Biodesix

Senior Technology & Business Risk Manager

Biodesix$145K — $160K *
Enterprise Technology
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in IT, Cybersecurity, Risk Management, or related field
  • 8+ years of experience in IT Risk Management or related disciplines
  • 5+ years of leadership experience in risk or compliance management
  • Experience with enterprise technology risk assessments and control evaluations
  • Familiarity with regulatory frameworks like NIST, ISO, and HIPAA
  • Strong analytical and problem-solving skills related to technology and cybersecurity risks
  • Relevant certifications such as CISSP or CISM preferred

Responsibilities

  • Lead enterprise risk identification, assessment, and reporting activities
  • Develop and improve risk methodologies and governance processes
  • Facilitate cross-functional risk assessments and establish risk metrics
  • Partner with stakeholders to ensure effective risk ownership and decision-making
  • Conduct technology risk assessments and evaluate emerging technology risks
  • Oversee the Business Continuity Program and lead recovery planning activities
  • Coordinate audit readiness activities and support vendor risk assessments

Benefits

  • Comprehensive health coverage: Medical, Dental, and Vision
  • Discretionary bonus opportunity
  • 401(k) plan with financial benefits
  • 120 hours of annual vacation and 72 hours of paid sick time off
  • 11 paid holidays and 3 floating holidays
  • Employee Assistance Program and Voluntary Benefits
  • Employee recognition program
Full Job Description
Senior Technology & Business Risk Manager

LOCATION:

On-Site in Louisville, CO

THE ROLE:

The Senior Technology & Business Risk Manager is responsible for leading enterprise technology risk management, business continuity, governance, compliance coordination, and operational resilience activities across the organization. This role oversees risk assessment processes, business continuity planning, control governance, third-party risk management, audit readiness, and technology risk initiatives that support business operations, cybersecurity objectives, regulatory compliance, and organizational growth. The position partners closely with Infrastructure Engineering, Cybersecurity, Software Development, Business Intelligence, Compliance, Legal, Quality, and business stakeholders to ensure risks are identified, evaluated, communicated, and appropriately mitigated. This position is designed for a hands-on technology risk leader capable of assessing cybersecurity, infrastructure, operational, and business risks while helping mature enterprise governance, risk management, and operational resilience programs. The successful candidate must be comfortable operating in a highly technical environment and actively participating in risk assessments, audits, technology reviews, business continuity planning, vendor risk evaluations, control design discussions, and operational resilience initiatives.

WHAT YOU'LL DO:

Enterprise Risk Management & Governance
  • Lead enterprise-wide risk identification, assessment, prioritization, mitigation, and reporting activities across technology and business domains.
  • Maintain and continuously improve the enterprise risk register, risk methodologies, scoring models, and governance processes
  • Facilitate cross-functional risk assessments involving cybersecurity, infrastructure, applications, cloud technologies, data protection, operational processes, and third-party services
  • Establish risk metrics, key risk indicators (KRIs), dashboards, and executive reporting processes.
  • Coordinate risk review activities with business leaders and IT stakeholders to ensure risk ownership and mitigation accountability
  • Support risk-informed decision-making throughout technology and business initiatives
  • Partner with business leaders to identify, assess, and monitor operational, strategic, regulatory, and enterprise risks beyond traditional technology domains
  • Drive enterprise risk governance through regular risk reviews, executive reporting, and cross-functional governance committees

Technology Risk & Cybersecurity Governance
  • Partner with Infrastructure Engineering and Cybersecurity teams to evaluate technical risks, control effectiveness, and remediation strategies
  • Assess enterprise risks associated with emerging technologies, including Artificial Intelligence (AI), automation, cloud-native platforms, and evolving digital capabilities
  • Support governance activities aligned with NIST CSF, NIST RMF, ISO 27001, SOC 2, HIPAA, SOX and related frameworks
  • Assist with root cause analysis, risk investigations, control reviews, and corrective action planning
  • Conduct and lead technology risk assessments involving infrastructure, cloud services, enterprise applications, identity and access management, cybersecurity controls, endpoint technologies, and operational technology environments
  • Stay current with emerging cybersecurity threats, regulatory developments, risk management practices, and technology trends

Business Continuity & Operational Resilience
  • Lead development and continuous improvement of the Business Continuity Program
  • Conduct Business Impact Assessments (BIAs) and recovery planning activities across business functions
  • Coordinate tabletop exercises, continuity testing, and resilience validation activities
  • Partner with Infrastructure and Security teams to ensure Disaster Recovery capabilities support business recovery objectives
  • Evaluate operational resiliency risks involving critical business processes, vendors, and technology dependencies
  • Support incident response reviews and lessons-learned activities following significant operational disruptions
  • Coordinate responses to customer security questionnaires, technology due diligence activities, and third-party assurance requests

Compliance, Audit & Third-Party Risk
  • Coordinate readiness activities for internal and external audits including SOC 2, HIPAA, ISO 27001, SOX, and related assessments
  • Partner with business and IT teams to collect audit evidence, validate controls, and track remediation activities
  • Support vendor risk assessments, third-party reviews, and ongoing vendor monitoring activities
  • Assist with policy development, control governance, and risk-related training initiatives
  • Monitor evolving regulatory requirements impacting technology, cybersecurity, privacy, and operational risk programs
  • Maintain documentation supporting governance, compliance, continuity, and risk management activities
  • Partner with Finance, Internal Audit, and business stakeholders to support SOX IT General Controls (ITGCs), application controls, control testing, remediation activities, and audit readiness efforts
  • Evaluate technology, cybersecurity, and operational control effectiveness and recommend improvements to reduce organizational risk exposure

Operational Governance & Leadership
  • Drive maturity improvements across enterprise risk, business continuity, and governance programs
  • Develop and maintain risk management procedures, methodologies, standards, and documentation
  • Drive accountability through governance reviews, risk reporting, mitigation tracking, and issue escalation processes
  • Support audit readiness and control effectiveness activities within regulated environments
  • Provide enterprise leadership by influencing cross-functional teams, facilitating governance forums, and driving accountability for organizational risk management activities
  • Foster a collaborative, risk-aware, and business-focused culture across the organization
  • Oversee the enterprise technology policy governance process, including policy lifecycle management, periodic reviews, and alignment with regulatory and business requirements


WHAT YOU'LL BRING:

  • Bachelor's degree in Information Technology, Information Systems, Cybersecurity, Computer Science, Engineering, Risk Management, or related technical field
  • 8+ years of progressive experience in IT Risk Management, Cybersecurity Governance, Enterprise Risk Management, Information Security, Internal IT Audit, GRC, or related disciplines
  • 5+ years of leadership experience leading enterprise risk, cybersecurity governance, business continuity, compliance, or technology risk programs
  • Experience conducting enterprise technology risk assessments and control evaluations
  • Demonstrated experience assessing enterprise technology environments, including infrastructure, cloud platforms, cybersecurity technologies, identity and access management, endpoint technologies, and enterprise applications
  • Experience implementing or supporting frameworks such as NIST CSF, NIST RMF, ISO 27001, COBIT, SOX ITGC, HIPAA Security Rule, SOC 2, HITRUST, or similar frameworks
  • Demonstrated ability to lead enterprise risk management, business continuity, governance, or cybersecurity risk programs
  • Strong organizational skills and ability to balance strategic planning with hands-on execution
  • Experience influencing business and technology leaders regarding risk decisions
  • Strong analytical and problem-solving capabilities involving technology, cybersecurity, operational, and business risks
  • Demonstrated understanding of enterprise infrastructure, cloud platforms, identity and access management, endpoint technologies, data protection, and cybersecurity controls
  • Comfortable participating in technical reviews, architecture discussions, risk assessments, and remediation planning
  • Ability to evaluate technical control effectiveness and communicate risk implications to leadership
  • Strong written and verbal communication skills with executive-level presentation abilities
  • Ability to communicate technical risk concepts to both technical and non-technical audiences
  • Collaborative mindset with the ability to influence stakeholders across multiple business functions
  • Experience operating within regulated or compliance-focused environments
  • Familiarity with healthcare, laboratory, biotechnology, or highly regulated industry frameworks
  • Experience presenting risk assessments and recommendations to executive leadership
  • CISSP, CISM, CRISC, CGRC, CISA, CBCP, PMP, or equivalent certifications, preferred
  • Experience with ServiceNow GRC, Archer, AuditBoard, Drata, or similar platforms, preferred
  • Experience within healthcare, diagnostics, biotechnology, pharmaceutical, or regulated industries, preferred
  • Experience supporting AI governance, AI risk management, or emerging technology oversight, preferred


WHAT YOU'LL GET:

  • Annual Base Salary Range $145,000 - $160,000
  • Discretionary Bonus opportunity
  • Comprehensive health coverage: Medical, Dental, and Vision
  • Insurance: Short/Long Term Disability and Life Insurance
  • Financial benefits: 401(k), Flex Spending Account
  • 120 hours of annual vacation
  • 72 hours of paid sick time off
  • 11 paid holidays + 3 floating holidays
  • Employee Assistance Program
  • Voluntary Benefits
  • Employee recognition program


WHAT TO EXPECT IN THE INTERVIEW PROCESS:

We want you to have a clear view of the IT Operations & End User Services Manager role-and we want to get to know the real you. Our interview process is designed to be thorough, transparent, and give you direct insight into what it's like to work here:
  1. Virtual Recruiter Screen - A conversation to understand your background, what motivates you, and where you're looking to grow.
  2. Hiring Manager Interview - A deeper discussion about your experience, skills, and approach.
  3. Final On-Site Interview - Tour our corporate headquarters; interview with additional members of the team to discuss alignment and fit.


Individual base compensation is based on various factors unique to each candidate, including skill set, experience, qualifications, and other job-related aspects.

About Biodesix

Biodesix is a molecular diagnostics company that develops and commercializes blood-based diagnostic tests for oncology indications. The company's tests are designed to provide physicians with clinically actionable information to improve patient outcomes and reduce the overall cost of care. Biodesix's flagship product, the GeneStrat test, is a non-invasive liquid biopsy test that helps physicians identify the optimal treatment for patients with advanced non-small cell lung cancer. The company was founded in 2005 and is headquartered in Boulder, Colorado.
Learn more about Biodesix
Size
200 employees
Market Cap
$117.4 million
Industry
NASDAQ

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