Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$265K - $295K *

Lead the charge in community engagement, fostering trusted relationships with local stakeholders to ensure Anthropic's infrastructure projects benefit Indiana and Kentucky communities throughout their...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $160K *

Transform data operations by leading our Snowflake platform migration, ensuring security, reliability, and cost efficiency while collaborating across teams to standardize practices and enhance data ma...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$80K - $95K *

Shape the future of data analytics by leveraging innovative technologies to develop scalable data products. Collaborate with cross-functional teams to ensure data quality and deliver actionable insigh...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Unlock potential by leading technical vision and mentoring engineers. Drive modernization and collaboration across teams to build resilient, scalable infrastructure while fostering a high-performance...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$147K - $217K *

Lead transformative analytics initiatives in life sciences, driving innovation and client success. Mentor teams, enhance measurement standards, and collaborate cross-functionally to deliver actionable...

RemoteRemote

4 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$80K - $95K *

Innovate post-acute payment integrity by developing and optimizing audit concepts for DME, home health, and infusion therapy claims. Collaborate cross-functionally to ensure compliance and enhance ope...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$184K - $356K *

Transform data processing architectures by optimizing performance and efficiency. Collaborate with diverse teams to enhance user experiences and drive innovation in hardware-software co-design for cut...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$242K - $285K *

Transform the customer success landscape by leading technical teams, driving integration health, and enhancing revenue through strategic partnerships and innovative solutions in the programmatic ecosy...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Media

$160K - $280K *

Join us to architect and build a cutting-edge web platform, driving marketing innovation through AI agents. Own technical decisions, enhance user experiences, and ensure seamless integration with our...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $100K *

Unlock your potential by contributing to enterprise EDI and integration projects. Collaborate with experienced engineers to design, implement, and optimize solutions, enhancing customer satisfaction a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$170K - $200K *

Transform customer experiences by providing technical expertise and solutions. Collaborate with sales and engineering teams to deliver impactful product demonstrations and address technical challenges...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $140K *

Innovate cloud solutions by designing and automating infrastructure in Cloud.gov and Azure. Collaborate with teams to enhance performance and security, driving impactful results for clients while shap...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Innovate AI-driven business applications by designing Python services and APIs that enhance data processing capabilities in both cloud and on-premises settings, ensuring robust performance and seamles...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Technical Services

$86K - $107K *

Lead advanced analytics projects that drive strategic decisions, optimize sales productivity, and enhance operational efficiency. Collaborate with executives to deliver data-driven insights and implem...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$79K - $122K *

Shape the future of IT capabilities by leading requirements analysis and advisory support for a Department of War agency. Collaborate with stakeholders to deliver data-driven insights and enhance ente...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$232K - $325K *

Join a dynamic team to lead the development of advanced analytics tools, leveraging your expertise in statistics and machine learning to drive impactful decision-making across the organization...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Media

$125K - $150K *

Transform business workflows by developing and maintaining applications that enhance productivity and information sharing across teams. Collaborate with IT and business units to deliver innovative sol...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Technical Services

$110K - $130K *

Unlock potential by designing and delivering scalable AI-powered integrations for nonprofits. Collaborate closely with clients to understand their needs, build solutions, and productize offerings that...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $131K *

Transform complex data into actionable insights, partnering with leaders to enhance strategic decision-making and drive organizational performance through advanced analytics and reporting frameworks...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$200K - $215K *

Drive innovation in data engineering and AI solutions, leading the design and deployment of scalable systems. Collaborate with cross-functional teams to enhance business value through advanced technol...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $145K *

Champion data excellence by designing and optimizing scalable data platforms. Collaborate with cross-functional teams to enhance performance and drive innovation in data processing, ensuring alignment...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$149K - $185K *

Lead the strategy and execution of paid digital advertising programs, optimizing campaigns across multiple channels to drive measurable pipeline and revenue impact. Collaborate with cross-functional t...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $145K *

Lead the charge in building and delivering data products that empower leadership and client engagements. This hands-on role requires strategic oversight and collaboration to ensure high-quality analyt...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$84K - $120K *

Accelerate insights generation as a key member of the Customer Analytics team, transforming raw data into actionable recommendations that enhance client retention, drive growth, and refine operational...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$106K - $141K *

Join a team that's building an AI-ready data foundation for marketing and GTM. You'll design, govern, and analyze data models, ensuring reliable insights for strategic decision-making across the organ...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.