Asimov

Senior Scientist, Lentiviral Vector Cell Line Development

Asimov • $120K — $145K *
Boston, MA 02115In-Person
Pharmaceuticals & Biotech
5 - 7 years of experience
Today
Be an Early Applicant
Job Overview by Ladders

Qualifications

  • M.S. or PhD in Biological Engineering, Virology, Cell Biology, Molecular Biology, or similar field.
  • 7+ years of hands-on biopharma experience, including 4+ years in lentiviral vector producer or packaging cell line development.
  • 2+ years managing direct reports and providing technical guidance.
  • Track record of balancing hands-on lab work with high-level strategy and planning.
  • Experience communicating technical information to external stakeholders and adapting their needs into project plans.
  • Proven ability to publish scientific work and present at conferences.
  • Desirable: Experience with downstream purification, viral genome engineering, and bioreactor process development.

Responsibilities

  • Set strategic scientific roadmap for Lentiviral Vector cell line development platform.
  • Develop stable producer cell lines through transfection, cloning, and characterization.
  • Act as the main technical contact for customer and commercial projects, collaborating with the commercial team.
  • Lead and mentor scientists, ensuring high standards for experimental design and data management.
  • Participate in cross-functional teams, influencing cell line development strategy.
  • Drive innovation with new workflows and applications for viral vector production.
  • Conduct experiments and analyze data while maintaining comprehensive records.

Benefits

  • Join a nimble, forward-thinking synthetic biology startup.
  • Opportunity to directly influence the future of biological engineering.
  • Engage in a blend of strategic leadership with hands-on experimentation.
  • Support for research projects to enhance product quality attributes.
Full Job Description
We are hiring a Senior Scientist to lead our Lentiviral Vector Cell Line Development team in Boston, MA. This role blends strategic leadership with hands-on experimentation, giving you direct influence over our Lentiviral Vector platform roadmap and scientific vision. You will drive the creation of stable producer cell lines for lentiviral vector therapeutics while innovating next-generation cell line development workflows. This is a unique opportunity to work at a nimble, forward-thinking synthetic biology startup and help build the future of biological engineering.

About the Role:
  • Set and steer the scientific roadmap for the Lentiviral Vector cell line development (CLD) platform.
  • Perform lentiviral vector stable producer cell line development processes including transfection, pool generation, single cell cloning, clone screening and characterization, and cell banking using state-of-the-art equipment.
  • Serve as the primary Lentiviral Vector CLD technical contact on customer and commercial projects. Partner with our commercial team to present platform capabilities to prospective partners and translate customer requirements into executable CLD project plans.
  • Provide technical leadership and mentorship to scientists on the team, including managing direct report(s) and setting a high bar for experimental design, data analysis and record-keeping.
  • Represent Lentiviral Vector CLD on cross-functional and leadership-facing project teams, making calls on cell line development strategy and clearly communicating progress, risk and plans.
  • Support innovation through development of novel workflows and applications
  • Support research projects to develop viral vector production methods to enhance product quality attributes such as empty/full ratio, potency and/or cell targeting.
  • Work effectively as part of a cross-functional team in support of a Lentiviral Vector CLD platform and in collaboration with Synthetic Biology and Process Development teams.
  • Design experiments, analyze data, troubleshoot, and maintain detailed records.
  • Represent Lentiviral Vector CLD on project teams, making decisions for cell line development activities and effectively communicating results, progress and plans.
  • Represent Asimov's science externally through publications and presentations at leading industry conferences.


About You:
  • M.S. or PhD in Biological Engineering, Virology, Cell Biology, Molecular Biology, or a related field.
  • 7+ years of hands-on experience in biopharma, including 4+ years focused on lentiviral vector producer or packaging cell line development in support of GLP or GMP production of cell or gene therapies.
  • 2+ years of experience managing direct report(s) and providing technical guidance.
  • Proven track record balancing hands-on bench leadership with big-picture platform strategy and roadmapping.
  • Experience communicating technical work to external stakeholders and translating their needs into technical plans.
  • Demonstrated ability to communicate scientific work externally, evidenced by publications, patents, and/or conference presentations.
  • Experience with downstream purification and PQ assessment of lentiviral vectors, T-cell transduction assay, viral genome engineering, and/or host cell genome engineering related to virus production or producer cell line technologies is highly desired.
  • Experience with process development at Ambr or benchtop bioreactor scale is a plus.
  • Comfortable working with large, multidimensional datasets and applying statistical or computational methods to extract actionable biological or process insights.
  • Strong written and verbal communication skills required.

About Asimov

Asimov's Science Fiction is a science fiction magazine that was founded in 1977 by Isaac Asimov. The magazine publishes short stories, novellas, and novelettes, as well as book reviews and essays on science fiction. Asimov's Science Fiction is published by Dell Magazines, which is a subsidiary of Penguin Random House. The magazine is headquartered in New York City.
Learn more about Asimov
Size
100 employees
Industry
Media
* Ladders Estimates

Similar Jobs

Ad banner background

Get Ready For Your
Next Interview

More Jobs at Asimov

More Pharmaceuticals & Biotech Jobs

Find similar Senior Scientist, Lentiviral Vector Cell Line Development jobs:

NationwideBoston, MA