center operations, ensuring seamless transitions from construction to live operations. Shape maintainability, drive incident improvements, and enhan...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$227K - $280K *

Lead strategic finance initiatives to empower product decisions, driving financial evaluations and business cases for new product lines. Collaborate with C-suite and product teams to optimize resource...

RemoteRemote

3 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$80K - $95K *

Lead the configuration and support of Epic applications, ensuring seamless integration and optimal performance. Collaborate with teams to enhance workflows, troubleshoot issues, and drive project succ...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$125K - $150K *

Unlock your potential as you drive Oracle EPM Cloud Planning solutions, supporting clients in their transformations. Leverage your expertise to configure, implement, and coach while enhancing project...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$105K - $130K *

Transform your career by leading automation projects that enhance manufacturing efficiency. Collaborate with cross-functional teams to implement innovative solutions while ensuring safety and complian...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Food & Beverages

$120K - $170K *

Lead the development of scalable systems, balancing individual contributions with technical guidance. Collaborate across teams to tackle complex engineering challenges in security and AI, while evolvi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Explore a dynamic role supporting electrical engineering across renewable and thermal assets. Collaborate on system protection, safety, compliance, and operational reliability while driving innovative...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Energy & Utilities

$210K - $230K *

Drive your career with a dynamic role focused on enterprise B2B sales, where you'll cultivate relationships, leverage data insights, and collaborate cross-functionally to close high-value deals in a f...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$95K *

Join a team that's driving growth by managing key Integrator accounts, developing sales strategies, and fostering relationships to exceed corporate goals in the material handling industry...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Unlock potential by driving complex sales into Fortune 2000 accounts, engaging with key stakeholders in compliance and technology. Shape the future of AI in enterprise solutions while achieving ambiti...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $169K *

Transform customer outcomes by leading a high-performing team dedicated to leveraging Samsara's solutions. Drive strategic growth while ensuring enterprise clients realize sustained value from their i...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$73K - $109K *

Elevate your career by managing mechanical engineering projects from initiation to completion, ensuring efficient and safe execution of capital projects in manufacturing environments, while providing...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Unlock potential by driving digital transformation in Life Sciences. Engage with CxOs and R&D teams to deliver innovative SaaS solutions, navigate complex sales cycles, and build lasting partnerships...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Innovate in mission planning by developing autonomous operations for satellite constellations. Collaborate with cross-functional teams to define requirements, prototype code, and optimize algorithms...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$150K - $180K *

Join a dynamic team to architect and implement cutting-edge MLOps strategies, leveraging Google Cloud's AI/ML stack. Drive innovation in model lifecycle management and collaborate with cross-functiona...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$125K - $168K *

Pioneer application modernization efforts by leading agile teams, driving technical outcomes, and enhancing developer experiences. Collaborate with clients to deliver measurable business results while...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$88K - $150K *

Shape the future of cybersecurity by driving growth in strategic accounts. Leverage your expertise to build executive relationships, navigate complex sales cycles, and expand our compliance audit and...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $90K *

Shape the future of integrated marketing strategies by owning the creative process from ideation to execution. Collaborate with teams to deliver impactful campaigns that drive performance and renewals...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Media

$155K - $410K *

Unlock your potential as you lead AWS-native application engineering initiatives, guiding teams through design, development, and modernization while shaping client relationships and driving strategic...

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$110K - $130K *

Join a dynamic team to design and optimize enterprise infrastructure, leading initiatives in network architecture, virtualization, and cloud services while ensuring reliability and security across sys...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $175K *

Empower mission success by managing COMSEC lifecycle functions, ensuring the security and integrity of communication systems through expert oversight and compliance with national standards...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Aerospace & Defense

$143K - $169K *

Drive strategic revenue forecasting and reporting for hardware, collaborating with cross-functional teams to enhance decision-making and insights. Engage with executive leadership to shape narratives...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$94K - $224K *

Shape a safer workplace by leading global industrial hygiene initiatives. Develop programs, ensure compliance, and engage stakeholders to foster a culture of health and safety while integrating innova...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Elevate client outcomes by managing complex AI and data programs. Serve as the primary contact for multi-geo teams, ensuring technical delivery aligns with business goals. Foster strong relationships...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.