Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$110K - $130K *

Contribute to customer success as a technical liaison, driving adoption of AI-driven solutions while collaborating with cross-functional teams to enhance product value and performance. Foster strong r...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$116K - $155K *

Transform enterprise applications through strategic architecture, integration, and governance. Collaborate with stakeholders to enhance business processes and ensure reliable operation of platforms wh...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Energy & Utilities

$159K - $230K *

Empower teams to drive innovative solutions in data center operations. Lead complex projects, manage schedules, and collaborate across functions to ensure seamless execution and delivery of cutting-ed...

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Champion the delivery of civil works and architectural projects, overseeing contractors and ensuring high-quality execution from site prep to completion. Leverage your expertise to manage complex site...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$70K - $126K *

Analyze program outcomes and collaborate with stakeholders to enhance results. Manage complex projects, provide insights to leadership, and educate agencies on best practices to optimize performance a...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $175K *

Engineer and optimize enterprise platforms for diverse environments, ensuring seamless deployment and support. Collaborate with clients to enhance cybersecurity, compliance, and observability solution...

RemoteRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Shape the future of enterprise sales by driving innovation and closing deals. Collaborate with key stakeholders to expand customer vision and exceed revenue targets while managing complex sales cycles...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Drive enterprise sales by closing new and existing accounts, leveraging deep product knowledge and customer relationships to exceed revenue targets and deliver innovative solutions in the big data and...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Architect robust data solutions by leveraging modern architectures and ETL processes. Collaborate with stakeholders to enhance data quality and drive impactful analytics. Lead initiatives to automate...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Drive regulatory intelligence initiatives to ensure compliance and support clinical research. Collaborate with experts to assess regulatory changes, track global guidelines, and enhance impact assessm...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$63K - $111K *

Elevate project execution by supporting engineering and construction teams in delivering complex industrial infrastructure projects through technical coordination and quality assurance activities...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$120K - $145K *

Transform your career by owning AWS cloud operations, enhancing reliability, performance, and cost efficiency. Collaborate with cross-functional teams to ensure seamless service delivery and operation...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$162K - $238K *

Design and optimize R&D operations to enhance organizational effectiveness through data-driven insights, collaboration, and governance. Partner cross-functionally to drive continuous improvement and e...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Information Technology

$159K - $196K *

Oversee comprehensive partner audit efforts, ensuring compliance with standards, addressing concerns, and collaborating on solutions. Provide guidance, implement corrective actions, and keep leadershi...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$86K - $118K *

Take ownership of hardware operations by installing, configuring, and troubleshooting technical equipment. Collaborate with teams to maintain infrastructure and ensure optimal performance in a dynamic...

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Empower customer success by designing impactful journeys that drive retention and revenue. Lead cross-functional teams to create and optimize service blueprints, ensuring seamless customer experiences...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$94K - $293K *

Transform talent strategies by integrating AI and data-driven insights to enhance workforce agility and productivity. Lead end-to-end Talent Transformation initiatives, redefining processes and operat...

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$100K - $120K *

Accelerate client success by owning the onboarding and rollout for enterprise clients, ensuring smooth transitions from purchase to sustained usage. Collaborate with cross-functional teams to drive ad...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$90K - $109K *

Lead the charge in executing high-priority Product and Technology initiatives across teams. Drive project delivery, manage stakeholder alignment, and enhance governance to achieve strategic business o...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$181K - $245K *

Elevate your career by leading lifecycle marketing strategies that enhance customer engagement, retention, and monetization. Drive impactful programs while managing a high-performing team and collabor...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$124K - $186K *

Empower enterprise growth by driving strategic account management for AI-native companies, guiding complex transformations, and fostering long-term partnerships through innovative DevSecOps solutions...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Innovate with us to transform manual workflows into efficient AI-driven solutions. As a Staff Forward Deployed Engineer, you'll collaborate closely with teams to streamline processes, enhancing produc...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$185K - $217K *

Unlock potential by leading the architecture and deployment of innovative AI/ML systems. Collaborate with stakeholders, mentor engineers, and drive technical strategies while ensuring operational exce...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $145K *

Lead the charge in delivering innovative AI and Agentforce solutions, managing implementation projects with a focus on customer success. Collaborate with teams to ensure strategic planning and executi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Transform the ScriptMed Cloud Platform by designing and deploying scalable solutions. Collaborate with teams to automate workflows and enhance customer onboarding while ensuring compliance with data s...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.