Senior Scientist

Merck Group$105K — $158K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • BS in Chemistry or related field plus 5-7+ years of hands-on experience with advanced LC-MS, or a master's degree with 3-5+ years, or a PhD with 0-1+ years of experience.
  • Advanced experience with enzymatic and chemical methods of sample preparation for large biomolecule LC-MS.
  • Ability to work effectively in both independent and team settings.

Responsibilities

  • Lead development of LC-MS assays for quantitating proteins in complex mixtures.
  • Perform advanced characterization of large biomolecules including monoclonal antibodies and antibody drug conjugates.
  • Provide high-level analytical support to product development scientists and project teams.
  • Collaborate with multidisciplinary teams within R&D and manufacturing groups.
  • Conduct various sample preparation techniques for enhanced mass spectrometry workflows.

Benefits

  • Health insurance
  • Paid time off (PTO)
  • Retirement contributions
  • Additional workplace perquisites
Full Job Description
Your Role:

The Senior Scientist will join the Analytical R&D Department at MilliporeSigma at our Life Sciences R&D facility in St. Louis. In this role, you will be part of an active, multidisciplinary group of scientists dedicated to providing high level analytical support to product development scientists in R&D, manufacturing groups, and special project teams. You will be expected to lead development of LC-MS assays for the quantitation of proteins in complex mixtures. Additionally, you will perform advanced characterization of large biomolecules including monoclonal antibodies, multi-specifics, and antibody drug conjugates.

Who you are:

Minimum Qualifications:
  • BS in Chemistry or related field plus 5-7+ years of experience with demonstrated hands-on proficiency with advanced instrumentation, with high resolution and/or triple quadrupole LC-MS platforms OR a master's degree with 3-5+ years of stated above experience, OR a PhD with 0-1+ years of stated above experience
  • Advanced experience with a variety of enzymatic and chemical methods of sample preparation for large biomolecule LC-MS, such as digestion, enrichment, depletion, and labelling or related
  • Experience working and communicating effectively both independently and in a team-oriented environment


Preferred Qualifications:
  • Experience in absolute quantitation of proteins and antibodies by Multiple Reaction Monitoring (MRM) and/or Parallel Reaction Monitoring (PRM) mass spectrometry
  • Experience in bottom up, middle up/down, and/or top-down protein LC-MS workflows
  • Experience with specific workflows such as non-reduced and reduced intact mass analysis, peptide mapping, disulfide mapping, Post-Translational Modifications (PTM) characterization, glycosylation profiling, and/or free thiol analysis
  • Experience with bioinformatics related to the quantitation and characterization of large biomolecules such as UNIFI, BioPharma Finder, Mascot, and Scaffold
  • Proficiency in a variety of instrument platforms such as Thermo, Sciex, Waters, and Agilent mass spectrometers
  • Hands-on experience with MALDI-MS

Role must be based in St. Louis, MO

Pay Range for this position: $105,500 - $158,300. The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.

About Merck Group

Merck Group Careers

There has never been a more opportune time to join Merck Group, a leading science and technology company in healthcare, life science, and performance materials. Merck Group offers a plethora of job opportunities that cater to a variety of skills and professional aspirations, making it an ideal environment for both seasoned experts and those at the start of their career journey.

Work You’ll Do

At Merck Group, every team member contributes to breakthrough innovations in healthcare, life sciences, and electronics. The company's commitment to diversity and innovation fuels its leadership in various sectors, driving growth and transformation globally. Merck Group’s career paths are diverse, offering positions that challenge individuals to use their skills in new ways every day, supported by robust training programs and development opportunities.

Explore Job Opportunities and Growth

Merck Group is not just about jobs; it's about building a career. With a vast array of positions, from research and development to marketing and sales, the company is keen on hiring and nurturing talent to lead industry transformation. Merck Group’s dedication to professional growth is evident in its comprehensive benefits package and performance management processes that aim to maximize individual potential.

Internship Programs

Starting with an internship at Merck Group can be a pivotal step in securing a prosperous career. Interns gain invaluable industry experience, working alongside seasoned professionals and engaging in projects that offer real-world applications of their studies. Internships often lead to full-time employment opportunities, providing a seamless transition from education to professional employment.

Inclusive Culture and Leadership

Merck Group is proud of its inclusive culture that embraces diversity and fosters an environment where all employees can thrive. The company’s leadership is committed to creating a workplace where diverse ideas lead to innovative outcomes. Merck Group also offers diversity training to ensure all team members are equipped to contribute to the company’s inclusive goals.

Networking and Professional Development

Employees at Merck Group are encouraged to engage in networking and professional development activities that enhance their career trajectories. The company hosts various networking events, workshops, and seminars that are designed to hone skills and foster connections within the industry. Leadership development programs are also a cornerstone, preparing employees for future roles of increased responsibility.

Stay Connected with Merck Group Careers

Interested candidates can explore open positions that match their skills and interests through the Merck Group careers page. The company values curious, creative, and solution-driven team players who are eager to make an impact.

Keep Up to Date

Stay informed with career tips, insider perspectives, and industry-leading insights from Merck Group professionals. These resources are invaluable for those looking to advance their careers and stay ahead in a competitive job market.

Job Alert Emails

Personalize your subscription to receive job alerts, latest news, and insider tips tailored to your preferences from Merck Group. Discover the exciting and rewarding career opportunities that await.

SEARCH MERCK GROUP JOBS

READ CAREERS BLOG

Merck Group is continuously looking for individuals who are ready to drive innovation and lead in the global marketplace. Whether through full-time positions, internships, or leadership roles, Merck Group offers a career path filled with opportunities for growth, learning, and leadership.
Learn more about Merck Group

Similar Jobs

More Jobs at Merck Group

More Pharmaceuticals & Biotech Jobs

Find similar Senior Scientist jobs: