Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$110K - $130K *

Partner with us to drive data-informed marketing strategies and optimize measurement practices. Leverage your analytics skills to guide clients, enhance performance, and manage a talented team while f...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$218K - $273K *

Champion the global technical alliance with Snowflake and Databricks, driving co-sell revenue through strategic planning, technical narratives, and collaborative execution across teams and events, whi...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $125K *

Transform healthcare analytics by leading the development of APR-DRG audit criteria. Collaborate with cross-functional teams to enhance payment integrity through data-driven insights and innovative so...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$140K - $164K *

Join us to elevate brand presence by crafting engaging, real-time content across social platforms. Collaborate with teams to launch campaigns, analyze trends, and optimize strategies that resonate wit...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$106K - $147K *

Champion the development of ML pipelines, ensuring scalable, reliable decision-making systems that optimize member outcomes while collaborating with cross-functional teams to enhance platform performa...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Drive the enterprise adoption of AI capabilities, managing product strategy and governance for agent solutions. Collaborate across teams to ensure innovation aligns with security, compliance, and oper...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Business Services

$76K - $105K *

Support day-to-day operations for investment teams, collaborating across functions to enhance processes, manage budgets, and drive special projects from planning to implementation, ensuring alignment...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$172K - $202K *

Champion innovative insights and strategies as a Senior Director, driving impactful research and analysis to empower clients globally. Engage with stakeholders to deliver actionable advice and elevate...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Business Services

$223K - $290K *

Lead the technical strategy for data products, driving clinical data capabilities and insights. Collaborate with teams to optimize data ingestion processes and implement AI-assisted development workfl...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Healthcare

$98K - $109K *

Join a team that's dedicated to optimizing IT operations and ensuring compliance. You'll manage daily IT tasks, support security initiatives, and collaborate on maintaining audit readiness, all while...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$140K - $170K *

Lead the charge in optimizing our marketing technology ecosystem, ensuring seamless integration and support across platforms. Collaborate with cross-functional teams to translate business needs into e...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $185K *

Shape the future of data engineering by leading the architecture and evolution of a robust enterprise data platform, ensuring reliability and integration across analytics, reporting, and AI capabiliti...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Retail & Consumer Goods

$115K - $130K *

Join a team that's dedicated to developing innovative web and cloud applications. In this role, you'll lead projects, mentor junior engineers, and collaborate with cross-functional teams to deliver hi...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$169K - $267K *

Engage and drive net-new sales opportunities across industry accounts, managing a $32M+ annual target. Collaborate with ecosystem partners to deliver AI-driven solutions and ensure successful client o...

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$70K - $235K *

Join a team that's shaping the future of commerce through AI. You'll design and implement innovative AI solutions, ensuring seamless integration and scalability while collaborating with clients to dri...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Business Services

$180K - $190K *

Empower our team to drive innovation by developing crucial AI tools that enhance operational efficiency. Oversee governance, training, and metrics to ensure impactful adoption across departments while...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Business Services

$105K - $202K *

Innovate and build AI-native products that automate complex workflows. Collaborate with cross-functional teams to design, develop, and deploy full-stack applications, ensuring reliability and performa...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$165K - $339K *

Transform programmatic advertising by defining and scaling innovative products, collaborating across teams to enhance advertiser experiences while ensuring alignment with strategic business goals...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$185K - $260K *

Champion security excellence by designing and implementing robust software solutions. Collaborate with teams to enhance security practices, conduct code reviews, and respond to incidents, ensuring a s...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $160K *

Drive the development of LLM-based agents, ensuring robust production systems, effective evaluation, and seamless integration with company data while maintaining security and operational excellence ac...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Healthcare

$109K - $125K *

Unlock potential by transforming complex data into actionable insights that drive enterprise strategy and decision-making. Collaborate across teams to develop reporting tools and metrics that enhance...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$98K - $163K *

Explore innovative data solutions to enhance decision-making and operational efficiency for healthcare clients. Collaborate on analytics, machine learning, and application development to drive impactf...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$160K - $200K *

Shape the future of talent acquisition by driving full-cycle recruiting across commercial teams. Collaborate with leaders to build a high-performing workforce that aligns with our mission and values...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Join a team that's shaping the future of data platforms by building and operating high-scale distributed systems. Collaborate with engineers to enhance analytics capabilities and empower organizations...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $120K *

Drive financial excellence by collaborating across teams to enhance planning and reporting processes. This role blends detailed analysis with strategic insight, offering visibility into key leadership...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.