Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$179K - $248K *

Lead the charge in operationalizing strategy and driving cross-division initiatives. Collaborate with senior stakeholders to enhance efficiency and client satisfaction in a fast-paced corporate travel...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Lead a dynamic account management team, driving strategic relationships with major health systems. Foster high-touch engagement, ensuring customer success and operational excellence while directly man...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$160K - $230K *

Elevate your career by owning the infrastructure and security of a multi-environment platform. Collaborate with leadership to build and operate systems that support critical government operations and...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Join a dynamic team to drive enterprise sales within the Workday, SAP, or Coupa ecosystems. Leverage your relationships and expertise to navigate complex sales cycles, engage C-suite executives, and a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$138K - $184K *

Lead the charge in designing resilient electrical systems for mission-critical facilities. Collaborate with teams to oversee full-cycle electrical design, ensuring high availability and operational ex...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Technical Services

$70K - $196K *

Join a team that's redefining robotics innovation by developing scalable solutions for global industrial applications, enhancing efficiency and safety through cutting-edge technology and interdiscipli...

6 days ago

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Transform patient access by optimizing Epic Cadence workflows. Collaborate with clinical teams to enhance scheduling efficiency and support system improvements, ensuring seamless operations and superi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$170K - $220K *

Drive innovation by safeguarding AI systems while implementing robust security measures. Collaborate with diverse teams to ensure efficient AI integration and risk management, balancing security requi...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $160K *

Drive client success in our lab network by managing relationships, ensuring renewals, and identifying growth opportunities. Collaborate across teams to enhance processes and improve client experiences...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$190K - $267K *

Unlock potential by developing robust software solutions that enhance compliance and security programs. Collaborate across teams to automate processes, streamline workflows, and ensure timely risk man...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Media

$115K - $125K *

Champion the configuration of our Ascend 2.0 platform by leading spec negotiations and ensuring data quality for client onboarding. Collaborate cross-functionally, manage multiple implementations, and...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$128K - $214K *

Champion user research strategies that shape digital experiences by turning data into actionable insights, collaborating across teams to enhance user engagement and optimize web performance globally...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$193K - $308K *

Join a team that's redefining statistical leadership in clinical research. Drive innovative study designs, enhance drug development effectiveness, and influence critical decisions through data-driven...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $100K *

Join a team that's dedicated to ensuring sales compensation accuracy and integrity. You'll support deal desk operations and provide analytical insights, making a significant impact on revenue processe...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Empower your career by joining a dynamic SRE team focused on scaling Cloud services. Drive reliability, performance, and efficiency while leveraging your engineering skills to enhance infrastructure a...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$115K - $125K *

Empower your career by driving the integration and migration of data for a vital financial management system. Collaborate with experts to enhance system reliability and operational efficiency in a ful...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Transform healthcare insights by leading end-to-end quantitative market research. Collaborate with pharmaceutical teams to design impactful studies, analyze data, and deliver actionable recommendation...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Pioneer in search strategy, driving optimization across paid, organic, and AI channels. This role collaborates with cross-functional teams to enhance visibility, engagement, and customer acquisition t...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by serving as a top-tier technical expert, mentoring peers, and resolving complex challenges in customer success. Drive scalable processes and enhance team capabilities while engaging...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $165K *

Engage clients by driving revenue through consultative sales, building strong relationships with law firms and corporations. Leverage industry insights to anticipate needs and deliver tailored solutio...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$125K - $150K *

Grow your career with an innovative startup, driving strategic enterprise deals and cultivating key relationships with Fortune 1000 executives to showcase cutting-edge AI technology and deliver except...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Information Technology

$90K - $167K *

Unlock potential by driving revenue insights and financial modeling, enhancing decision-making across finance and operations. Collaborate with stakeholders to refine processes and improve revenue reco...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$139K - $235K *

Lead the development of innovative CX solutions using AI tools, enhancing workflows and integrations across platforms. Collaborate with cross-functional teams to deliver production-quality software an...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$85K - $100K *

Lead the execution and optimization of programmatic campaigns, fostering client relationships and mentoring team members to achieve strategic goals and enhance performance in a collaborative environme...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Media

$125K - $140K *

Elevate your career by designing and managing AWS environments, automating CI/CD, and ensuring robust application delivery. Collaborate with cross-functional teams for end-to-end ownership and enhance...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.