Pfizer

Senior Scientist, Culture Process Development

Pfizer • $93K — $156K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • PhD in relevant field (0-3 years experience) or Master's with 7+ years or BS with 9+ years experience in Biotechnology-related fields.
  • Experience in scalable mammalian cell culture processes and continuous manufacturing.
  • Strong understanding of metabolic pathways and process kinetics in mammalian cells.
  • Proficient in aseptic techniques and experimental design with data analysis capabilities.
  • Self-motivated and organized team player with a knack for innovative problem-solving.
  • Strong communication skills and attention to detail.
  • Able to thrive in a fast-paced, dynamic work environment.

Responsibilities

  • Design and execute experiments in scale-down models to create scalable manufacturing processes.
  • Lead technical efforts in technology transfer to pilot and GMP manufacturing sites.
  • Document experimental data and author reports for regulatory submissions.
  • Contribute to lab discussions on experimental designs and data interpretation.
  • Foster a safe and efficient lab environment as a collaborative team member.
  • Perform essential tasks during weekends when necessary.

Benefits

  • Eligibility for employee referral programs.
  • Comprehensive health benefits including medical, dental, and vision coverage.
  • Retirement savings options with company matching contributions.
  • Paid vacation, holidays, and personal days, along with caregiver/parental leave.
  • Support for health and wellness initiatives.
Full Job Description
What You Will Achieve

A Senior Scientist (R4) position is available in the Upstream Process Development group within the Bioprocess R&D organization. The successful applicant will join a team of scientists and engineers focused on developing and optimizing manufacturing processes for recombinant proteins and other modalities for early- and late-phase human clinical trials. In this role, the candidate will be responsible for designing and executing laboratory experiments in bench-top bioreactors and associated scale-down equipment with the goal of developing robust, scalable, and high productivity processes. The work will also involve collaborating with pilot, clinical, and commercial production facilities to ensure accurate technology transfer, successful large-scale production and associated regulatory filing activities. The candidate may also be involved in cutting edge technology development projects that seek to improve production processes and control strategies leveraging various process analytical technologies.

How You Will Achieve It

  • Design and execute experiments in appropriate scale-down models in an effort to develop robust, high yield, and scalable manufacturing processes


  • Serve as upstream technical lead; ensure accurate technology transfer to pilot and GMP manufacturing facilities; provide technical support during manufacturing campaign as needed


  • Timely and accurately document data in electronic lab notebooks; author technical reports and contribute to relevant sections of regulatory submissions such as IND and BLA


  • Participate and contribute to discussions in lab and project team meetings on design of experiments and interpretation of data


  • Contribute to safe, efficient, and harmonious lab environment; strong lab citizen and collaborative team player


  • Occasionally work over the weekend to passage flasks, sample bioreactors or perform other essential tasks


QUALIFICATIONS

Must Have

  • PhD degree with 0-3 years of experience in biotechnology/biopharma industry or Master's Degree with 7+ years of post-graduate experience or BA/BS with 9+ years of experience with a degree in Chemical/Biochemical Engineering, Bioengineering, Biotechnology, Cell Biology, Microbiology or relevant field


  • Experience in development and characterization of cost effective, scalable mammalian cell culture processes for therapeutics production; process intensification and continuous manufacturing; Scale-up/scale-down of cell culture processes


  • Good understanding of reactions involved in metabolic pathways and process kinetics in mammalian cells


  • Competency in aseptic laboratory technique, ability to design complex experiments, analyze and interpret data


  • Self-motivated, organized, and capable of working independently and in a collaborative environment and should have demonstrated ability to drive projects by coming up with innovative solutions


  • Demonstrates strong attention to detail, and strong oral and written communication skills


  • Has ability to work in a fast-paced team environment with changing priorities


  • Demonstrated effectiveness in collaborative projects, and ability to communicate effectively with scientists and management in a highly matrixed organization


  • Demonstrated passion for innovation and a creative approach to developing new technologies


Nice To Have

  • Expertise in perfusion bioreactor operations, including process setup, control, troubleshooting of mammalian cell culture processes


  • Hands-on experience with high-throughput bioreactor platforms, including ambr15 and ambr250 systems


  • Expertise in process modeling, CFD, multivariate data analysis, and AI/ML-based predictive modeling to support process characterization and enhance process understanding


  • Proficiency in Python programming, workflow automation, and software/app development to create scalable tools for experimental design, data processing, advanced analytics, visualization, and knowledge-sharing across process development organizations


PHYSICAL/MENTAL REQUIREMENTS

  • Lifting, sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform complex data analysis


NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

  • May require occasional work on the weekend for cell culture process-related essential tasks


  • May need to travel occasionally to attend internal meetings or external conferences


Other Job Details

  • Work Location Assignment: On Premise


  • Eligible for Employee Referral


Relocation support may be available based on business need and eligibility

The annual base salary for this position ranges from $93,600.00 to $156,000.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 12.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Research and Development

About Pfizer

Hospira, Inc. is the provider of injectable drugs and infusion technologies. Through its broad, integrated portfolio, Hospira is uniquely positioned to Advance Wellness™ by improving patient and caregiver safety while reducing healthcare costs. The company is headquartered in Lake Forest, Ill., and has approximately 16,000 employees.

Pfizer Careers

Joining Pfizer’s global team offers more than just job opportunities; it’s a chance to be a part of a company that leads with science and innovates for better health. As a leading biopharmaceutical company, Pfizer is at the forefront of transforming lives through innovation, leadership, and diversity. Work You’ll Do At Pfizer, you will collaborate with some of the brightest minds in the industry, engaging in work that enhances global health and saves lives. Our culture thrives on intellectual curiosity, professional growth, and inclusivity, making every day a learning opportunity. Here, your skills will be honed, your professional acumen will be expanded, and you will be part of a team that values the power of diverse insights to drive success. Pfizer’s Leadership and Growth Lead and innovate with Pfizer, where we value the growth of each employee. Our leadership is committed to providing employees with the training and resources needed to excel in their careers. Pfizer offers a variety of career paths, including roles in research, marketing, finance, technology, and more, each offering a unique blend of challenges and rewards. Internship and Employment Opportunities Start your career with Pfizer through our internship programs or dive straight into a full-time position. We are hiring individuals who are passionate about healthcare and who seek to make a difference in the world. Our internships provide invaluable industry experience, networking opportunities, and a potential pathway to full-time employment. Benefits and Culture Pfizer is dedicated to fostering a workplace where all employees feel valued and can achieve their full potential. We offer competitive benefits packages that support the health, well-being, and financial security of our employees and their families. At Pfizer, you’ll find a culture that encourages collaboration, innovation, and continuous learning. Join Our Team Explore the numerous job opportunities at Pfizer by searching open positions that match your skills and interests. We look for driven, curious, and innovative team players who are ready to advance their careers in a transformative company. Stay Connected Keep up to date with career tips, insider perspectives, and industry-leading insights you can put to use today—all from the people who work here. Personalize your subscription to receive job alerts, latest news, and insider tips tailored to your preferences. Discover the exciting and rewarding career opportunities that await at Pfizer. Interview and Resume Tips Prepare for your future with Pfizer by utilizing our resources for resume building and interview preparation. We provide guidance on how to effectively showcase your skills and experiences to align with the needs of a position at Pfizer. Our goal is to help you succeed in securing a role that suits your professional goals and personal growth aspirations. Pfizer: A Place Where You Can Make a Difference Every position at Pfizer contributes to our mission of making the world a healthier place. Whether through direct patient care, research innovation, or corporate roles that support our operations, your work will have global impact. Join us in our journey to change lives—explore Pfizer careers today.
Learn more about Pfizer
Size
79,000 employees
Market Cap
$285.9 billion
Industry
Net Income
$9.6 billion
Founded
1849
5 Year Trend
+9%
Revenue
$41.9 billion
NASDAQ

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