Job DescriptionGeneral Summary:The successful candidate will work in a team setting and be responsible for coordinating production of program-relevant cell types such as stem cell-derived islets (SC-islet) for use across research team projects. This includes 2D and 3D culture of pluripotent stem cells as well as differentiation for in vitro and in vivo studies. A demonstrated strong understanding of best lab practices to ensure reliability, consistency, efficiency, and quality control, as well as dedication to lab bench work, are required.
Key Duties and Responsibilities:- Culture human stem cells in 2D and/or 3D
- Completes experiments in a reliable, consistent manner
- Demonstrates a high level of attention to detail and follows SOP strictly
- Performs initial analysis of experimental data and interprets immediate experimental outcomes
- Records experiments and results in laboratory notebooks (including all electronic systems) in accordance with lab procedures
- Recognizes problems and suggests experiments to troubleshoot issues
- Develops new ideas to improve workflows, consistency and efficiency of the cell culture processes
- Clearly and effectively communicates (both written and verbal) results
Knowledge and Skills:- Experience with advanced human cell culture techniques
- Teachable mindset capable of learning protocols to execute stem cell differentiations producing consistent high-quality product
- Ability and willingness to work rotating weekend shifts according to business needs
- Adaptive to a time-line driven work environment
- Multitasking skills, attention to details and ability to work in a collaborative team environment
- Work with cross-functional teams to plan, coordinate, and execute experiments.
- Great interpersonal/teamwork skills and positive attitude
- Proven technical proficiency and demonstrated skill in conducting and interpreting experiments including the development of human stem cell models and assays to evaluate targets and lead molecules for Vertex diseases.
- Uses technical knowledge to design and execute follow-up experiments
Education and Experience:- Masters Degree (or equivalent degree) in biological sciences and 0-2 years of relevant employment experience, or
- Bachelors Degree (or equivalent degree) in biological sciences and 4+ years of relevant employment experience
Pay Range:$74,800 - $112,200
Disclosure Statement:The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.
Flex Designation:On-Site Designated
Flex Eligibility Status:In this
On-Site designated role, you will work
five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.
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