Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$113K - $191K *

Empower innovation in safety technology by developing AI-driven solutions that enhance customer experiences and operational efficiency. Collaborate across teams to deliver scalable, impactful products...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$153K - $226K *

Advance your career by owning and evolving our Workday platform, focusing on payroll and Core HCM. Collaborate with cross-functional teams to design scalable systems that enhance operational efficienc...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$117K - $157K *

Join a team that's transforming enterprise AI solutions through innovative design and deployment. Leverage your expertise to build secure, scalable AI platforms that enhance business processes and dri...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $170K *

Join a team that's transforming drug development through data science. Leverage your expertise to build predictive models and analytics, driving process improvements and technology transfer in a colla...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $200K *

Lead the charge in transforming business challenges into innovative solutions by leveraging your expertise in automation and integration. Collaborate across teams to enhance operational efficiency and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$230K - $280K *

Champion analytical development by leading strategy and execution for pipeline products. Drive compliance and quality control while building a high-performing team in a dynamic environment focused on...

United StatesRemote

Yesterday

  •   15+ years exp.  •   Information Technology

$132K - $271K *

Join us to lead pre-sales efforts, delivering impactful product demos and solutions. Collaborate with clients and partners to drive sales success, develop reusable assets, and enhance the pre-sales pr...

2 days ago

  •   8 - 10 years exp.  •   Business Services

$155K - $197K *

Innovate as a Tech Lead, driving architectural evolution and engineering execution for a global web platform. Collaborate with cross-functional teams to enhance digital experiences through advanced AI...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$170K - $185K *

Champion the development of scalable data platforms, leading cross-functional initiatives and enhancing AI-assisted analytics. Collaborate with teams to drive technical direction and improve system pe...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$120K - $130K *

Drive the transformation of customer data into automated reporting and AI tools, enhancing customer health tracking and executive visibility. Collaborate across teams to streamline workflows and ensur...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$152K - $210K *

Transform workforce data into actionable insights by leading People programs, systems, and analytics. Drive strategic initiatives, enhance operational efficiency, and foster a culture of continuous im...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$73K - $100K *

Elevate workforce planning by transforming data into impactful insights. Partner with leaders to build strategic forecasting tools and measure performance metrics, contributing to operational efficien...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in client strategy and Meta campaign management, ensuring optimal performance and strong relationships. Own a portfolio of accounts, drive results, and proactively solve issues to enha...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$118K - $180K *

Unlock potential by leading structural engineering reviews for renewable energy projects. Collaborate with multi-discipline teams to optimize design, support financing, and deliver actionable insights...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Technical Services

$135K - $160K *

Champion innovation in AI engineering by building intelligent systems that enhance productivity and streamline workflows, enabling teams to deliver exceptional user experiences and drive the future of...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Consumer Technology

$150K - $180K *

Lead the charge in driving enterprise sales by managing the full sales cycle, engaging with large organizations, and expanding relationships within the AI sector. Your expertise will be pivotal in est...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$128K - $252K *

Drive the evolution of people analytics by building data pipelines, dashboards, and insights that empower leaders with decision-ready information. Collaborate across teams to enhance data usability an...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$172K - $202K *

Innovate within identity and access management by providing expert insights and strategies to clients on best practices in identity governance, privileged access, and AI tools, enhancing cybersecurity...

RemoteRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Business Services

$131K - $200K *

Join a team that's shaping the future of data platforms by developing scalable solutions for analytics and AI workloads. Collaborate on impactful projects using cutting-edge tools to enhance data reli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$230K - $260K *

Lead the charge in client migrations, owning the entire technical lifecycle from legacy analysis to deployment, ensuring precision and collaboration across teams for optimal outcomes...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Information Technology

$139K - $222K *

Join a team that's shaping the future of housing market forecasting. Collaborate with experts to develop innovative models, extract key features, and communicate insights that drive strategic decision...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$95K - $192K *

Drive impactful data solutions by designing ETL pipelines, developing data models, and collaborating with analytics teams to support business objectives through data-driven insights and reporting...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$127K - $172K *

Unlock your potential by designing and optimizing Power BI reporting solutions that transform complex identity datasets into actionable insights, enhancing enterprise decision-making and compliance re...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$140K - $175K *

Empower scientific innovation by collaborating within product pods to develop and evaluate real-world evidence agents. Drive impactful research and ensure scientific rigor while partnering with indust...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$99K - $129K *

Shape the future of commercial analytics by delivering insights and automation that enhance decision-making and efficiency across the organization. Collaborate with stakeholders to drive impactful ini...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.