23andMe sits on one of the largest and most scientifically rich genetic datasets in the world. We're looking for a Senior Software Engineer to help build and operate the systems that make that data meaningful - powering everything from ancestry features and DNA relatives to health insights and machine learning pipelines that serve millions of customers.
Our Engineering team is based in the San Francisco Bay Area, CA, and this position will follow our hybrid work model.
What You'll Do- Design, build, and operate the backend services and data stores that turn raw genetic data into customer-facing results at scale
- Leverage AI tooling to automate testing, accelerate feature delivery, and ship with confidence through robust CI/CD pipelines
- Partner with product, science, and engineering teams to translate requirements into reliable, scalable systems
- Build AI-powered data pipelines that deliver personalized health and ancestry insights directly to customers
- Debug production incidents and get services back online: you'll own what you ship
What You'll Bring- B.S. in Computer Science or equivalent; 4+ years of industry experience
- Deep, hands-on Python: libraries, services, data pipelines
- Infrastructure as code experience, ideally in Terraform on AWS, containerized in Docker
- Hands-on experience working with CI/CD deployment pipelines and testing frameworks
- Experience operating distributed systems at scale: debugging, observability, performance tuning
What We OfferA small, high-trust team with real ownership, autonomy, and direct impact on one of the most scientifically rich datasets in the world. You'll work at the intersection of software engineering and cutting-edge genetic research without needing to be a scientist yourself. Our R&D and bioinformatics teams own the science; your job is to make it production-ready and scalable, supported by some of the sharpest minds in genomics who are excited to bring you up to speed. We're an AI-friendly team that actively uses coding tools like Claude Code to help engineers do their best work. You'll ship multiple times per week, work with some of the sharpest minds in genomics, and build systems that matter to millions of people.
Pay Transparency23andMe takes a market-based approach to pay, and amounts will vary depending on your geographic location. The salary range reflected here is for a candidate based in the San Francisco Bay Area. The successful candidate's starting pay will be determined based on job-related skills, experience, qualifications, work location, and market conditions. These ranges may be modified in the future.
San Francisco Bay Area Base Pay Range
$160,000-$200,000
