Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$80K - $95K *

Drive impactful decision-making and support for EHRM initiatives, enhancing operational efficiency and stakeholder engagement through strategic analysis, project management, and effective communicatio...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$155K - $410K *

Unlock potential by leading AI-driven data solutions that transform insights into business growth. Collaborate with executive clients, spearhead innovative projects, and mentor future leaders while sh...

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Legal & Accounting

$172K - $203K *

Elevate women's health outcomes by developing advanced machine learning models. Lead projects, mentor junior team members, and collaborate with cross-functional teams to drive innovation and commercia...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$92K - $110K *

Deliver strategic leadership and operational oversight to enhance decision-making processes within the Veterans Health Administration's EHRM, ensuring effective collaboration and communication across...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$83K - $140K *

Innovate financial strategies by partnering with R&D leaders to optimize costs, enhance reporting frameworks, and drive accurate forecasting in a dynamic environment. Your analytical skills will shape...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$171K - $190K *

Unlock potential by leading the design and implementation of scalable data platforms. Drive innovation in cloud data architecture and pipeline automation, collaborating across teams to deliver impactf...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$119K - $139K *

Develop robust data solutions and pipelines using Azure technologies, ensuring data quality and governance. Collaborate with stakeholders to translate business needs into technical solutions, enhancin...

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$119K - $139K *

Champion the development of innovative data solutions, leveraging Azure pipelines to create robust data assets. Collaborate with stakeholders to translate complex requirements into effective technical...

North Liberty, IARemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Join us to manage and enhance our consumer purchase data assets, collaborating with vendors and internal teams to ensure high-quality data acquisition and compliance, driving insights and analytics fo...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Elevate customer insights by analyzing complex data to drive retention strategies. Collaborate with senior leaders to present actionable recommendations that enhance customer experience and operationa...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $145K *

Transform complex data systems by designing and implementing scalable solutions that enhance analytics and drive business intelligence in a collaborative, Agile environment focused on healthcare compl...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$158K - $170K *

Lead the development of predictive models integrating advanced ML techniques to drive strategic decision-making across credit risk, collections, and business operations while mentoring data scientists...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$188K - $235K *

Develop AI-powered systems from concept to production, collaborating with clients to identify needs, prototype solutions, and ensure quality. Engage closely with users to iterate and enhance product f...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$180K - $225K *

Join a team that's redefining AI in auto claims by building and evaluating machine learning models. You'll drive product decisions through data insights, collaborating with experts to enhance claims p...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Business Services

$125K - $150K *

Join a team that's shaping the future of machine learning by leveraging traditional algorithms and financial data. Collaborate with clients to design, build, and optimize innovative solutions while ad...

Des Moines, IARemote

Reposted yesterday

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Optimize machine learning solutions by leveraging traditional algorithms and financial data. Collaborate with clients to enhance product delivery and integrate seamlessly into teams, driving impactful...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Engineer scalable Azure data solutions, leading architecture and modernization initiatives. Collaborate with teams to define standards and ensure high-performance data integration, governance, and sec...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$128K - $170K *

Engineer robust pipelines to transform raw conversation data into structured customer memory, ensuring accuracy and efficiency in retrieval systems while collaborating with cross-functional teams to e...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Transportation

$194K - $361K *

Reimagine your career by leading advanced analytics initiatives that drive enterprise performance. Collaborate across functions to translate insights into strategic actions, enhancing growth and marke...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$207K - $244K *

Elevate pricing strategies as you lead experimentation efforts, collaborate with cross-functional teams, and deliver actionable insights to enhance decision-making and drive business growth through da...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$300K - $350K *

Engage in a dynamic sales role, driving the full cycle from pipeline generation to closing six-figure deals in mid-market and enterprise cybersecurity. Contribute to go-to-market strategies and build...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $159K *

Lead the charge in transforming audience intelligence through innovative product strategies, enhancing consumer insights and data-driven solutions for brands and partners while ensuring privacy and co...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$166K - $230K *

Innovate and enhance the machine learning infrastructure to empower rapid model deployment and automation. Collaborate across teams to streamline operations and drive impactful solutions in ML and fin...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $155K *

Transform data into actionable insights by leading research initiatives, collaborating with business leaders, and developing predictive models to drive strategic decisions and enhance product offering...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$101K - $113K *

Advance your career by transforming complex data into actionable insights that drive financial and operational success. Collaborate with executives to solve high-impact data challenges and develop sca...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.