Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$180K - $225K *

Elevate the future of AI systems by architecting LLM-powered workflows that enhance customer interactions, ensuring security and performance while guiding teams through complex challenges and deliveri...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

$90K - $110K *

Unlock potential by leading the functional support and improvement of business systems for Legal, Procurement, Safety, and Environmental teams, ensuring effective use and resolution of issues while en...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$466K - $500K+*

Join a team that's shaping the future of AI by designing and building scalable platforms for large-scale machine learning model training, enhancing performance, and creating user-friendly experiences...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$218K - $256K *

Elevate compliance operations by architecting AI systems that automate workflows, ensuring accuracy and regulatory adherence while mentoring engineers and driving technical excellence in machine learn...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$115K - $130K *

Drive client growth by leveraging data-driven insights to enhance strategic relationships and deliver impactful solutions. Collaborate cross-functionally to achieve measurable outcomes and ensure clie...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$105K - $163K *

Transform database environments by leading architecture and administration efforts across multiple platforms, ensuring compliance and performance for mission-critical applications in a dynamic, remote...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$160K *

Drive the future of project controls by providing expert EVM, cost, and schedule analysis for federal programs. Collaborate with cross-functional teams to enhance decision-making and ensure program co...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$125K - $160K *

Join a team that's redefining data solutions by leading technical sales efforts, collaborating with Account Managers, and driving customer success through innovative data architecture and tailored dem...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$105K - $231K *

Shape the future of AI/ML by designing innovative computer vision solutions. Collaborate with cross-functional teams to deliver impactful software applications while leveraging cutting-edge technologi...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$94K - $266K *

Lead the charge in transforming customer engagements by managing AWS solutions delivery, ensuring client satisfaction, and driving strategic growth through strong relationships and innovative practice...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$180K - $200K *

Lead complex technical initiatives, ensuring scalable, secure solutions while mentoring engineers and driving high standards across the software development lifecycle in a remote, collaborative enviro...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Media

$135K - $160K *

Lead a dynamic team to transform AI strategies into impactful healthcare solutions. Oversee engineering execution, guide architecture, and ensure compliance while collaborating with cross-functional p...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Transform the quality landscape of data center equipment by overseeing supplier audits, inspections, and continuous improvement initiatives. Collaborate with cross-functional teams to ensure complianc...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Explore the complexities of Russian and Eurasian crypto threats, owning end-to-end attribution and analysis. Collaborate with a global team to produce actionable intelligence and represent expertise i...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$128K - $187K *

Create robust machine learning systems to transform satellite imagery into reliable data. Collaborate with experts to design scalable solutions, build data pipelines, and develop models that enhance g...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$125K - $145K *

Lead the charge in building impactful software features that enhance educators' management of English Learner programs, taking ownership from design to operation in a full-stack environment utilizing...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Drive building performance and energy efficiency by conducting assessments, audits, and evaluations for diverse properties. Collaborate with clients to enhance sustainability and reduce operational co...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$131K - $165K *

Elevate AI capabilities by designing, developing, and deploying innovative AI solutions that enhance products and processes. Collaborate across teams to ensure scalable, secure, and responsible applic...

Cedar Rapids, IARemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$131K - $165K *

Elevate your career by designing and deploying innovative AI solutions that enhance products and processes. Collaborate across teams to deliver scalable, secure applications while mentoring junior eng...

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$165K - $243K *

Lead the charge in data engineering excellence by mentoring a team, driving pipeline delivery, and translating stakeholder needs into actionable technical plans while ensuring operational accountabili...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Information Technology

$105K - $125K *

Join as a hands-on analytics specialist, leveraging Amazon data to drive insights and support decision-making for clients. Collaborate with teams to optimize performance and enhance reporting across v...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Media

$100K - $120K *

Join us to drive impactful data analysis that enhances product performance and operational effectiveness. Collaborate with cross-functional teams to uncover insights, develop KPIs, and translate compl...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$192K - $266K *

Drive best-in-class travel support through strategic leadership and operational excellence. Oversee lodging, flights, and customer advocacy, fostering a culture of continuous improvement and exception...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$110K - $130K *

Lead the charge in market intelligence and sales support, bridging teams to drive insights and strategies in U.S. power markets. Collaborate cross-functionally to identify opportunities and enhance cu...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$217K - $303K *

Innovate with us to lead a high-performing engineering team, shaping a scalable AI-powered knowledge graph platform that enhances data quality and drives impactful user experiences across multiple app...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Media

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.