Job Function:
Supply Chain Engineering
Job Sub Function:
Process Engineering
Job Category:
Scientific/Technology
All Job Posting Locations:
Gurabo, Puerto Rico, United States of America
Job Description:
About Innovative Medicine
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way!
Learn more at
We are searching for the best talent for a Sr Principal Eng - Process Engineering to join our Team! This is an onsite/hybrid role.
Please note that this role is available across multiple countries and may be posted under different requisition numbers to align with local requirements. While you are welcome to apply to any or all of the postings, we recommend focusing on the specific country(s) that align with your preferred location(s):
Belgium & Italy- Requisition Number: R-071736
Puerto Rico - Requisition Number: R-076777
Switzerland - Requisition Number: R-076783
Remember, whether you apply to one or all of these requisition numbers, your applications will be considered as a single submission.
Position Summary
As the GET PE – Synthetics Drug Product Manufacturing Senior Principal Engineer, you will lead early design inputs and technical strategy for synthetic’s drug product manufacturing processes within strategic capital projects, network studies, and technology platforms across IMSC. You will provide deep technical expertise in the synthetic’s controlled bioburden-drug product manufacturing (OSD and innovative forms such as semi-solid)and drug product intermediate through bioavailability enhanced technologies, while supporting solving and optimization activities at internal and external manufacturing sites.
Joining our global engineering group, you will collaborate with high‑performing, multi-functional teams across multiple sites and functions. This role offers a dynamic and inspiring work environment with significant opportunities to influence technology direction, standardization, and capability building across the network.
Responsibilities and impact you will have:
Lead the intake, scoping, prioritization, and resolution of syntheticscontrolled bioburden- drug product manufacturing related technical requests across global sites
Lead and influence early‑phase process design and domain expertise for oral solid dose (OSD) products, covering both batch and continuous manufacturing platforms; as well new innovative drug product forms
Lead and influence early‑phase process design and domain expertise for bioavailability enhanced technologies, including amorphous solid dispersions (ASD) with a strong emphasis on spray drying, as well as other technologies such as and other related innovative drug product intermediate formulation approaches
Ensure robust, fit‑for‑purpose process design while promoting standardization and platform approaches where they make valuable contributions
Provide expert input and alignment on key process, equipment, and technology selection decisions for drug product manufacturing
Actively collaborate with other functions such as R&D, MSAT, Quality, EHS and Operations leads across synthetic drug product sites
Find opportunities for harmonization, shared solutions, and best‑practice exchange across the network
Foster a culture of collaboration to reduce duplication, accelerate implementation, and improve speed‑to‑market
Maintain strong connections with industry experts and external networks (e.g., ISPE) to bring innovative drug product manufacturing solutions into the organization
Ensure alignment with enterprise strategies, GMP requirements, and technology roadmaps
Collaborate with External Manufacturing teams to prioritize support and resolve issues for high‑impact programs and partners
Qualifications
Required:
Education:
Experience and Skills:
Minimum 10 years of relevant experience in synthetics controlled bioburden drug product manufacturing, with a strong focus on oral solid dose (OSD) processes and innovative technologies (e.g semi-solid) in drug product pharmaceutical manufacturing environments
Demonstrated expertise in bioavailability enhanced technologies, including ASD (amorphous solid dispersions)—with deep knowledge of spray drying—and SEDDS or similar innovative enabling formulation approaches
Proven experience with OSD controlled bioburden manufacturing, including batch and continuous manufacturing processes and associated equipment
Strong understanding of cGMP environments and regulatory expectations for controlled bioburden-drug product manufacturing. Aseptic capability is a plus
Proven track record of leading multi-functional teams and influencing technical decisions in complex, global organizations
Ability to support early‑phase design, detail design, Start‑up processes and Commissioning & Qualification (C&Q) of controlled bioburden (and aseptic) equipment
Experience with inherently safe containment design for components with low exposure level
Drive the adoption of digital and data‑enabled solutions for DP manufacturing, including real‑time monitoring, advanced process control, advanced analytics, model and simulation, and smart manufacturing use cases where they improve reliability and performance
Strong customer management and communication skills, with the ability to influence across sites, functions, and external partners
Strategic attitude combined with hands‑on technical capability
Intellectual curiosity to challenge the status quo, influence without authority, and cultivate an inclusive and collaborative culture
Proficiency in written and spoken English
Willingness to travel up to 25% domestically and internationally
Preferred:
Strategic attitude combined with hands‑on technical capability
Intellectual curiosity to challenge the status quo, influence without authority, and cultivate an inclusive and collaborative culture
Additional languages (Dutch, Spanish, Italian) are an advantage
Required Skills:
Preferred Skills:
Agile Decision Making, Coaching, Consulting, Corrective and Preventive Action (CAPA), Crisis Management, Cross-Functional Collaboration, Disruptive Innovations, Emerging Technologies, Industrial Hygiene, Lean Supply Chain Management, Process Control, Process Engineering, Product Costing, Program Management, Project Schedule, Science, Technology, Engineering, and Math (STEM) Application, Tactical Planning, Technical Credibility, Technical Research
The anticipated base pay range for this position is :
$116,000.00 - $200,100.00
Additional Description for Pay Transparency:
Subject to the terms of their respective plans, employees are eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).
Subject to the terms of their respective policies and date of hire, employees are eligible for the following time off benefits:
• Vacation –120 hours per calendar year
• Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado –48 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year
• Holiday pay, including Floating Holidays –13 days per calendar year
• Work, Personal and Family Time - up to 40 hours per calendar year
• Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child
• Bereavement Leave – 240 hours for an immediate family member: 40 hours for an extended family member per calendar year
• Caregiver Leave – 80 hours in a 52-week rolling period10 days
• Volunteer Leave – 32 hours per calendar year
• Military Spouse Time-Off – 80 hours per calendar year
Additional information can be found through the link below.
For additional general information on Company benefits, please go to: - https://www.careers.jnj.com/employee-benefits
