Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Senior AI Engineer (CCC Auto / Agentic)
$180K - $225K *
Elevate the future of AI systems by architecting LLM-powered workflows that enhance customer interactions, ensuring security and performance while guiding teams through complex challenges and deliveri...
Today
$90K - $110K *
Unlock potential by leading the functional support and improvement of business systems for Legal, Procurement, Safety, and Environmental teams, ensuring effective use and resolution of issues while en...
6 days ago
Software Engineer 5 - Training Platform, AI Platform
$466K - $500K+*
Join a team that's shaping the future of AI by designing and building scalable platforms for large-scale machine learning model training, enhancing performance, and creating user-friendly experiences...
1 week ago
Staff Machine Learning Engineer, Compliance Automation (Platform)
$218K - $256K *
Elevate compliance operations by architecting AI systems that automate workflows, ensuring accuracy and regulatory adherence while mentoring engineers and driving technical excellence in machine learn...
1 week ago
$115K - $130K *
Drive client growth by leveraging data-driven insights to enhance strategic relationships and deliver impactful solutions. Collaborate cross-functionally to achieve measurable outcomes and ensure clie...
2 weeks ago
$105K - $163K *
Transform database environments by leading architecture and administration efforts across multiple platforms, ensuring compliance and performance for mission-critical applications in a dynamic, remote...
3 weeks ago
Senior Project Controls Analyst
$160K *
Drive the future of project controls by providing expert EVM, cost, and schedule analysis for federal programs. Collaborate with cross-functional teams to enhance decision-making and ensure program co...
2 days ago
Senior Sales Engineer, Data Products
$125K - $160K *
Join a team that's redefining data solutions by leading technical sales efforts, collaborating with Account Managers, and driving customer success through innovative data architecture and tailored dem...
1 week ago
AI/ML Engineer (Computer Vision)
$105K - $231K *
Shape the future of AI/ML by designing innovative computer vision solutions. Collaborate with cross-functional teams to deliver impactful software applications while leveraging cutting-edge technologi...
Today
$94K - $266K *
Lead the charge in transforming customer engagements by managing AWS solutions delivery, ensuring client satisfaction, and driving strategic growth through strong relationships and innovative practice...
3 weeks ago
$180K - $200K *
Lead complex technical initiatives, ensuring scalable, secure solutions while mentoring engineers and driving high standards across the software development lifecycle in a remote, collaborative enviro...
2 days ago
$135K - $160K *
Lead a dynamic team to transform AI strategies into impactful healthcare solutions. Oversee engineering execution, guide architecture, and ensure compliance while collaborating with cross-functional p...
1 week ago
Manufacturing Quality Engineer, Data Center Equipment
$110K - $130K *
Transform the quality landscape of data center equipment by overseeing supplier audits, inspections, and continuous improvement initiatives. Collaborate with cross-functional teams to ensure complianc...
5 days ago
Senior Intelligence Analyst - Russia & Eurasia Regional Focus
$120K - $145K *
Explore the complexities of Russian and Eurasian crypto threats, owning end-to-end attribution and analysis. Collaborate with a global team to produce actionable intelligence and represent expertise i...
Reposted 1 week ago
$128K - $187K *
Create robust machine learning systems to transform satellite imagery into reliable data. Collaborate with experts to design scalable solutions, build data pipelines, and develop models that enhance g...
3 weeks ago
Software Engineer II, Engineering
$125K - $145K *
Lead the charge in building impactful software features that enhance educators' management of English Learner programs, taking ownership from design to operation in a full-stack environment utilizing...
Reposted 2 weeks ago
$80K - $95K *
Drive building performance and energy efficiency by conducting assessments, audits, and evaluations for diverse properties. Collaborate with clients to enhance sustainability and reduce operational co...
Today
$131K - $165K *
Elevate AI capabilities by designing, developing, and deploying innovative AI solutions that enhance products and processes. Collaborate across teams to ensure scalable, secure, and responsible applic...
2 weeks ago
$131K - $165K *
Elevate your career by designing and deploying innovative AI solutions that enhance products and processes. Collaborate across teams to deliver scalable, secure applications while mentoring junior eng...
2 weeks ago
$165K - $243K *
Lead the charge in data engineering excellence by mentoring a team, driving pipeline delivery, and translating stakeholder needs into actionable technical plans while ensuring operational accountabili...
Reposted 2 days ago
Senior Manager, Insights, Amazon Focus
$105K - $125K *
Join as a hands-on analytics specialist, leveraging Amazon data to drive insights and support decision-making for clients. Collaborate with teams to optimize performance and enhance reporting across v...
Yesterday
$100K - $120K *
Join us to drive impactful data analysis that enhances product performance and operational effectiveness. Collaborate with cross-functional teams to uncover insights, develop KPIs, and translate compl...
4 weeks ago
Senior Director, Client Operations
$192K - $266K *
Drive best-in-class travel support through strategic leadership and operational excellence. Oversee lodging, flights, and customer advocacy, fostering a culture of continuous improvement and exception...
Reposted 2 weeks ago
Manager, Market Intelligence & Commercial Analytics
$110K - $130K *
Lead the charge in market intelligence and sales support, bridging teams to drive insights and strategies in U.S. power markets. Collaborate cross-functionally to identify opportunities and enhance cu...
3 weeks ago
Engineering Manager, Knowledge Graph Platform
$217K - $303K *
Innovate with us to lead a high-performing engineering team, shaping a scalable AI-powered knowledge graph platform that enhances data quality and drives impactful user experiences across multiple app...
4 weeks ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.