Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$145K - $175K *

Innovate by designing and delivering advanced data and AI platforms on Databricks. Collaborate with clients and teams to shape solutions, optimize architectures, and drive successful implementations f...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$132K - $220K *

Join a team that's driving innovation in cloud technology and engineering excellence. Lead and mentor engineers while shaping strategic direction for Fan and Club products, ensuring high performance a...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Consumer Technology

$80K - $95K *

Analyze energy efficiency and demand response programs while collaborating with a diverse team. Utilize data analysis to provide insights, recommendations, and drive improvements for utilities across...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$98K - $157K *

Lead the charge in delivering cutting-edge technical solutions for energy systems. Collaborate with commercial teams to drive business growth and develop impactful field service proposals across a div...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $180K *

Transform biological imaging with your expertise in AI and microscopy. Collaborate with engineers and scientists to define expert reasoning, curate datasets, and build analysis pipelines that set the...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$183K - $220K *

Elevate technical storytelling by creating impactful demos and workshops that bridge the gap between product capabilities and customer understanding, empowering sales teams and enhancing buyer engagem...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$145K - $175K *

Unlock customer success by designing impactful journeys that enhance retention and revenue. As a key contributor, you'll shape service blueprints and orchestrate cross-functional teams to drive measur...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Elevate client success by managing complex projects, ensuring timely delivery, and maintaining budget integrity. Collaborate with diverse teams to drive engagement and optimize project outcomes from i...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$93K - $116K *

Empower integrated marketing campaigns with a focus on account-based marketing. Collaborate with Sales to prioritize accounts, align messaging, and drive pipeline growth while managing multi-channel c...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$94K - $157K *

Unlock potential by joining our team as a Data Analyst, where you'll leverage your expertise in data manipulation and visualization to support key Federal clients, driving impactful solutions through...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $170K *

Unlock potential by providing architectural engineering support for DOJ/BOP facilities. Collaborate on technical analyses, document reviews, and design recommendations to enhance decision-making and p...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$92K - $136K *

Help us drive customer success by owning and optimizing digital engagement programs. You'll lead strategy, build automated journeys, and analyze performance to enhance customer experiences and ensure...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Information Technology

$160K - $185K *

Unlock your potential by leading a dynamic team to drive channel partnerships, transforming opportunities into revenue-generating relationships across diverse verticals in a fast-growing ecosystem...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$88K - $105K *

Innovate in assay capability and control programs, leading data analysis and QC initiatives. Drive project milestones, enhance laboratory practices, and ensure compliance with industry standards while...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Elevate client success by crafting and optimizing innovative commerce media strategies. Leverage data-driven insights to enhance campaign performance across platforms, ensuring measurable growth and c...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$110K - $130K *

Join a team that's driving revenue growth by managing strategic corporate healthcare accounts, optimizing client satisfaction, and delivering measurable outcomes through expert relationship-building a...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$164K - $205K *

Lead the design and analysis of clinical validation studies, ensuring regulatory compliance and driving innovative research in molecular diagnostics. Collaborate with cross-functional teams to enhance...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$113K - $142K *

Elevate your career by joining our dynamic team to design, develop, and optimize bioinformatics software tools and systems, ensuring robust functionality and compliance in a fast-paced, innovative env...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$175K - $225K *

Transform data engineering practices by architecting scalable platforms, driving reliability, and mentoring teams. Lead cross-functional initiatives to enhance data governance and leverage AI tools fo...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$92K *

Join a transformative program to develop your Electrical & Automation skills through hands-on experience, mentorship, and structured training, preparing you for a full-time engineering role in a dynam...

6 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$140K - $175K *

Empower your career by driving impactful relationships in government sectors. Manage a dedicated account portfolio, enhance customer satisfaction, and lead strategic engagement initiatives to maximize...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$131K - $205K *

Engage in the design and evaluation of electric power generation projects. Provide technical support and owner’s engineering services, focusing on thermal power systems. Collaborate on project develop...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Technical Services

$75K - $126K *

Shape the future of talent acquisition by leading full-cycle recruitment for data and IT roles. Collaborate with hiring teams to enhance candidate experiences and drive continuous improvement in recru...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$120K - $160K *

Empower our Managed Services tooling ecosystem by designing integrations and automations. You'll lead the configuration of Jira Service Management, optimize alerting, and ensure seamless connectivity...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $105K *

Unlock potential by providing financial analysis and operational support for a complex government contract. Collaborate with leadership and teams to ensure effective budgeting, reporting, and subcontr...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.