Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Consultant, Scientific and Laboratory Informatics
$70K - $205K *
Innovate digital laboratory operations by delivering strategic solutions that enhance scientific intelligence and user experiences, while collaborating with clients to transform their data-driven envi...
Yesterday
Staff Machine Learning Engineer(Platform - Identity)
$218K - $256K *
Lead the end-to-end execution of ML systems for identity verification, ensuring the integrity of millions of accounts through advanced models and cross-team collaboration, while mentoring engineers an...
Reposted 1 week ago
$154K - $232K *
Transform enterprise cloud strategies by leading large-scale migrations to Azure and AWS. Collaborate with global teams to establish architecture standards, ensure security, and drive innovative solut...
6 days ago
$90K - $110K *
Unlock potential by enhancing revenue operations through data-driven workflows, improving systems, and automating processes. Collaborate with cross-functional teams to ensure efficiency and scalabilit...
2 weeks ago
$127K - $224K *
Drive impactful product modeling and marketing measurement as a Staff Data Scientist. Own the lifecycle of ML models, collaborate with PMs, and communicate insights effectively to enhance user experie...
Yesterday
$160K - $180K *
Unlock potential by leading product marketing initiatives that empower healthcare teams. Drive sales enablement, module marketing, and customer expansion, while shaping messaging and content that reso...
4 weeks ago
Lead Forward Deployed Engineer (AI Enablement)
$194K - $272K *
Elevate AI solutions by leading engineering efforts that transform business workflows. Collaborate with teams to identify opportunities, prototype solutions, and implement scalable AI applications tha...
2 weeks ago
Senior Software Engineer, AI Automation
$130K - $195K *
Join a dynamic AI Automation team to design and deliver production-grade AI agents and workflows, enhancing operational efficiency across the organization while solving complex business challenges wit...
1 week ago
$84K - $87K *
Join us as a Data Operations Engineer, where you'll develop and manage data systems for healthcare claims processing. Collaborate with teams to ensure data accuracy and optimize ETL/ELT pipelines whil...
Reposted 3 weeks ago
Director of Data Analytics and Governance
$80K *
Empower the future of data-driven decision-making by leading institutional research and analytics. Transform complex data into actionable insights to enhance student success and operational efficiency...
4 weeks ago
$156K - $180K *
Empower clients by owning technical relationships for the Enterprise Suite, guiding them from discovery to implementation. Collaborate with teams to enhance adoption and resolve issues, ensuring seaml...
2 weeks ago
Manager, Software Engineering - Engineering Tools
$120K - $148K *
Join a team that's shaping the future of AEC software by leading engineering talent and enhancing workflows. Drive innovation in Autodesk Revit add-ins and tools while fostering a collaborative enviro...
2 weeks ago
Senior AI Product Engineer, Backend
$125K - $225K *
Join a team that's driving innovation in AI by developing scalable backend systems in Go, Python, and Java. Tackle complex challenges while enhancing distributed architectures to empower high-performa...
Reposted 6 days ago
$60K - $120K *
Unlock potential by deploying and supporting advanced robotic systems in diverse environments. Collaborate with teams, troubleshoot issues, and enhance client experiences through effective communicati...
4 weeks ago
$135K - $160K *
Engage in designing and optimizing AI solutions to enhance automation and analytics, collaborating across teams to integrate advanced AI capabilities into core products, while ensuring ethical standar...
1 week ago
$145K - $165K *
Drive your career by owning the end-to-end data platform, designing and maintaining scalable pipelines and infrastructure. Collaborate with analytics teams to ensure data quality and governance while...
2 weeks ago
$140K - $160K *
Unlock potential by driving the evolution of AWS environments and CI/CD pipelines, enhancing observability and security, while collaborating with engineers to optimize platform reliability and perform...
1 week ago
$150K - $185K *
Unlock potential by driving innovative infrastructure solutions for scalable deployments, collaborating with customers to refine requirements, and enhancing operational efficiency through automation a...
Reposted 6 days ago
Manager, Software Engineering - AI Tools
$120K - $150K *
Join a team that's shaping the future of AI engineering by leading a dynamic group of engineers and Technical Leads. Drive workforce strategy, enhance team capabilities, and ensure sustainable deliver...
2 weeks ago
Account Director, Medical Imaging and SS
$110K - $130K *
Advance your career by driving business development in clinical research and medical imaging. Build strategic client relationships, identify new opportunities, and contribute to innovative healthcare...
Reposted 3 weeks ago
Data Analytics Manager - Client Legal Services
$100K - $170K *
Drive the evolution of Legal Operations analytics by building scalable data capabilities, modernizing reporting, integrating AI, and establishing predictive models to enhance decision-making and opera...
Reposted 1 week ago
Senior/Staff Full Stack Software Engineer, Frontend Leaning
$135K - $160K *
Elevate user experiences by leading the development of innovative web features. Collaborate with cross-functional teams to deliver high-quality, customer-facing applications using modern technologies...
1 week ago
Director, Advanced Analytics & Modeling Key Drivers Analytics (KDA) and CoE Lead
$194K - $361K *
Lead the charge in Advanced Analytics & Modeling, driving enterprise Key Drivers Analytics and managing a talented team to deliver impactful insights and solutions across diverse business challenges...
5 days ago
$80K - $95K *
Empower clients by leading data transitions to e-Automate, ensuring timely, high-quality implementations. Collaborate with teams to enhance processes and deliver tailored solutions that meet diverse b...
1 week ago
$130K - $160K *
Transform business challenges into innovative solutions by leveraging AI and engineering expertise. Collaborate with stakeholders to identify opportunities, develop full-stack applications, and drive...
1 week ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.