Eurofins Lancaster Laboratories

Senior Scientist - Pharmaceutical Materials Scientist

Eurofins Lancaster Laboratories$90K — $120K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Master's Degree (MS) with 2+ years of experience or a PhD in pharmaceutical science, chemistry, or chemical engineering.
  • Proficient in solid-state characterization techniques like x-ray powder diffraction and differential scanning calorimetry.
  • Familiar with infrared spectroscopy methods, including FTIR and NIR.
  • Skilled in addressing Materials Science challenges involving large molecules and particle characterization.
  • Experienced in amorphous solid dispersion strategies and solid form screening innovations.
  • Strong grounding in physical, analytical, and organic chemistry principles.
  • Effective organizational skills and the ability to communicate clearly in both oral and written formats.

Responsibilities

  • Conduct advanced solid-state characterization of large bRo5 molecules relevant to pharmaceuticals.
  • Apply innovative crystallization techniques for recrystallizing bRo5 compounds.
  • Collaborate with cross-functional project teams to manage crystallization and solid form screenings efficiently.
  • Define screening and characterization strategies in partnership with Medicinal Chemistry and Biopharmaceutics teams.
  • Tackle scientific challenges utilizing contemporary Materials Science techniques.
  • Contribute to pioneering new scientific methods within the Materials Science department.
  • Maintain precise and timely documentation in the electronic laboratory notebook system.

Benefits

  • Comprehensive medical, dental, and vision coverage.
  • Life and disability insurance options.
  • 401(k) plan with company matching contributions.
  • Generous paid vacation and holiday leave.
Full Job Description
We are seeking a highly innovative Materials Scientist with deep expertise in non-traditional solid-form strategies for beyond Rule-of-5 (bRo5) molecules, including PROTACs, RIPTACs, and molecular glues. This role will support the design of advanced solid form screening approaches, amorphous solid dispersion (ASD) formulations, predictive mathematical models. The position is based in Groton, CT (USA).

Role Responsibilities:
  • Conduct advanced solid-state characterization of large bRo5 molecules of pharmaceutical relevance.
  • Apply novel crystallization techniques to recrystallize bRo5 molecules.
  • Support multidisciplinary project teams and collaborate with colleagues to define and implement crystallization, polymorph, salt, and co-crystal screening activities according to project timelines.
  • Collaborate with colleagues in Medicinal Chemistry, Formulation and Biopharmaceutics to define and implement screening and characterization strategies consistent with solid form selection for clinical studies.
  • Solve scientific problems using contemporary Materials Science experimental techniques.
  • Contribute to the development of new scientific approaches and knowledge within the Materials Science organization.
  • Ensure contemporaneous and accurate entries are made in the electronic laboratory notebook system according to accepted good practice.


Qualifications
  • Master's Degree (MS) with 2+ years of experience or a PhD in pharmaceutical science, chemistry, chemical engineering, or related field.
  • Experience in pharmaceutical solid state characterization techniques (such as x-ray powder diffraction, polarized light microscopy, differential scanning calorimetry, thermogravimetric analysis, spectroscopy, etc.). Strong data analysis and interpretation skills.
  • Experience and understanding of infrared spectroscopy (FTIR, NIR, FT-Raman) and/or SSNMR.
  • Experience with solving Materials Science problems related to large molecules, e.g., solid state chemistry and particle characterization using experimental approaches and team collaboration.
  • Experience with amorphous solid dispersion strategies and ability to develop innovative solid form screening strategies.
  • Understanding of physical, analytical, and organic chemistry.
  • Good organizational skills, the ability to work independently, and excellent oral and written communication skills are required.
  • Experience in mathematical modeling.


Additional Information
  • The position is full-time, M- F 8 am to 5 pm
  • May be requested to work on weekends, overtime, and holidays based on business needs.
  • Candidates currently living within a commutable distance of Groton, CT are encouraged to apply.
  • Excellent full-time benefits, including comprehensive medical coverage, dental, and vision options
  • Life and disability insurance
  • 401(k) with company match
  • Paid vacation and holidays
  • #LI-EB1

About Eurofins Lancaster Laboratories

Eurofins Lancaster Laboratories is a leading contract research organization (CRO) providing analytical, research and testing services to clients in the pharmaceutical, biopharmaceutical, biotechnology, crop protection, chemical, food, environmental and consumer products industries. The company was founded in 1961 and has grown to become one of the largest CROs in the world, with over 50 locations in 20 countries. Eurofins Lancaster Laboratories is part of the Eurofins Scientific Group, a global leader in bioanalytical testing and laboratory services. The company's services include method development and validation, stability testing, quality control testing, and regulatory compliance support.
Learn more about Eurofins Lancaster Laboratories
Size
12,000 employees
Industry

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