Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$117K - $176K *

Accelerate progress at the forefront of electromechanical design, leading product development for circuit breakers. Collaborate across teams to ensure compliance, quality, and innovation while mentori...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$154K - $185K *

Join our dynamic team to develop next-gen storage solutions, enhancing Grafana's App Platform. Collaborate on innovative features, drive projects from ideation to operations, and contribute to an open...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $200K *

Join a team that's redefining operational efficiency by architecting robust internal tools and applying AI to real-world challenges. You'll lead technical direction, drive impactful decisions, and enh...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$80K - $95K *

Join a dynamic team as you drive continuous improvement initiatives, enhancing operational efficiency and fostering a culture of excellence across the organization. Collaborate with cross-functional t...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$111K - $167K *

Transform your career by leading clinical strategies and implementations, ensuring successful adoption of digital solutions while collaborating with diverse stakeholders to enhance patient safety and...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Business Services

$145K - $200K *

Lead the charge in delivering high-quality credit research on emerging market corporate issuers in Latin America, analyzing trends and providing actionable trade recommendations to enhance investment...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$124K - $155K *

Champion data-driven insights as you lead a multidisciplinary analytics team, driving client performance and strategic recommendations to enhance business growth and market competitiveness...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Join a dynamic team to design and implement scalable data processing pipelines, enhancing data flow and enabling faster analysis. Collaborate with cross-functional teams to translate business needs in...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $160K *

Engage with engineers to enhance developer workflows and tools. Own the product lifecycle from discovery to adoption, ensuring high-quality internal software that meets user needs and drives efficienc...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$107K - $132K *

Join a team that's shaping the future of cloud services and authentication systems. As a key contributor, you'll design, build, and maintain scalable, secure solutions while collaborating with cross-f...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$220K - $265K *

Lead the charge in building a high-performing mobile engineering team, driving technical execution and culture. Oversee multi-persona mobile experiences, architecture, and release operations, shaping...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Finance & Insurance

$135K - $160K *

Champion the design and delivery of modern data platforms, focusing on Microsoft Fabric and Azure. Lead client engagements, define architectures, and establish best practices for data solutions across...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Information Technology

$108K - $130K *

Unlock your potential by leading customer projects, ensuring seamless communication, and driving success in healthcare solutions. Collaborate with diverse teams to enhance client satisfaction and oper...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Drive success by leveraging your expertise in enterprise sales to enhance customer engagement and expand market presence. Collaborate cross-functionally to deliver innovative solutions that empower or...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Join a team that's redefining cloud solutions by architecting and delivering complex Azure engagements. Lead migrations, mentor engineers, and drive innovation while ensuring robust security and gover...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$145K - $193K *

Transform the marketing data landscape by leading the architecture and evolution of a scalable data platform. Drive innovation in analytics, AI, and operational frameworks to enhance marketing strateg...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$73K - $110K *

Drive coding quality and compliance by analyzing data, supporting audits, and enhancing documentation practices. Collaborate with teams to ensure accurate coding and adherence to regulatory standards...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$108K - $123K *

Shape the future of our SEO and AEO strategy by driving organic growth through innovative content mapping and AI-informed tactics. Collaborate across teams to enhance discoverability and ensure measur...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$165K - $253K *

Join a dynamic team to lead complex instrumentation and controls engineering projects in nuclear power. Drive innovation, ensure compliance, and enhance safety through digital upgrades and strategic c...

United StatesRemote

4 weeks ago

  •   15+ years exp.  •   Technical Services

$105K - $125K *

Transform coding quality and efficiency as a senior expert in radiology coding. Collaborate with cross-functional teams to enhance processes, provide guidance, and drive best practices, ensuring excep...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$77K - $108K *

Join a dynamic team to design and implement high-performance AI infrastructure solutions, ensuring client satisfaction through expert delivery and support of complex compute and storage systems for en...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$165K - $220K *

Join a team that's redefining avionics systems engineering by translating customer needs into innovative architectures and requirements. Collaborate across domains to deliver high-quality solutions in...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$100K - $124K *

Lead the charge in delivering impactful scientific software demonstrations and training. Collaborate with diverse teams to address customer needs and enhance bioinformatics solutions, driving innovati...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Lead the charge in programmatic media campaigns, driving strategy and execution for clients. Utilize your expertise to optimize performance, analyze data, and deliver exceptional communication and res...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Media

$95K - $115K *

Drive financial governance by tracking budgets, analyzing variances, and generating reports in a federal mission environment. Collaborate with cross-functional teams to ensure compliance and support e...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.