Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$75K - $95K *

Join a team that's redefining the annuities landscape by providing innovative solutions. As a key technical advisor, you'll collaborate with clients and internal teams to design impactful solutions th...

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$111K - $211K *

Advance your career by leading impactful research in public health and family planning. Drive data analysis and quality assurance efforts across low- and middle-income countries, collaborating with di...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$156K - $181K *

Elevate enterprise risk management by designing and executing data analytics solutions. Collaborate with stakeholders to enhance reporting processes and deliver insights that drive strategic decision...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Develop and manage scalable AI infrastructure solutions, ensuring secure access to foundation models. Collaborate with cross-functional teams to enhance platform capabilities and drive AI adoption whi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$88K - $118K *

Join us to analyze and document business and technical requirements, implement process improvements, and support ERP projects. Collaborate with teams to ensure accurate reporting and optimize system s...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$110K - $130K *

Champion customer solutions by rapidly prototyping and deploying AI-driven applications. Collaborate with cross-functional teams to enhance product capabilities and drive adoption, ensuring impactful...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$215K - $240K *

Shape the future of drug development by leading analytical strategies, ensuring compliance and optimization of processes across lifecycle stages, and collaborating with cross-functional teams and exte...

United StatesRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$120K - $170K *

Contribute to performance optimization by diagnosing shifts in a $30B portfolio. Leverage data insights to drive strategic recommendations, enhance client outcomes, and collaborate with cross-function...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$163K - $336K *

Advance product marketing strategies for automation solutions, leading a team to enhance advertiser performance through effective go-to-market execution and cross-functional collaboration, while simpl...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$88K - $114K *

Empower our marketing initiatives by leading automation solutions with Marketo. Collaborate with teams to design, implement, and optimize advanced marketing strategies, ensuring alignment with client...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$126K - $154K *

Unlock your potential as a Senior Accountant, driving financial accuracy and compliance. Collaborate across teams to enhance systems, oversee key accounting functions, and support audits in a dynamic...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the configuration and support of Infor M3 non-finance modules, driving business process analysis and continuous improvement. Collaborate with teams to ensure effective implementation and user tra...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$209K - $262K *

Transform customer AI workloads by leading the transition from proof-of-concept to production. Collaborate with engineering teams to ensure stable, scalable deployments while driving performance and c...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$50K - $114K *

Transform financial operations by driving budgeting, forecasting, and reporting processes. Collaborate with stakeholders to ensure accuracy and alignment in workforce planning, while supporting leader...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$160K - $185K *

Lead the charge in designing Azure platforms for healthcare data products, ensuring resilience, security, and cost management while mentoring engineers and shaping architectural standards in a fully r...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$225K - $281K *

Lead the charge in shaping detection and response strategies, driving hands-on initiatives to enhance security architecture and incident management. Collaborate across teams to ensure robust threat de...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $115K *

Transform data governance by leveraging your technical expertise in Collibra and data quality tools. Drive accuracy and reliability of data assets through hands-on implementation and analysis, ensurin...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$110K - $130K *

Join a dynamic team to create and implement control systems, providing technical support and mentoring while driving project success and ensuring optimal performance of HVAC and automation solutions...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$128K - $165K *

Lead reliability initiatives across complex systems, driving automation and observability. Collaborate with teams to enhance operational outcomes, manage incidents, and mentor engineers, ensuring comp...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Drive system reliability and scalability as a Senior Site Reliability Engineer, focusing on automation and collaboration with software teams to enhance performance and maintain service objectives acro...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$138K - $163K *

Lead and inspire software engineering teams to deliver innovative solutions, ensuring high-quality standards and alignment with business goals. Foster a collaborative culture while driving continuous...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$138K - $163K *

Drive the evolution of software solutions for healthcare quality reporting, leading engineering teams to deliver innovative, high-quality products while fostering a culture of collaboration and contin...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $240K *

Build innovative software solutions for federal partners, focusing on full-stack development, user experience, and secure integrations. Collaborate with cross-functional teams to deliver impactful app...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Join a team that's dedicated to optimizing privacy management processes and compliance technology. This role supports platform administration, user engagement, and operational improvements, ensuring e...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Join a team that's redefining application security by guiding customers through complex evaluations. Leverage your expertise in offensive security to build relationships, deliver impactful demos, and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.